Cholesterol as a novel biomarker for Fragile X syndrome
Journal News

Cholesterol as a novel biomarker for Fragile X syndrome

By Pearce Hyatt
Researchers in Quebec identified lower levels of a brain cholesterol metabolite, 24-hydroxycholesterol, in patients with fragile X syndrome, a finding that could provide a simple blood-based biomarker for understanding and managing the condition.
Journal News

How lipid metabolism shapes sperm development

Researchers at Hokkaido University identify the enzyme behind a key lipid in sperm development. The findings reveal how seminolipids shape sperm formation and may inform future diagnostics and treatments for male infertility.
How lipid metabolism shapes sperm development

News and Ideas

Upcoming opportunities
Announcement

Upcoming opportunities

Nov. 26, 2025

#ASBMB26 late-breaking abstract submission opens on December 8. Register by Jan. 15 to get the early rate on our Annual Meeting.

Mass spec method captures proteins in native membranes
Journal News

Mass spec method captures proteins in native membranes

Nov. 25, 2025

Yale scientists developed a mass spec protocol that keeps proteins in their native environment, detects intact protein complexes and tracks drug binding, offering a clearer view of membrane biology.

Laser-assisted cryoEM method preserves protein structure
Journal News

Laser-assisted cryoEM method preserves protein structure

Nov. 25, 2025

University of Wisconsin–Madison researchers devised a method that prevents protein compaction during cryoEM prep, restoring natural structure for mass spec studies. The approach could expand high-resolution imaging to more complex protein systems.

Method sharpens proteome-wide view of structural changes
Journal News

Method sharpens proteome-wide view of structural changes

Nov. 25, 2025

Researchers developed a method that improves limited proteolysis coupled with mass spectrometry, separating true changes from abundance or splicing effects.

Discoveries made possible by DNA
Feature

Discoveries made possible by DNA

Nov. 24, 2025

The discovery of DNA’s double helix revealed how genetic information is stored, copied and expressed. Revisit that breakthrough and traces how it laid the foundation for modern molecular biology, genomics and biotechnology.

Bibel named assistant professor
Member News

Bibel named assistant professor

Nov. 24, 2025

She began her position at Loyola Marymount University in August 2025.

ASBMB launches Insights in Biochemistry and Molecular Biology
Announcement

ASBMB launches Insights in Biochemistry and Molecular Biology

Nov. 20, 2025

The new journal will be helmed by Benjamin Garcia as inaugural editor-in-chief and will start accepting submissions in early 2026.

Unraveling the language of histones
Profile

Unraveling the language of histones

Nov. 20, 2025

Philip Cole presented his research on how posttranslational modifications to histones are involved in gene expression and how these modifications could be therapeutically targeted to treat diseases like cancer.

How Alixorexton could transform narcolepsy treatment
News

How Alixorexton could transform narcolepsy treatment

Nov. 18, 2025

A new investigational drug, alixorexton, targets the brain’s orexin system to restore wakefulness in people with narcolepsy type 1. Alkermes chemist Brian Raymer shares how molecular modeling turned a lab idea into a promising phase 3 therapy.

Meet Our Contributors

Jessica Desamero
Jessica Desamero
Jay Thakkar
Jay Thakkar
Poornima Sankar
Poornima Sankar
Courtney Chandler
Courtney Chandler
Beyond the bench: On a mission to build an inclusive scientific community

Benjamin Garcia will receive the ASBMB Ruth Kirschstein Diversity in Science Award at the ASBMB Annual meeting, April 12–15 in Chicago. Read More

Computational biosciences illuminate how molecular condensates form

Rohit Pappu will receive the 2025 DeLano Award for Computational Biosciences at the ASBMB Annual Meeting, April 12-15 in Chicago. Read More

Quantifying how proteins in microbe and host interact

“To develop better vaccines, we need new methods and a better understanding of the antibody responses that develop in immune individuals,” author Johan Malmström said. Read More

Who decides when a grad student graduates?
Courtney Chandler

Careers Columnist

Ph.D. programs often don’t have a set timeline. Students continue with their research until their thesis is done, which is where variability comes into play. Read More

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