Genes and genetics
Cholesterol regulatory genes predict liver transplant outcomes
Researchers identify a link between cholesterol-regulating genes and liver transplant success, which could improve donor screening and patient outcomes.
Disease-linked mutations disrupt protein phase behavior
Researchers find that pathogenic missense mutations are enriched threefold in phrase-separating intrinsically disordered regions of proteins.
Novel inhibitor targets RAS-driven cancers
Researchers in Louisville identify a small-molecule drug that blocks RALGEF signaling downstream of mutant RAS. The compound suppresses tumor growth with low toxicity, revealing a new therapeutic strategy for RAS-driven malignancies.
Sizing up cells: How stem cells know when to divide
Stanford University researchers find that stem cells control their size early in cell division across living multicellular systems.
From humble beginnings to unlocking lysosomal secrets
Monther Abu–Remaileh will receive the ASBMB’s 2026 Walter A. Shaw Young Investigator Award in Lipid Research at the ASBMB Annual Meeting, March 7-10 in Washington, D.C.
Fasting, fat and the molecular switches that keep us alive
Nutritional biochemist and JLR AE Sander Kersten has spent decades uncovering how the body adapts to fasting. His discoveries on lipid metabolism and gene regulation reveal how our ancient survival mechanisms may hold keys to modern metabolic health.
Exploring the link between lipids and longevity
Meng Wang will present her work on metabolism and aging at the ASBMB Annual Meeting, March 7-10, just outside of Washington, D.C.
The science of staying strong
Muscles power every movement, but they also tell the story of aging itself. Scientists are uncovering how strength fades, why some species resist it and what lifestyle and molecular clues could help preserve muscle health for life.
Discoveries made possible by DNA
The discovery of DNA’s double helix revealed how genetic information is stored, copied and expressed. Revisit that breakthrough and traces how it laid the foundation for modern molecular biology, genomics and biotechnology.