Second annual JBC Methods Madness tournament begins next week
Calling all scientists! The Journal of Biological Chemistry’s second annual Methods Madness tournament is here.
Last year’s tournament came down to the wire with #TeamCryo scraping by #TeamMassSpec to be crowned the first ever #JBCMethodsMadness champion. Can #TeamCryo repeat this year? Will #TeamMassSpec get revenge? Will both be upset by a new contender? Now is your chance to decide who makes it through.
The madness begins on Monday. (See tournament schedule below). Submit your bracket by Sunday for a chance to win a $100 gift card.
Round 1: The Scientific 16
Vote for your favorite methods by participating in polls posted by @jbiolchem.
Monday, March 15
9 a.m. – #TeamMassSpec vs. #TeamFRET
2 p.m. – #TeamImmuno vs. #TeamXRC
Tuesday, March 16
9 a.m. – #TeamCryo vs. #TeamMachine
2 p.m. – #TeamiPSC vs. #TeamLiveCell
Wednesday, March 17
9 a.m. – #TeamPCR vs. #TeamChroma
2 p.m. – #TeamCloning vs. #TeamNMR
Thursday, March 18
9 a.m. – #TeamCRISPR vs. #TeamSuperRes
2 p.m. – #TeamOmics vs. #TeamOpto
All times Eastern.
A note about JBC methods
It's well known that science progresses by building on the shoulders of those who came before. That's especially true for papers that report new tools — genetic constructs, small molecules, model organisms, etc. — that can be directly used by colleagues to jump-start a new project or resolve a technical hurdle. And at JBC, our high standards for rigor and reproducibility mean that readers can trust published tools to work as promised.
— Lila Gierasch, JBC editor-in-chief
Enjoy reading ASBMB Today?
Become a member to receive the print edition four times a year and the digital edition monthly.
Learn moreGet the latest from ASBMB Today
Enter your email address, and we’ll send you a weekly email with recent articles, interviews and more.
Latest in Science
Science highlights or most popular articles
Mapping the placenta’s hormone network
Study uncovers how the placenta actively metabolizes not only glucocorticoids but also novel androgens and progesterones, reshaping our understanding of pregnancy and its complications.
Biochemists and molecular biologists sweep major 2025 honors
Recent Nobel, MacArthur and Kimberly Prize honorees highlight the power of biochemistry and molecular biology to drive discovery, including immune tolerance, vaccine design and metabolic disease, and to advance medicine and improve human health.
Spider-like proteins spin defenses to control immunity
Researchers from Utrecht University discovered two distinct binding modes of a spider-shaped immune inhibitor found in serum.
A biological camera: How AI is transforming retinal imaging
AI is helping clinicians see a more detailed view into the eye, allowing them to detect diabetic retinopathy earlier and expand access through tele-ophthalmology. These advances could help millions see a clearer future.
AI in the lab: The power of smarter questions
An assistant professor discusses AI's evolution from a buzzword to a trusted research partner. It helps streamline reviews, troubleshoot code, save time and spark ideas, but its success relies on combining AI with expertise and critical thinking.
Training AI to uncover novel antimicrobials
Antibiotic resistance kills millions, but César de la Fuente’s lab is fighting back. By pairing AI with human insight, researchers are uncovering hidden antimicrobial peptides across the tree of life with a 93% success rate against deadly pathogens.