Which eight escaped the Scientific 16?
The Journal of Biological Chemistry’s Methods Madness tournament started off with a bang as last year’s finalist, #TeamMassSpec, faced off against the tournament newcomer #TeamFRET. #TeamFRET fought valiantly, but their supporters’ energy just didn’t transfer into votes. Meanwhile, #TeamMassSpec supporters turned up in SPECTRAcular numbers, pushing their team to the next round.
X-ray crystallographers around the world are rejoicing after #TeamXRC’s victory over #TeamImmuno. Votes proved to be too nonspecific for #TeamImmuno, whose supporters were unable to band together to provide support for their team. #TeamXRC advances to the next round while #TeamImmuno fades into the background.
#TeamCryo iced their competition, leaving #TeamMachine frozen in their tracks. Despite strategic support from #TeamMassSpec, it seems too many #TeamMachine supporters had their heads in the cloud, because they couldn’t find the algorithm needed to execute a win against the defending champion. #TeamCryo will move on to the Energetic Eight, where they will have a tough matchup against #TeamCRISPR.
In this cellular showdown, #TeamiPSC lacked the factors necessary to differentiate from the other losers of the week. In contrast, #TeamLiveCell was unphased by the pressure, shining bright in the win they captured. #TeamLiveCell has #TeamOmics in their frame as they focus on the next round.
#TeamPCR copied last year’s success to defeat #TeamChroma and advance to the next round. Supporters of #TeamChroma couldn’t match the flow rate of #TeamPCR voters, leaving #TeamChroma stuck in a stationary phase while their opponent mobilized. #TeamPCR will look to amplify their success with a win over #TeamMassSpec in the next round.
Resonating with their supporters, #TeamNMR put forth a dynamic performance to secure their second #JBCMethodsMadness win in as many years. Living up to their name, #TeamCloning replicated last year’s performance where they also lost against #TeamNMR in the first round. Perhaps they’ll find the winning recombination next year!
#TeamCRISPR excised #TeamSuperRes in the first round of the tournament and will move on to the next round. Despite their resolution to make it further this year, the win that #TeamSuperRes pictured was never fully deconvolved. #TeamCRISPR has their work cut out for them, facing off against the defending champion #TeamCryo.
Seq-ing a win in their tournament debut, #TeamOmics analyzed their competition and came out victorious. Seemingly unable to shed light on a winning formula, #TeamOpto failed to excite their supporters, resulting in their second tournament loss in as many years. Next, #TeamOmics will match up against #TeamLiveCell in the Energetic Eight round.
Round 2: The Energetic Eight
Monday, March 22
12 p.m. Eastern – #TeamNMR vs. #TeamXRC
Tuesday, March 23
12 p.m. Eastern – #TeamPCR vs. #TeamMassSpec
Wednesday, March 24
12 p.m. – #TeamLiveCell vs. #TeamOmics
Thursday, March 25
12 p.m. – #TeamCryo vs. #TeamCRISPR
Enjoy reading ASBMB Today?
Become a member to receive the print edition four times a year and the digital edition weekly.
Learn moreGet the latest from ASBMB Today
Enter your email address, and we’ll send you a weekly email with recent articles, interviews and more.
Latest in Science
Science highlights or most popular articles
Institute launches a new AI initiative to power biological research
Stowers investigator Julia Zeitlinger selected to head effort and leverage cutting-edge computational techniques to accelerate scientific discoveries.
From the journals: JLR
Fixation method to quantify brain metabolites. Belly fat and liver disease crosstalk. Stopping heart diseases in schizophrenic patients. Read about the recent JLR papers on these topics.
Does a protein hold the key to Alzheimer’s?
Researchers in Maryland and Massachusetts team up to study how SORL1 promotes tau trafficking and seeding in cells that leads to the neurodegenerative disorder.
Cracking the recipe for perfect plant-based eggs
It involves finding just the right proteins. With new ingredients and processes, the next generation of substitutes will be not just more egg-like, but potentially more nutritious.
MSU researchers leverage cryo-EM for decades-in-the-making breakthrough
Lee Kroos and Ben Orlando have reported the first high-resolution experimentally determined structures of the intramembrane protease SpolVFB.
From the Journals: MCP
Rapid and precise SARS-CoV-2 detection using mass spec. Mapping brain changes from drug addiction. Decoding plant osmotic stress response. Read about recent MCP papers on these topics.