Annual Meeting

Understanding the inner workings of biological machines

Molecular motors: 2020 annual meeting track
Nathan Alder Jochen Zimmer
By Nathan Alder and Jochen Zimmer
Sept. 1, 2019

Many biological macromolecules assemble into complexes to perform their physiological functions. These molecular machines range in complexity from relatively simple molecules to large macromolecular assemblies, and they are designed to perform specific tasks within the cell. This thematic session will cover exciting new advances in our understanding of the structure, function and engineering of molecular machines. The session will encompass the wide range of molecular assemblies that accomplish diverse and often essential tasks within a cell, including molecular motors responsible for protein processing and vesicle trafficking as well as supramolecular complexes mediating energy transduction, transport and protein synthesis.

Presentations in this track will cover a wide range of experimental and technical approaches, such as advances in structural biology (cryo-electron microscopy, X-ray crystallography and nuclear magnetic resonance spectroscopy), single molecule biophysics and super-resolution imaging. It also will cover novel conceptual advances, including new insights into the design of natural and synthetic molecular machines and how energy is transduced to power biological nanomachines at the molecular level.

Keywords: molecular motors, protein complexes, transporters, force generation and transduction, supramolecular assemblies.

Who should attend: those fascinated by structure–function relationships in biological systems, how macromolecules undergo modular assembly and what kinds of energetic input power the work of molecular machines.

Theme song: “Ghosts in My Machine” by Annie Lennox.

This track is powered by ATP and ion gradients.

Talks

  • Single molecule biophysics — Carlos Bustamante, University of California, Berkeley
  • Myosin: Structure, function, regulation and disease — Michelle Peckham, University of Leeds
  • Watching a fine-tuned molecular machine at work: Structural and functional studies of the 26S proteasome — Andreas Martin, University of California, Berkeley
  • Integrated 3D tomography and computational modeling to study forces in metaphase spindles — Stefanie Redemann, University of Virginia School of Medicine
  • Functional assembly of the mitochondrial protein transport machinery — Nathan Alder, University of Connecticut
  • Nascent protein selection and triage at the ribosome exit site — Shu-ou Shan, California Institute of Technology
  • Structure of the alternative complex III from Flavobacterium johnsoniae in a supercomplex with cytochrome c oxidase — Robert Gennis, University of Illinois
  • Special capabilities of the ribosomal machinery — Roland Beckman, Ludwig-Maximilians-Universität München
  • Sugary coats: Synthesis and secretion of extracellular polysaccharides — Jochen Zimmer, University of Virginia
  • Molecular assemblies of membrane remodeling and scission — James Hurley, University of California, Berkeley
  • Hi-fi molecular transmission via crisscross cooperativity — William Shih, Harvard University
  • Activation of the exocyst tethering complex for SNARE complex regulation and membrane fusion — Mary Munson, University of Massachusetts Medical School

Enjoy reading ASBMB Today?

Become a member to receive the print edition monthly and the digital edition weekly.

Learn more
Nathan Alder
Nathan Alder

Nathan Alder is an associate professor in the department of molecular and cell biology at the University of Connecticut.

Jochen Zimmer
Jochen Zimmer

Jochen Zimmer is a professor in the department of molecular physiology and biological physics at the University of Virginia.

Featured jobs

from the ASBMB career center

Get the latest from ASBMB Today

Enter your email address, and we’ll send you a weekly email with recent articles, interviews and more.

Latest in Careers

Careers highlights or most popular articles

Learn, reflect and lead
Annual Meeting

Learn, reflect and lead

Sept. 26, 2022

This symposium, Educational Professional Development, will be part of #DiscoverBMB 2023 in March.

Calendar of events, awards and opportunities
Announcement

Calendar of events, awards and opportunities

Sept. 25, 2022

Happening this week: The #DiscoverBMB abstract and travel-award system opens! Fast-track your abstract and get a decision in two weeks.

Purpose and gratitude boost academic engagement
Education

Purpose and gratitude boost academic engagement

Sept. 24, 2022

“This study adds to a growing body of research that suggests having a deep sense of life purpose is important for people’s well-being, success and ability to cope with challenging life situations,” the author writes.

Following a passion for science — away from academia
Jobs

Following a passion for science — away from academia

Sept. 23, 2022

Brittany Leigh does public relations for life science companies.

What is better for your career than a publication? A preprint.
Essay

What is better for your career than a publication? A preprint.

Sept. 22, 2022

“Depositing a paper outside of an academic journal allows an author to start promoting the work immediately,” Ken Hallenbeck writes.

Computation is the new experiment
Annual Meeting

Computation is the new experiment

Sept. 20, 2022

This symposium, Artificial Intelligence and Machine Learning in Structural Biology, Drug Design and Systems Biology. will be part of #DiscoverBMB 2023 in March.