Proteins and proteomics

More than just omics

Meet the three co-organizers of an intimate meeting that focuses on transcription from all angles.

Decoding microglial language

Emory University scientists characterize extracellular vesicles that facilitate intercellular communication.

Small protein plays a big role in viral battles

Nef, an HIV accessory protein, manipulates protein expression in extracellular vesicles, leading to improved understanding of HIV-1 pathogenesis.

Study suggests that estrogen may drive nicotine addiction in women

Research findings open the door to targeted therapies for controlling nicotine use.

Bedrest may affect cholesterol dynamics differently depending on age

Unraveling physical inactivity’s effects on the body could lead to new ways to mitigate its negative effects.

Focusing on a pivotal axis in chemoresistance

Answers may lie in microRNA changes at the intersection of a cell cycle–regulating protein and a transcription factor that plays various roles in cancer.

How an enzyme protects the colon

Molecules that play crucial roles in lipid synthesis in other tissues also affect the progression of colitis.

There’s more than one way to be good

Researchers find a new role for HDL cholesterol in the immune system.

Guengerich proposes a paradigm shift in enzyme biochemistry

His lab probed the mechanism used by a P450 enzyme to catalyze a critical, three-step reaction in sterol biosynthesis: the metabolism of lanosterol.