What’s new with DNA and RNA?
Eukaryotic gene expression is regulated at multiple layers. This session will cover emerging new mechanisms of gene expression regulation, centered around DNA and RNA. We will hear updates on regulation at the nucleosome structure and chromatin conformation level, how noncoding RNAs could impact transcription, and RNA modifications in post-transcriptional gene expression regulation. This session also will introduce diverse modern imaging technologies to visualize transcription activity and spatial transcriptome.
Keywords: chromatin structure, noncoding RNA, RNA modifications, super-resolution imaging, spatial transcriptome
Who should attend: students, postdocs and anyone interested in gene expression regulation, nucleosome structure and chromatin conformation, noncoding RNA and RNA modifications, super-resolution imaging and spatial transcriptome
Theme song: "The DNA Song" by Jam Campus (parody of "Trap Queen" by Fetty Wap)
This session is powered by nucleic acids.
Talks
- Cracking the nucleus: Finding order in chaos — Clodagh O'Shea, Salk Institute
- EM structures of nucleosomes with chaperones — Karolin Luger, University of Colorado Boulder
- Structural mechanism of human telomerase holoenzyme — Kelly Nguyen, Medical Research Council Laboratory of Molecular Biology
- Studying DNA-related processes on DNA curtains — Ilya Finkelstein, University of Texas at Austin
- m6A in the action of regulating the regulators — Kathy (Fange) Liu, University of Pennsylvania
- Jeannie Lee, Massachusetts General Hospital
- RNA methylation multitasking on chromatin — Blerta Xhemalce, University of Texas at Austin
- RNA methylation in gene expression regulation — Chuan He, University of Pennsylvania
- Visualizing RNA in life cells — Timothy Stasevich, Colorado State University
- Visualizing the dynamic genome during development, Alistair Boettiger, Stanford University
- 3D in situ RNA sequencing — Xiao Wang, Broad Institute and Massachusetts Institute of Technology
- Engineering the repetitive 3D genome in human disease— Jennifer Phillips–Cremins, University of Pennsylvania
Learn more
Check out all ten thematic symposia planned for the 2022 ASBMB annual meeting:
- Diversity, equity and inclusion
- Protein machines and disorder
- Signaling
- Quality control in organelles
- Metabolism
- Enzymology
- RNA/DNA
- Membranes/lipids
- Glycobiology
- Education and professional development
Enjoy reading ASBMB Today?
Become a member to receive the print edition four times a year and the digital edition monthly.
Learn moreFeatured jobs
from the ASBMB career center
Get the latest from ASBMB Today
Enter your email address, and we’ll send you a weekly email with recent articles, interviews and more.
Latest in Science
Science highlights or most popular articles
Antibiotic sensor directly binds drug in resistant bacteria
Researchers at Drexel University uncover how the vancomycin-resistant bacterial sensor binds to the antibiotic, offering insights to guide inhibitor design that restores antibiotic effectiveness against hospital-acquired infections.
ApoA1 reduce atherosclerotic plaques via cell death pathway
Researchers show that ApoA1, a key HDL protein, helps reduce plaque and necrotic core formation in atherosclerosis by modulating Bim-driven macrophage death. The findings reveal new insights into how ApoA1 protects against heart disease.
Omega-3 lowers inflammation, blood pressure in obese adults
A randomized study shows omega-3 supplements reduce proinflammatory chemokines and lower blood pressure in obese adults, furthering the understanding of how to modulate cardiovascular disease risk.
AI unlocks the hidden grammar of gene regulation
Using fruit flies and artificial intelligence, Julia Zeitlinger’s lab is decoding genome patterns — revealing how transcription factors and nucleosomes control gene expression, pushing biology toward faster, more precise discoveries.
Zebrafish model links low omega-3s to eye abnormalities
Researchers at the University of Colorado Anschutz developed a zebrafish model to show that low maternal docosahexaenoic acid can disrupt embryo eye development and immune gene expression, offering a tool to study nutrition in neurodevelopment.
Top reviewers at ASBMB journals
Editors recognize the heavy-lifters and rising stars during Peer Review Week.