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From the journals: JLR
What activates T cells in psoriasis? Lysosomal acid lipase in liver disease. A controlled diet targets heart disease risk. Read about these recent papers.
Inflammation and diabetic kidney disease: Why mitochondria matter
Restoring function to a specific organelle could mitigate disease progression.
Finasteride may cut heart disease risk
Research on common hair loss and prostate drug shows results in men and mice.
Researchers get to the bottom of noninvasive gut tests
Mucus contains vital data to help address diseases such as inflammatory bowel disease and colon cancer.
Drugs of the future will be easier and faster to make, thanks to mRNA
But researchers still have to work out a few remaining kinks.
Mouse model may help explain, treat infertility
Discovering how sperm begin the fertilization process could also identify new targets for nonhormonal contraceptives.
Breaking down fat byproducts could lead to healthier aging
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AI harnesses tumor genetics to predict treatment response
Many paths lead to cancer resistance; artificial intelligence can decode them all simultaneously.
Progression of ALS linked to a membrane and an enzyme
Diminished activities of the enzyme TBK1 in mitochondrial-associated membrane reduces motor neurons’ tolerance to stressors, a causative factor in the disease.
From the journals: JLR
Breaking down atherosclerotic plaque. Location matters in liver disease. A lipidomic profile drives liver disease. Read about recent papers on these topics.
Sibling study reveals mechanism for genetic disease
Using proteomics experiments, researchers found that old proteins pile up in the mitochondria of people with a form of adult-onset muscular dystrophy.
Why don’t fruit bats get diabetes?
New understanding of how these animals have adapted to a high-sugar diet could lead to treatments for people.
The remaining frontiers in fighting hepatitis C
Charles Rice, whose work was key to finding treatments for this life-threatening virus, discusses the scientific journey and challenges that persist.
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