Microbial engines of global change
Right now, redox cycling of the elements is happening on a genuinely global scale. These cycles are driven by the intricate electron-transfer chemistry of microbial organisms. Whether engaging in the molecular construction projects of the carbon, nitrogen or sulfur cycles or simply moving electrons to make a bioenergetic living, these smallest of creatures harness metals as cofactors to cycle and recycle the environment around us continuously.
Our symposia at the American Society for Biochemistry and Molecular Biology annual meeting — now called Discover BMB — in Seattle in March will cover several topics relating to the biochemistry and microbiology of elemental cycling, where complex metalloenzymes often are used to achieve startling transformations. Recently elucidated mechanisms, insight into how metallocofactors are harnessed to power the redox reactions of life around us, and surprising insights into the connections between metals, microbes and electrons all will be discussed.
With concerns for sustainability and a new energy economy, the microscopic world of biological chemistry has much to teach us.
Keywords: Metalloenzymes, enzyme mechanisms, microbiology, biochemistry, biogeochemistry.
Who should attend: All who are fascinated by how microorganisms shape the world around us and how the environment, in turn, shapes microbial biochemistry.
Theme song: “Electric Boogie (The Electric Slide)” by Marcia Griffiths.
This session is powered by electrons, and so are you.
Speakers
The enzymology of the carbon cycle
Jennifer Dubois (chair), Montana State University
Stephen Ragsdale, University of Michigan
Sean Elliott, Boston University
Cecilia Gomez Martinez, University of California, Berkeley
Kylie Allen, Virginia Tech
Frontiers of the nitrogen cycle
Eric Hegg (chair), Michigan State University
Yilin Hu, University of California, Irvine
Lisa Stein, University of Alberta
Akif Tezcan, University of California, San Diego
Metals, microbes and minerals
Sean Elliott (chair), Boston University
Eric Boyd, Montana State University
Jennifer Dubois, Montana State University
Jeff Gralnick, University of Minnesota
Christine Morrison, Colorado School of Mines
The complete list
Learn about all 11 symposia planned for Discover BMB 2023:- Protein Machines and Disorder
- Regulation of RNA
- Organelles, Mechanisms and Phase Properties of Cellular Quality Control
- Lipid Dynamics and Signals in Membrane and Protein Structure
- Frontiers in Carbohydrate Synthesis and Recognition
- Bias In, Bias Out in Data Science
- Cell Signaling — New Tools and Emerging Concepts
- Education and Professional Development
- Biochemistry of Elemental Cycling
- Advances in Organismal and Cellular Metabolism
- Artificial Intelligence and Machine Learning in Structural Biology, Drug Design and Systems Biology
Enjoy reading ASBMB Today?
Become a member to receive the print edition four times a year and the digital edition monthly.
Learn moreGet the latest from ASBMB Today
Enter your email address, and we’ll send you a weekly email with recent articles, interviews and more.
Latest in Science
Science highlights or most popular articles

Heat shock proteins as a promising breast cancer therapeutic
Researchers unveiled isoform-specific targets on heat shock protein 90 which may be beneficial in therapeutic development.

Optimized proteomic analysis of preserved biological tissue samples
Researchers have developed an optimized workflow for analyzing formalin-fixed paraffin-embedded tissue. This workflow provides an enhanced collection of unique proteins and phosphorylation sites for more detailed analysis of biological samples.

Blood proteomics reveals fungal infection signatures for faster diagnosis
Whole-blood proteomics identifies more than 3,000 host and 160 fungal proteins during cryptococcal infection, offering potential biomarkers for faster diagnosis and improved monitoring without invasive spinal taps.

When things get SAPpy: Novel insights into complement
Researchers have defined interactions between an innate immune protein and two of its known binding partners. They identified potential areas of crosstalk between the two binding interactions.

Glutathione pathway implicated in rare disease
Researchers found that glutathione metabolism plays a central role in the pathogenesis of rare disease methylmalonic aciduria using a novel multiomics approach.

A p-value for proteins
Kyoto University researchers developed UniScore, a new tool that uses a target-decoy method to filter false positives in proteomic searches, helping scientists set thresholds and improve reliability when analyzing complex protein data.