Annual Meeting

Connecting metabolism to development, disease and therapy

A 2022 annual meeting session on metabolism
Marian Walhout Scott Dixon
By Marian Walhout and Scott Dixon
Sept. 29, 2021

If you are wondering whether metabolism is important, consider the effect of holding your breath while you read through this introduction. Your genome will not change, and your RNA and protein expression patterns will not change much, if at all, but the abundance of numerous metabolites in your body will change substantially within seconds and ultimately produce a physiological response that restores homeostasis. 

Metabolism is complex and dynamic, involving hundreds of enzymes and reactions. Versions of many enzymes are found in most living organisms on earth. In development, metabolic processes are central for growth; in diseased tissues, metabolism is altered and contributes to pathology. Symbiotic or competitive metabolic interactions between organisms govern a broad swath of important biology in the immune system and gut. How these interactions are regulated by and coordinated with DNA-based, RNA-based and protein-based mechanisms remains under investigation. 

The metabolism field continues a rapid expansion. This session will explore a breadth of models and approaches being used to investigate how metabolism impacts development, homeostasis, disease and medicine.

Keywords: metabolism, metabolites, development, cancer, pathogen, drug action, lipids, cell fate 

Who should attend: anyone interested in learning how metabolism impacts development, disease or therapy

Theme song: “Stayin’ Alive” by the Bee Gees, because it’s all thanks to metabolism 

This session is powered by ATP. What else?

 

Talks

  • Interplay between metabolism and gene expression — Marian Walhout, University of Massachusetts Medical School
  • Identifying toxic metabolites and their roles in disease — Dohoon Kim, University of Massachusetts Medical School
  • Transcriptional regulation of primary and specialized metabolism — Siobhan Brady, University of California, Davis
  • Interorgan cross talk and metabolism regulation in Drosophila — Norbert Perrimon, Harvard University
  • Metabolic adaptation to oxidative stress at the host–microbe interface — Stavroula Hatzios, Yale University
  • Deconvoluting host-gut microbiota cometabolism — Pamela Chang, Cornell University
  • The tiny pharmacists within: How the human gut microbiome impacts drug metabolism and disposition — Peter Turnbaugh, University of California, San Francisco
  • Metabolic outliers in human disease — Ralph DeBerardinis, University of Texas Southwestern Medical Center
  • Lipid metabolism and ferroptosis — Scott Dixon, Stanford University
  • Too much and never enough: Synthetic excess and metabolic inefficiency of aneuploidy in tumorigenesis — Emma Watson, Harvard Medical School
  • Uncovering conditional vulnerabilities in cancerJason Cantor, University of Wisconsin
  • The genetics of tumor suppression by p53 — Maureen Murphy, Wistar Institute

Learn more

Check out all ten thematic symposia planned for the 2022 ASBMB annual meeting:

Enjoy reading ASBMB Today?

Become a member to receive the print edition monthly and the digital edition weekly.

Learn more
Marian Walhout
Marian Walhout

Marian Walhout is a professor and co-director of the Program in Systems Biology at the University of Massachusetts Medical School.
 

Scott Dixon
Scott Dixon

Scott Dixon is an associate professor in the biology department at Stanford University.

Featured jobs

from the ASBMB career center

Get the latest from ASBMB Today

Enter your email address, and we’ll send you a weekly email with recent articles, interviews and more.

Latest in Careers

Careers highlights or most popular articles

From the known to the unknown
How-to

From the known to the unknown

Feb. 20, 2024

The ASBMB’s technical editor offers tips and tricks for writing a manuscript introduction.

Calendar of events, awards and opportunities
Announcement

Calendar of events, awards and opportunities

Feb. 18, 2024

This week: ASBMB webinar on scientists running for office. Just added: An ASBMB career panel and networking event at The College of New Jersey!

Choosing an internship or a fellowship
Jobs

Choosing an internship or a fellowship

Feb. 16, 2024

There are other ways to begin your industry career other than being directly hired to a position. Here we explore the similarities and differences between internships and fellowships in industry.

Introducing short courses at Discover BMB in San Antonio
Annual Meeting

Introducing short courses at Discover BMB in San Antonio

Feb. 14, 2024

Learn how to launch your lab, your grant or your science communication skills in these intensive three-hour courses.

Calendar of events, awards and opportunities
Announcement

Calendar of events, awards and opportunities

Feb. 11, 2024

This week: ASBMB webinar on DEAI funding and training opportunities and the deadline for the NIEHS Scholars Connect Program. Just added: Lasker Foundation essay contest, GEN webinar on rare disease therapeutics, and SACNAS webinar on ChatGPT.

Defining success for yourself
Jobs

Defining success for yourself

Feb. 9, 2024

Our academic careers columnist offers some advice and questions to ask yourself to determine what your values are and how they should be reflected in your work life.