In Memoriam

In memoriam: Ulrich auf dem Keller

Swarnali  Roy
May 13, 2024

Ulrich auf dem Keller, a leader in wound healing research and mass spectrometry-based proteomics technology, died September 1, 2023 at the age of 49.

Ulrich auf dem Keller

Born on April 5, 1974 and raised in Mülheim an der Ruhr, Germany, auf dem Keller received his undergraduate diploma in biochemistry in 2000. He then joined ETH, Zurich in the biology department under the mentorship of Pfizer Academic Award winner Sabine Werner where he identified Nrf2 as a key player in the cellular stress response and studied Nrf-mediated gene expression in keratinocytes in the prevention of skin tumors. He obtained his Ph.D. in 2005. 

auf dem Keller moved to the Centre for Blood Research, Vancouver, Canada, in 2006 to join Christopher Overall’s lab where he quantified changes in the proteome and analyzed the nature of protein amino termini analysis (N-terminome) using iTRAQ-TAILS technology and showed that loss of a single protease could perturb the proteolytic signaling network and enhance inflammation. 

In 2009, auf dem Keller started an independent lab in ETH, Zurich as a senior scientist and group leader.  He exploited the capability of iTRAQ-TAILS to exploring the substrate degradome of matrix metalloproteinase and translated his research to address complex proteolytic activities in healing impairments. In 2017, he moved to the section of protein science and biotherapeutics at Technical University of Denmark Bioengineering in Lyngby as a professor. He continued there until his death, exploring the quantitative proteomics approach in complex biological matrices.

auf dem Keller had more than 150 publications with 6,587 citations to date. He received a Herbert Tabor Young Investigator Award in 2011 from the American Society for Biochemistry and Molecular Biology for his studies of proteolytic events in the skin. 

Colleagues remember auf dem Keller as a stellar scientist and a fantastic mentor and friend. He was instrumental in the overall growth of his department and his students. He spoke Latin and ancient Greek, had an interest in classical music and was an outstanding viola player. 

He is survived by his wife and two children.

Enjoy reading ASBMB Today?

Become a member to receive the print edition monthly and the digital edition weekly.

Learn more
Swarnali  Roy

Swarnali Roy is a postdoctoral researcher in the Laboratory of Bioorganic Chemistry at the National Institute of Diabetes and Digestive and Kidney Diseases.

Related articles

In memoriam: Daniel Atkinson
ASBMB Today Staff
In memoriam: Charles Rock
Naushin Raheema

Get the latest from ASBMB Today

Enter your email address, and we’ll send you a weekly email with recent articles, interviews and more.

Latest in People

People highlights or most popular articles

This MOSAIC scholar’s journey brought her home to share science
Profile

This MOSAIC scholar’s journey brought her home to share science

May 23, 2024

Melissa Ramirez uses computations and experiments to design new reactions and mentorship to grow the research community.

More than just omics
Interview

More than just omics

May 21, 2024

Meet the three co-organizers of an intimate meeting that focuses on transcription from all angles.

2024 Goldwater scholars announced
Award

2024 Goldwater scholars announced

May 20, 2024

Thirteen of the scholarship recipients are ASBMB student members.

In memoriam: Edith C. Wolff
In Memoriam

In memoriam: Edith C. Wolff

May 20, 2024

She was an enzyme biochemist at the National Institutes of Health and a former assistant to the editor of the Journal of Biological Chemistry.

This MOSAIC scholar believes in the power of perseverance
Diversity

This MOSAIC scholar believes in the power of perseverance

May 16, 2024

Wagner Silva Dantas aims to develop new approaches to reducing fat mass while preserving muscle mass by studying a crucial regulator for maintaining redox balance.

ASBMB honors 2024 outstanding student chapter
Student Chapters

ASBMB honors 2024 outstanding student chapter

May 15, 2024

Founded just three years ago, the University of South Alabama chapter shows leadership in educational activities, commitment to increasing public scientific awareness and more.