Neurobiology
CRISPR epigenome editor offers potential gene therapies
Scientists from the University of California, Berkeley, created a system to modify the methylation patterns in neurons. They presented their findings at ASBMB 2025.
A new kind of stem cell is revolutionizing regenerative medicine
Induced pluripotent stem cells are paving the way for personalized treatments to diabetes, vision loss and more. However, scientists still face hurdles such as strict regulations, scalability, cell longevity and immune rejection.
Richard Silverman to speak at ASBMB 2025
Richard Silverman and Melissa Moore are the featured speakers at the ASBMB annual meeting to be held April 12-15 in Chicago.
From the Journals: JLR
Promising therapeutic candidate for steatosis. Unique lipid profiles in glycogen storage disease. Microglial lactic acid mediates neuroinflammation. Read about these recent papers.
Unsheathing the role of myelin lipids in Alzheimer’s disease
Xianlin Han, an ASBMB Breakthroughs speaker, discussed his pioneering work on lipidomics and the role of sulfatide lipids in Alzheimer's disease.
Lipid biomarkers hold clues to stroke recovery
Scientists at the University of Arizona found that a lipid mediator accumulates with the waves of inflammation associated with stroke and foamy macrophages.
From the JBC archives: Madness, indoles and mercury-based cathartics
A 1907 paper sought to resolve an ongoing question of whether indole, a bacterial molecule in the gut, could cause insanity if overproduced.
Mutant RNA exosome protein linked to neurodevelopmental defects
Researchers at Emory University find that a missense mutation impairs RNA exosome assembly and translation and causes neurological disease.
Adults grow new brain cells
How does the rare birth of these new neurons contribute to cognitive function?