Open Letters

An open letter from
a not-so-good Brahmin boy

Akshat Sharma
By Akshat Sharma
Feb. 1, 2014

Dear Professor S.,
 
I hope this finds you well.
 
I am at a recruitment weekend for prospective Ph.D.s in the immunological and microbiological sciences. Having received my undergraduate degree in biotechnology and having followed it up with an M.S. in microbiology with a strong immunology focus, I always have known people forging ahead in academia, getting Ph.D.s, publishing, running labs, sparring with fellow scientists, attending conferences and so forth. This is all I have ever known, and I have yearned to join their number.
 
Why? Well, because I love science. More specifically, I love immunology. I am awed by the subterfuges that pathogens employ and the countersubterfuges of the immunocytes: The immune response is a devastating romance set to the stylings of a cytokine signaling suite.
 
And me? I will be the agent who discovers those symphonies, those diamonds in the rough that play in an anonymous niche of the cell, and publish papers about them so that the world will know and laud my genius and that of my findings. Of course this will happen. This is what I am meant to be. It is something I always have known.
 
I remember coming out of the closet. I remember it because it was the most excruciating experience I have had so far in life and also because I was the last one to know. It appeared that my friends always had known. It was evident from their lack of surprise and, for some, a sense of understanding and closure. I wish they could have given me this closure: I wish I hadn’t had to go hunting for it within. But how could they? This was meant to be my journey. That I was to embark on this journey was a fact that I was the last to know.
 
Today, as I sat in the unusually cold Memphis air deep in conversation with a scientist, a product of our home lab, I found myself gingerly opening the door of yet another closet: For, you see, I am a closeted writer. And, like before, I was the last to know.
 
My lab mates, it appeared, always had known. The scientist in question always had known. She reminded me of the essays I had written for an immunology course she’d taught and of how much she had enjoyed the way I drew parallels between the events in “Richard III” and the pathogenesis of HIV. She told me to look again at all the blog posts that I’d written and think hard about what I was throwing away.
 
Was I truly throwing something away? Really? This life is as awkward and undecided as someone meandering around an airport in Amsterdam, unsure of which connecting flight to take to get him home. So many revelations, and, as always, I am the last one to know.
 
In truth, Professor S., I always have known this: The times when I wondered, at the end of every American literature course I surreptitiously took as an undergrad, if I should change majors, now feel just like the times when I’d catch a handsome, ashen boy’s eye and wonder what if but then retract because I was a Good Brahmin Boy.
 
I always have known that Good Brahmin Boys do not kiss other boys. Good Brahmin Boys ensure futures of procreations and publications I am not a Good Brahmin Boy. I cannot pretend to be one anymore, because that would be akin to living a Richard Yates novel.
 
I felt liberated today as I confess to myself that I am not like them. My mind is not the kind that does the dogged, logical thing that they do as they plan experiments, do experiments and launch into a “Hunger Games”-esque race for grant money.
 
I always have known I am not a shark. I am not a shark, and that is OK, because I’d rather create. I am at my happiest when I write, more so when I write about immunology and infectious disease.
 
It was with these revelations that I decided to fill out this application to your scientific journalism program only to discover that the deadline is tomorrow. Well, today. And here I am: the last one to know. Figures.
 
I remain yours sincerely,
Akshat Sharma

Enjoy reading ASBMB Today?

Become a member to receive the print edition four times a year and the digital edition monthly.

Learn more
Akshat Sharma
Akshat Sharma

Akshat Sharma was a graduate student at the University of Wisconsin-Madison when he wrote this article.

Get the latest from ASBMB Today

Enter your email address, and we’ll send you a weekly email with recent articles, interviews and more.

Latest in Opinions

Opinions highlights or most popular articles

Learning can be fun: Gaming anatomy and physiology
Essay

Learning can be fun: Gaming anatomy and physiology

May 8, 2026

Instructors explore how gamification and active learning transform student engagement and retention. They convey how emotion, interaction and design can make even rigorous subjects more effective and memorable.

Mentorship and uncertainty: Lessons from Telemachus
Essay

Mentorship and uncertainty: Lessons from Telemachus

April 30, 2026

A biochemistry educator reflects on mentorship through the Greek story of Telemachus, showing how embracing uncertainty, failure and curiosity can transform teaching.

Embracing the twists and turns along the educator pathway
Essay

Embracing the twists and turns along the educator pathway

April 30, 2026

A biochemistry educator reflects on the challenges of early faculty life, describing how evidence-based teaching, cross-disciplinary collaboration and classroom challenges shaped her growth.

Redesigning with students in mind
Essay

Redesigning with students in mind

April 29, 2026

Assistant professor reflects on how the shift to online teaching revealed gaps in points-based grading and led to a redesign centered on transparency and student growth.

Teaching beyond information transfer
Essay

Teaching beyond information transfer

April 29, 2026

Educator reflects on moving beyond lectures to create a biochemistry classroom centered on engagement, transparency and student ownership, showing how small shifts like “student hours” and active learning can transform understanding.

Mayday! Lessons from cellular dysfunction and group work dynamics
Essay

Mayday! Lessons from cellular dysfunction and group work dynamics

April 28, 2026

An upper-level biology course revealed that strong science doesn’t guarantee strong teamwork. One instructor shares how failed group dynamics reshaped their approach, leading to more structured, collaborative and effective student learning.