Lipids and membranes
Missing lipid shrinks heart and lowers exercise capacity
Researchers uncovered the essential role of PLAAT1 in maintaining heart cardiolipin, mitochondrial function and energy metabolism, linking this enzyme to exercise capacity and potential cardiovascular disease pathways.
Building better tools to decipher the lipidome
Chemical engineer–turned–biophysicist Matthew Mitsche uses curiosity, coding and creativity to tackle lipid biology, uncovering PNPLA3’s role in fatty liver disease and advancing mass spectrometry tools for studying complex lipid systems.
Redefining lipid biology from droplets to ferroptosis
James Olzmann will receive the ASBMB Avanti Award in Lipids at the ASBMB Annual Meeting, March 7–10, just outside of Washington, D.C.
Fasting, fat and the molecular switches that keep us alive
Nutritional biochemist and JLR AE Sander Kersten has spent decades uncovering how the body adapts to fasting. His discoveries on lipid metabolism and gene regulation reveal how our ancient survival mechanisms may hold keys to modern metabolic health.
Exploring the link between lipids and longevity
Meng Wang will present her work on metabolism and aging at the ASBMB Annual Meeting, March 7-10, just outside of Washington, D.C.
Defining a ‘crucial gatekeeper’ of lipid metabolism
George Carman receives the Herbert Tabor Research Award at the ASBMB Annual Meeting, March 7–10, just outside of Washington, D.C.
Mapping fentanyl’s cellular footprint
Using a new imaging method, researchers at State University of New York at Buffalo traced fentanyl’s effects inside brain immune cells, revealing how the drug alters lipid droplets, pointing to new paths for addiction diagnostics.
Cholesterol as a novel biomarker for Fragile X syndrome
Researchers in Quebec identified lower levels of a brain cholesterol metabolite, 24-hydroxycholesterol, in patients with fragile X syndrome, a finding that could provide a simple blood-based biomarker for understanding and managing the condition.
How lipid metabolism shapes sperm development
Researchers at Hokkaido University identify the enzyme behind a key lipid in sperm development. The findings reveal how seminolipids shape sperm formation and may inform future diagnostics and treatments for male infertility.