Cholesterol regulatory genes predict liver transplant outcomes
Lipid signatures for a rare neurological disorder

News and Ideas

Disease-linked mutations disrupt protein phase behavior
Researchers find that pathogenic missense mutations are enriched threefold in phrase-separating intrinsically disordered regions of proteins.

Getting students excited about introductory biology
Assistant professor rethinks how he teaches foundational biology by flipping his classroom and using real-world case studies to help students connect molecular mechanisms to lived experiences.

The dual role of asprosin in chronic fatty liver disease
Researchers uncover a hormone called asprosin that may serve as a potential biomarker for the diagnosis of chronic fatty liver disease and monitoring disease progression.

Novel inhibitor targets RAS-driven cancers
Researchers in Louisville identify a small-molecule drug that blocks RALGEF signaling downstream of mutant RAS. The compound suppresses tumor growth with low toxicity, revealing a new therapeutic strategy for RAS-driven malignancies.

Garcia–Blanco, Li elected to VASEM
They are two of 22 Virginia-based scientists honored for their leadership in science, engineering and medicine.
Reflecting on science, learning and leadership
ASBMB President Joan Conaway reflects on her term, celebrating the society’s resilience, advocacy, journal growth and commitment to education, while looking ahead to a vibrant future under incoming president Ed Eisenstein.

Backward design and beyond: Lessons from a molecular genetics classroom
Associate professor reflects on an early teaching misstep and explains how backward design, clear learning objectives and reflective tools reshaped assessment, clarified expectations and helped students take ownership of their learning.

Catching tau in the act
Using a new proximity-labeling approach, researchers reveal how tangles of the brain-associated protein tau may disrupt RNA biology long before neurons die.

Designing scientific careers, not just experiments
Universities are rethinking how they prepare scientists for careers beyond the bench. From myIDP to Vanderbilt’s Career Architect, programs help trainees clarify values, explore options and build intentional paths forward.
Meet Our Contributors
Jessica Desamero
Courtney Chandler
Jay Thakkar
Poornima Sankar
Beyond the bench: On a mission to build an inclusive scientific community
Benjamin Garcia will receive the ASBMB Ruth Kirschstein Diversity in Science Award at the ASBMB Annual meeting, April 12–15 in Chicago. Read More
Who decides when a grad student graduates?
Courtney Chandler
Careers Columnist
Ph.D. programs often don’t have a set timeline. Students continue with their research until their thesis is done, which is where variability comes into play. Read More
Computational biosciences illuminate how molecular condensates form
Rohit Pappu will receive the 2025 DeLano Award for Computational Biosciences at the ASBMB Annual Meeting, April 12-15 in Chicago. Read More
Quantifying how proteins in microbe and host interact
“To develop better vaccines, we need new methods and a better understanding of the antibody responses that develop in immune individuals,” author Johan Malmström said. Read More
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