Researchers at Vanderbilt University discover a correlation between cell levels of PMP22 and its misfolding in this inherited neuromuscular disorder.
These ligands are secreted to the cell membrane bound to their dedicated transporter. The authors describe the structure of this complex with the essential lipid.
When doctors offer multiple-gene panel tests to patients at risk for diseases such as cancer, a variant that hasn’t yet been deciphered might raise concerns with no answers.
Join the ASBMB Today mailing list
Sign up to get updates on articles, interviews and events.