Disease mechanisms and treatments

Cracking cancer’s code through functional connections
News

Cracking cancer’s code through functional connections

July 2, 2025

A machine learning–derived protein cofunction network is transforming how scientists understand and uncover relationships between proteins in cancer.

Neurobiology of stress and substance use
Profile

Neurobiology of stress and substance use

June 19, 2025

MOSAIC scholar and proud Latino, Bryan Cruz of Scripps Research Institute studies the neurochemical origins of PTSD-related alcohol use using a multidisciplinary approach.

Proteomic variation in heart tissues
Journal News

Proteomic variation in heart tissues

June 17, 2025

By tracking protein changes in stem cell–derived heart cells, researchers from Cedars-Sinai uncovered surprising diversity — including a potential new cell type — that could reshape how we study and treat heart disease.

Calcium channel linked to cancer drug resistance
Journal News

Calcium channel linked to cancer drug resistance

June 12, 2025

Researchers discover a protein associated with carboplatin-resistant retinoblastoma, suggesting this protein could be a promising therapeutic target. Read more about this recent Journal of Biological Chemistry paper.

Host fatty acids enhance dengue virus infectivity
Journal News

Host fatty acids enhance dengue virus infectivity

June 12, 2025

Researchers in Germany find that viral replication depends on host enzymes that synthesize lipids, revealing potential metabolic targets for antiviral intervention. Read more about this recent Journal of Biological Chemistry paper.

Butter, olive oil, coconut oil — what to choose?
Journal News

Butter, olive oil, coconut oil — what to choose?

May 28, 2025

Depending on the chain length and origin of the fat, regular fat consumption changes the specific makeup of fats in bloodstream and affect mild to severe cholesterol patterns. Read about this recent Journal of Lipid Research study.

Meet Lan Huang
Interview

Meet Lan Huang

May 19, 2025

Molecular & Cellular Proteomics associate editor uses crosslinking mass spec to study protein–protein interactions to find novel therapeutics.

Influenza gets help from gum disease bacteria
Journal News

Influenza gets help from gum disease bacteria

May 15, 2025

Scientists discover that a protease from Porphyromonas gingivalis enhances viral spread. Read more about this recent Journal of Biological Chemistry paper.

Innovative platform empowers scientists to transform venoms into therapeutics
Journal News

Innovative platform empowers scientists to transform venoms into therapeutics

May 13, 2025

Scientists combine phage display and a “metavenome” library to discover new drugs that bind clinically relevant human cell receptors. Read about this recent Molecular & Cellular Proteomics paper.