Journal News

JBC editors weigh in on AI in science publishing

In an editorial, they say they’ll allow its use in manuscript preparation but not during the review process
Marissa Locke Rottinghaus
July 24, 2023

Earlier this week, the Journal of Biological Chemistry published an editorial to define appropriate and inappropriate uses of artificial intelligence technology in the “preparation and review of manuscripts being considered for publication.”

The editorial states that AI technology:

  • Can be used to prepare manuscript text to improve clarity

  • Cannot be listed as an author on a manuscript

  • Cannot be used in any part of the review process


Roger Colbran, a professor of molecular physiology and biophysics at Vanderbilt University School of Medicine and an associate editor of the JBC, authored the editorial with Editor-in-Chief Alex Toker of Beth Israel Deaconess Medical Center and Harvard Medical School.

“The rapid development and continued evolution of AI-based tools makes it hard to get a handle on their limitations in real-life use,” Colbran said. “These uncertainties make it important for the publishing industry, including the JBC, to define clear policies surrounding the acceptable and unacceptable uses of current AI-based technologies, with a clear understanding that they will need to be regularly updated as the technologies are further developed.”

The editorial acknowledges the potential benefits that AI technology may provide to non-native English speakers preparing manuscripts for submission, stating that the JBC will “welcome authors to make use of generative AI technologies in editing the text of their manuscript, in much the same way that authors may make use of more traditional editing services.” If AI is used for the editing of a manuscript, it must be included in the acknowledgements section of the manuscript, the editorial says.

“AI-driven tools have the potential to significantly reduce the amount of time and effort that scientists must dedicate to writing essentially any documents, be they research articles, reviews, book chapters, grants, or manuscript/grant critiques,” Colbran said. “There are also benefits in allowing scientists to rapidly learn about new areas of science. This could drive an increase in the overall efficiency of the entire research enterprise by allowing researchers to dedicate more time to doing actual science.”

Finally, the editorial states that AI may not be used for manuscript review, such as during the writing of manuscript critiques or decision letters. It points to the possibility that using AI may violate data privacy rights and cites published concerns about the confidentiality. Uploading a manuscript to a public AI tool may allow “retained conversations to be accessed by their AI trainers to improve future performance,” it says.

“There are significant concerns about the confidentiality of any information that is provided to these systems,” Colbran said. “Additional generative AI tools are being rapidly developed to ‘create’ raw image data, potentially including gels, blots and micrographs. Such synthesized data may be very hard to detect using the image analysis pipelines currently used by journals and publishers.”

Enjoy reading ASBMB Today?

Become a member to receive the print edition monthly and the digital edition weekly.

Learn more
Marissa Locke Rottinghaus

Marissa Locke Rottinghaus is the science writer for the ASBMB.

Get the latest from ASBMB Today

Enter your email address, and we’ll send you a weekly email with recent articles, interviews and more.

Latest in Opinions

Opinions highlights or most popular articles

An open letter to the ASBMB executive director search committee
Open Letters

An open letter to the ASBMB executive director search committee

Sept. 19, 2023

"As you sift through the applications ... look for signs of altruism, vision and an investment mentality rather than the extent of administrative experience and managerial acumen," Pete Kennelly writes.

Scientific publishing, then and now

Scientific publishing, then and now

Sept. 8, 2023

Fifty years ago, “editors provided constructive feedback that improved our manuscripts,” Sudhansu K. Dey writes. That happens less nowadays.

On our wall: A bird’s eye view of metabolism

On our wall: A bird’s eye view of metabolism

Sept. 7, 2023

To understand the complex relationships of the metabolic cycles and pathways, it helps to have the big picture, so a professor and students in Pakistan created one.

Wellness and trauma
Editor's Note

Wellness and trauma

Aug. 31, 2023

Telling stories helps us heal. Here’s my trauma story. Now I want to read yours.

An ancient practice in need of modern-day support
Health Observance

An ancient practice in need of modern-day support

Aug. 29, 2023

August is National Breastfeeding Month.

Exploring careers in microscopy

Exploring careers in microscopy

Aug. 22, 2023

During a mini-internships, Laura McCormick learned about working at a core facility and for a manufacturer.