Health Observance

Alcohol Awareness Month

ASBMB Today Staff
By ASBMB Today Staff
April 18, 2018

April is Alcohol Awareness Month, sponsored by the National Council on Alcoholism and Drug Addiction. This year's theme is "Changing attitudes: It's not a 'rite of passage.'"

Essay: A journey to sobriety
Just days before graduating with his Ph.D., pseudonymous health systems researcher Dr. 24hours was arrested for drunk driving. Read his moving essay on his journey to recovery and what it cost him.

Infographic: The biochemistry of alcohol abuse
In an exclusive-to-ASBMB-Today rendering, an undergraduate studying biochemistry demonstrated how alcohol dehydrogenase converts a molecule nicknamed "el feliz" (the happy) into "el doloroso" (the painful). Find out how here.

Journal of Biological Chemistry

News: A link between noncoding RNAs and alcoholic liver disease
What can a study of microRNAs upregulated in a mouse model of alcoholism tell us about the inflammation that leads to alcoholic liver disease? Read about the paper

Research findings: A receptor driving fatty liver disease
Alcoholic liver disease, or steatohepatosis, is a common complication of alcoholism. Scientists late last year reported the identification of a nuclear receptor that drives fat accumulation in the liver in response to ethanol. Read more

Research findings: How alcohol slows healing
Did you know that alcohol can delay the healing of bone fractures? Researchers investigated the molecular mechanism for this effect, which can increase mortality from traumatic injuries. They found that alcohol reduces TGF-beta 1 production in response to the bone remodeling factor osteopontin, which may explain problems with fracture healing. Read more

Molecular & Cellular Proteomics

Research findings: Diagnosing oral cancers
Alcohol use is a major risk factor for cancers of the oral cavity (including tongue, lip, floor of mouth, and hard palate). Scientists in Taiwan used a targeted proteomics assay to discover diagnostic biomarkers for oral cancer. Read more

Journal of Lipid Research

News: Alcohol and hepatitis interact to raise cholesterol
Excessive alcohol use and the viral infection hepatitis B are both known to damage the liver. Researchers recently discovered that alcohol and hepatitis have synergistic effects on the liver, dramatically affecting cholesterol metabolism. Read a brief summary of their research here.

Research findings: Obesity compounds alcohol's effect
Damage to the liver from alcohol can coexist with obesity-related liver diseases. Scientists assayed all lipids in the liver of lean and obese mice after alcohol consumption and found that obesity dramatically increased the inflammation and oxidative stress that alcohol caused. Read more

Classic study: How drinking affects "bad" cholesterol
In this classic article, researchers showed that acetaldehyde, which is produced from ethanol by alcohol dehydrogenase, can react with lipoproteins in the liver. The reaction may explain the dramatically higher very low density lipoprotein cholesterol levels observed in heavy alcohol users. Read more

Research findings: how drinking affects "good" cholesterol
Even though alcohol consumption raises liver fat and cholesterol levels, it is known to slightly reduce the risk of heart disease. In this study, researchers tested the hypothesis that alcohol may change the amount of reverse cholesterol transport, or removal of free cholesterol from the peripheral tissues to return it to the liver. Read more

ASBMB Today Staff
ASBMB Today Staff

This article was written by a member or members of the ASBMB Today staff.

Join the ASBMB Today mailing list

Sign up to get updates on articles, interviews and events.

Latest in Science

Science highlights or most popular articles

Why you need more vitamin D in the winter
Wellness

Why you need more vitamin D
in the winter

January 26, 2020

With less exposure to sunlight in winter, adults should take in at least 600 international units per day of vitamin D from supplements or foods like oily fish, mushrooms and fortified dairy.

From the journals: MCP
Journal News

From the journals: MCP

January 25, 2020

Read about capturing a peptide link between migraines and opioid-induced sensitivity, profiling autologous body fluid exosomes and finding the RSK in melanoma protein interactions.

From the journals: JBC
Journal News

From the journals: JBC

January 24, 2020

Recent topics include misfolded tau proteins in Alzheimer’s disease, how enzymes trim peptides and how a parasite hijacks the immunity of its host.

Early immune response may improve cancer immunotherapies
Journal News

Early immune response may improve cancer immunotherapies

January 23, 2020

University of Illinois at Chicago researchers and colleagues report a new mechanism for detecting foreign material during early immune responses.

Do sperm offer the uterus a secret handshake?
Journal News

Do sperm offer the uterus
a secret handshake?

January 22, 2020

Why does it take 200 million sperm to fertilize a single egg? A female immune response is one reason. A molecular handshake may help sperm survive the bombardment.

A new hotspot for cyclooxygenase inhibition
Lipid News

A new hotspot
for cyclooxygenase inhibition

January 21, 2020

Drugs like aspirin dampen inflammation by inhibiting certain enzymes but can have nasty gastrointestinal side effects, so enzymologists are investigating the structure of the enzymes’ active sites in hopes of designing more selective inhibitors.