Disease mechanisms and treatments
New gene new strides in gangliosidosis
A gene that decreases disease progression in mice provides a new direction for human therapy.
Newly discovered genetic variant clarifies why Parkinson’s develops
Researchers at the University of Florida have found that the mutation called RAB32 Ser71Arg both causes the condition and could show how to halt it.
Illuminating the dark serum immunoglobulome
Researchers in the Netherlands shine a light on unique antibody repertories of severe COVID-19 patients.
'Protein sandwich' could transform cancer drug discovery
A team led by Alessio Ciulli has defined a new class of so-called “intramolecular bivalent glue,” which binds proteins that would otherwise stay apart.
What’s next in the Ozempic era?
Diabetes, weight loss and now heart health: A new family of drugs is changing the way scientists are thinking about obesity — and more uses are on the horizon.
New surfactant could improve lung treatments for premature babies
Researchers report progress toward an alternative to animal-derived formulation.
New compound offers hope for deadly tropical disease
Schistosomiasis drug candidate overcomes limitations of current treatment.
Drugs of the future will be easier and faster to make, thanks to mRNA
But researchers still have to work out a few remaining kinks.
Sibling study reveals mechanism for genetic disease
Using proteomics experiments, researchers found that old proteins pile up in the mitochondria of people with a form of adult-onset muscular dystrophy.