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Untangling the genetics that underlie our facial features
After turning up hundreds of genes with hard-to-predict effects, some scientists are now probing the grander developmental processes that shape face geometry.

From the journals: JLR
A safer combination therapy for liver disease. A mechanistic pathway of the pathophysiology of NASH. A novel therapeutic target for heart failure. Read about recent papers on these topics.

Insulin injections could one day be replaced with rock music
Using mice, researchers engineered cells to release insulin in response to specific sound waves: the music of the band Queen.

From the journals: JBC
Protein cleavage in polycystic kidney disease. Expanding tools to study ion channels. Mechanisms of 5-fluorouracil cytotoxicity and chemoresistance. Read about papers on these topics.

Detecting biomarkers for deadly lung disease
A group led by scientists from Genentech Inc is studying whether bioactive lipid species can predict idiopathic pulmonary fibrosis progression.

ASBMB journal events at #DiscoverBMB
The Journal of Biological Chemistry, the Journal of Lipid Research and Molecular & Cellular Proteomics are a big part of the society, so naturally they will be center stage in San Antonio.
FDA approves CRISPR–Cas9 therapy for sickle cell disease

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Vampire viruses prey on other viruses to replicate themselves
And they may hold the key to new antiviral therapies.

From the journals: MCP
A new enzyme is unlocked in bacterial photosynthesis. A molecular target for alcohol consumption is uncovered. A special issue offers new perspectives in ECM research. Read about these recent papers.

Understanding the cause of childhood Alzheimer's
Today is World Sanfilippo Awareness Day.

Today is International 15q Day
Take some time to read up on the three conditions that constitute this class of neurodevelopmental disorders.

Receptor regulation clues may scratch an itch
Thomas Sakmar’s lab found that a GPCR associated with a liver disease symptom is regulated in previously unknown ways, possibly leading to new therapies.

The promise of AI in precision medicine and immunotherapy for diabetes
Today is World Diabetes Day. To mark this observance, this article covers the many ways in which diabetes research and drug development stands to benefit from the use of AI.
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