Science Communication

My cat’s coat is mostly white with dark tabby patches. What’s going on?

Dori Grijseels
By Dori Grijseels
Oct. 24, 2021

Have you ever wondered why your cat’s coat looks the way it does? Wonder no longer! Earlier this month, Emily Summerbell, a PhD student at Emory University, tweeted a ‘tweetorial’ on cat coat genetics. I used it to figure out the underlying genetics for my own cat’s coat.

This is my cat ‘Little Excuse’ (because when he’s sleeping on your lap, you’ve got an excuse to not get up). 

Excuse has a short coat, which is controlled by the FGF5 gene. Short hair (L) is the dominant trait, meaning that if one out of two copies, or alleles, of the gene encodes for short hair, the cat will end up with short hair. Excuse is either homozygous, meaning he has two short hair alleles (LL), or heterozygous, meaning he has one short hair, and one long hair allele (Ll).

Cat2-445x791.jpg
Adriaan Grijseels
Cat tax.

Though Excuse is for the majority white (we’ll get back to that later), he generally has dark-colored fur. This is encoded by the TYRP1 gene, for which the black allele is dominant. If he would have the allele for orange hair, this would override the black color, so the lack of any orange means that he has the recessive allele for the orange gene.

Back to the white fur. White fur is caused by the KIT gene, but it is not all-or-nothing. As you can see, Excuse is more than 50% white, which indicates that he is probably homozygous for the dominant white gene (SS).

Lastly, although it’s not clearly visible in this picture, Excuse’s dark patches have a tabby pattern to them. This is caused by the agouti and tabby genes, where the agouti gene determines whether a cat has a solid color coat, and the tabby gene determines the exact pattern.

Emily goes into much more detail in her Twitter thread, explaining colorpoint coat patterns, cats with diluted colors and more. If you are wondering why your cat looks the way it does, this thread will tell you all you need to know.

But in the meantime, what colour is your cat’s coat — and do you know why?

 
Cat3-890x445.jpg
Humberto Arellano on Unsplash
What type of coat does your cat have?

Enjoy reading ASBMB Today?

Become a member to receive the print edition four times a year and the digital edition monthly.

Learn more
Dori Grijseels
Dori Grijseels

Dori Grijseels is a neuroscience PhD student at the University of Sussex.

Get the latest from ASBMB Today

Enter your email address, and we’ll send you a weekly email with recent articles, interviews and more.

Latest in Science

Science highlights or most popular articles

From humble beginnings to unlocking lysosomal secrets
Award

From humble beginnings to unlocking lysosomal secrets

Feb. 20, 2026

Monther Abu–Remaileh will receive the ASBMB’s 2026 Walter A. Shaw Young Investigator Award in Lipid Research at the ASBMB Annual Meeting, March 7-10 in Washington, D.C.

Chemistry meets biology to thwart parasites
Award

Chemistry meets biology to thwart parasites

Feb. 19, 2026

Margaret Phillips will receive the Alice and C. C. Wang Award in Molecular Parasitology at the ASBMB Annual Meeting, March 7-10 in Washington, D.C.

ASBMB announces 2026 JBC/Tabor awardees
Award

ASBMB announces 2026 JBC/Tabor awardees

Feb. 18, 2026

The seven awardees are first authors of outstanding papers published in 2025 in the Journal of Biological Chemistry.

Missing lipid shrinks heart and lowers exercise capacity
Journal News

Missing lipid shrinks heart and lowers exercise capacity

Feb. 18, 2026

Researchers uncovered the essential role of PLAAT1 in maintaining heart cardiolipin, mitochondrial function and energy metabolism, linking this enzyme to exercise capacity and potential cardiovascular disease pathways.

Decoding how bacteria flip host’s molecular switches
Award

Decoding how bacteria flip host’s molecular switches

Feb. 17, 2026

Kim Orth will receive the Earl and Thressa Stadtman Distinguished Scientists Award at the ASBMB Annual Meeting, March 7–10, just outside of Washington, D.C.

Defining JNKs: Targets for drug discovery
Award

Defining JNKs: Targets for drug discovery

Feb. 12, 2026

Roger Davis will receive the Bert and Natalie Vallee Award in Biomedical Science at the ASBMB Annual Meeting, March 7–10, just outside of Washington, D.C.