Health Observance

Alcohol Awareness Month

ASBMB Today Staff
By ASBMB Today Staff
April 18, 2018

April is Alcohol Awareness Month, sponsored by the National Council on Alcoholism and Drug Addiction. This year's theme is "Changing attitudes: It's not a 'rite of passage.'"

Essay: A journey to sobriety
Just days before graduating with his Ph.D., pseudonymous health systems researcher Dr. 24hours was arrested for drunk driving. Read his moving essay on his journey to recovery and what it cost him.

Infographic: The biochemistry of alcohol abuse
In an exclusive-to-ASBMB-Today rendering, an undergraduate studying biochemistry demonstrated how alcohol dehydrogenase converts a molecule nicknamed "el feliz" (the happy) into "el doloroso" (the painful). Find out how here.

Journal of Biological Chemistry

News: A link between noncoding RNAs and alcoholic liver disease
What can a study of microRNAs upregulated in a mouse model of alcoholism tell us about the inflammation that leads to alcoholic liver disease? Read about the paper

Research findings: A receptor driving fatty liver disease
Alcoholic liver disease, or steatohepatosis, is a common complication of alcoholism. Scientists late last year reported the identification of a nuclear receptor that drives fat accumulation in the liver in response to ethanol. Read more

Research findings: How alcohol slows healing
Did you know that alcohol can delay the healing of bone fractures? Researchers investigated the molecular mechanism for this effect, which can increase mortality from traumatic injuries. They found that alcohol reduces TGF-beta 1 production in response to the bone remodeling factor osteopontin, which may explain problems with fracture healing. Read more

Molecular & Cellular Proteomics

Research findings: Diagnosing oral cancers
Alcohol use is a major risk factor for cancers of the oral cavity (including tongue, lip, floor of mouth, and hard palate). Scientists in Taiwan used a targeted proteomics assay to discover diagnostic biomarkers for oral cancer. Read more

Journal of Lipid Research

News: Alcohol and hepatitis interact to raise cholesterol
Excessive alcohol use and the viral infection hepatitis B are both known to damage the liver. Researchers recently discovered that alcohol and hepatitis have synergistic effects on the liver, dramatically affecting cholesterol metabolism. Read a brief summary of their research here.

Research findings: Obesity compounds alcohol's effect
Damage to the liver from alcohol can coexist with obesity-related liver diseases. Scientists assayed all lipids in the liver of lean and obese mice after alcohol consumption and found that obesity dramatically increased the inflammation and oxidative stress that alcohol caused. Read more

Classic study: How drinking affects "bad" cholesterol
In this classic article, researchers showed that acetaldehyde, which is produced from ethanol by alcohol dehydrogenase, can react with lipoproteins in the liver. The reaction may explain the dramatically higher very low density lipoprotein cholesterol levels observed in heavy alcohol users. Read more

Research findings: how drinking affects "good" cholesterol
Even though alcohol consumption raises liver fat and cholesterol levels, it is known to slightly reduce the risk of heart disease. In this study, researchers tested the hypothesis that alcohol may change the amount of reverse cholesterol transport, or removal of free cholesterol from the peripheral tissues to return it to the liver. Read more

ASBMB Today Staff
ASBMB Today Staff

This article was written by a member or members of the ASBMB Today staff.

Join the ASBMB Today mailing list

Sign up to get updates on articles, interviews and events.

Latest in Science

Science highlights or most popular articles

A proposal to use CRISPR to prevent opioid overdoses is a useless approach to healthcare
News

A proposal to use CRISPR to prevent opioid overdoses is a useless approach to healthcare

September 27, 2020

Nicholas McCarty of New York University writes that genetically engineering drug users’ brains is short-sighted, reactive and unnecessary.

Lessons from how the polio vaccine
News

Lessons from how the polio vaccine

September 26, 2020

Despite the polio vaccine’s long-term success, manufacturers, government leaders and the nonprofit that funded the vaccine’s development made several missteps.

From the journals: MCP
Journal News

From the journals: MCP

September 25, 2020

How marine iguanas mark their turf. A new way to study Parkinson’s disease. Glycosylation in influenza A. Read about recent papers on these topics in the journal Molecular & Cellular Proteomics.

Gut microbiome shaped by dietary sphingolipids
Journal News

Gut microbiome shaped by dietary sphingolipids

September 22, 2020

A new tracing method described in the Journal of Lipid Research offers clues on how a macronutrient interacts with the microbes that live inside us.

From the journals: JBC
Journal News

From the journals: JBC

September 21, 2020

Proteases that fire up the flu. A sulfate pocket to take out MRSA. Proteins that prompt cancer protrusions. Read about recent papers on these topics and more.

AeroNabs promise powerful, inhalable protection against COVID-19
News

AeroNabs promise powerful, inhalable protection against COVID-19

September 20, 2020

As the world awaits vaccines to bring the COVID-19 pandemic under control, UC San Francisco scientists have devised a novel approach to halting the spread of SARS-CoV-2, the virus that causes the disease.