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What are the advantages of an mRNA vaccine for COVID-19?
They’re easier to manufacture than traditional vaccines, but scientifically their history is checkered
NIH project homes in on COVID racial disparities
Amid a wavering federal response that has allowed staggering levels of disease to sweep the country, the All of Us program is a potential bright spot.
The time of trials: Waiting for a coronavirus vaccine
An infected and impatient world needs protection from Covid-19, but rushing it won't be easy. How can we speed up a complicated process?
How 'good' does a COVID-19 vaccine need to be?
New study finds that a coronavirus vaccine’s effectiveness may have to be higher than 70% or even 80% before Americans can safely stop relying on social distancing.
Estrogen receptor antagonist and gallstone disease
A new compound blocks the G protein–coupled estrogen receptor, preventing the formation of cholesterol gallstones in female mice.
The sugar in semen makes HIV drugs less effective
High levels of fructose can obstruct antivirals from linking with viruses, researchers at the University of Iowa find.
Psoriasis Awareness Month 2020
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Bent into shape: The rules of tree form
How do trees find their sense of direction as they grow? Researchers are getting to the root — and the branches — of how the grandest of plants develop.
From the journals: MCP
Researchers identify acetylation sites in a coronavirus, find that deamidation is rife in the immunopeptidome and explore the role of CEP5 in plants’ tolerance of drought. Read about these new papers in the journal Molecular & Cellular Proteomics.
From the journals: JBC
A metal ion that transforms tau. A new target to take out cancer cells. One substitution that abolishes enzyme allostery. Read about recent papers on these topics and more in the Journal of Biological Chemistry.
COVID-19 retractions show that the science is working as it should
Severe scrutiny of two major papers, including one about the effectiveness of hydroxychloroquine, is part of science's normal process of self-correction, explains Mark R. O’Brian.
In the future, lab mice will live in computer chips, not cages
As COVID-19 shuttered laboratories across the U.S., many researchers were forced to euthanize the animals they study. Lindsay Gray, a rodent surgeon in an animal research lab that faced this dilemma, argues here there is a safer, more effective way.
Proteomics reveals hallmarks of aging in brain stem cells
Early in adulthood, the brain regenerates lost myelin effectively, but remyelination falters with age. Researchers seek to understand why — and what the change may mean for people with multiple sclerosis.
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