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From the journals: JBC
Articles in the Journal of Biological Chemistry investigate immune receptor binding; barrel-shaped organelles called vaults; de novo dNTP synthesis; and a specific SNARE inhibitor.
From the journals: MCP
Articles in the journal Molecular & Cellular Proteomics report peptide signatures for ID'g bacteria. the first evidence of phosphorylation in Francisella tularensis, how pathogenic phleboviruses bud and exit host cells, and more.
Crystal building blocks of triglycerides
Using methods that include crystallography and cryo-electron microscopy, recent work in three labs has defined structures and mechanisms in triglycerides, Michael Airola writes.
Rounding out the year with nickel and zinc
Quira Zeidan ends her yearlong series marking the 150th anniversary of Dmitri Mendeleev’s periodic table with a look at the two metallic elements with chemical symbols Ni and Zn.
JBC: Tor comes to the fore in autophagy
Yoshinori Ohsumi, Takeshi Noda and colleagues at the National Institute for Basic Biology in Japan discovered that the Tor protein controls the breakdown process of autophagy in yeast cells. Martin Spiering writes about their classic paper.
JBC: Paving the way for disease-resistant rice
Scientists have found that a rice immune receptor triggers reactions in response to fungal proteins, a first step toward using gene editing to prevent the crop destruction caused by rice blast disease.
JLR junior associate editors organize virtual issues
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JLR: Secrets of fat and the lymph node
Some 20 years ago, Sander Kersten isolated a protein that acts as a control for how our bodies store or burn fat. Recently, he wrote in the Journal of Lipid Research about why loss of this protein can be fatal to mice.
MCP: When prions are personal
In a quest to cure the deadly protein folding disease that runs in his wife’s family, a researcher publishes a new assay for monitoring protein levels in the journal Molecular & Cellular Proteomics.
From the journals: December 2019
Chasing the structure of a histone’s N-terminus tail. Highlighting the role of lipids in mediating endoplasmic reticulum structure. Defining the components of a bacteria’s biofilm matrix. Researchers tackle these tasks and more in our latest roundup…
Ants in the lab
Take a peek inside the labs of Danny Reinberg and Shelley Berger, who use ants to study the role of epigenetics and gene expression in behavior and aging.
Oxygen sensing and adapting to altitude
Gregg Semenza is one of three physician–scientists sharing the 2019 Nobel Prize in physiology and medicine for their discoveries related to the protein complex hypoxia-inducible factor and the red blood cell–producing hormone it controls.
Annual meeting to highlight JLR junior associate editors
These four outstanding early-career scientists will present their work on April 7 in San Diego.
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