Motifs, modules, networks: Assembly and organization of regulatory signaling systems

July 11–14, 2023
Bolger Center, Potomac, Md.

Our understanding of how cellular signaling networks are organized has evolved substantially in recent years. Namely, the myriad components of signaling networks — receptors, signaling enzymes such as phosphatases and kinases, substrates and scaffolding proteins — often assemble through highly dynamic interactions involving intrinsically disordered regions and short linear sequence motifs (SLiMs). These dynamic interactions allow for rapid responses to signaling inputs and dictate systems-level properties of signaling networks. Understanding SLiM-mediated interactions has made it possible to define “substratomes” of signaling enzymes as well as interaction networks that provide novel insights into signaling platforms and cellular networking mechanisms.

This interdisciplinary conference will bring together researchers in structural biology, biochemistry, computational biology and proteomics who investigate cellular signaling networks and leverage these insights into the development of new therapeutic strategies.


Wolfgang Peti
Wolfgang Peti
University of Connecticut Health Center
Benjamin Turk
Benjamin Turk
Yale School of Medicine
Arminja Kettenbach
Arminja Kettenbach
Dartmouth Geisel School of Medicine

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Conference information

  • Conference will begin around 4 p.m. on July 11.
  • Conference will conclude around 2 p.m. on July 14.

Registration and abstract information

  • There is no onsite registration, all attendees must be registered prior to arriving at the conference.
  • Registration for the conference is required at the time of abstract submission.
  • Please reach out to if you have questions.

Getting to the Bolger Center


Getting from the airports to the Bolger Center

All attendees are responsible for their own transportation. There will not be a shuttle provided to/from the airports/Bolger Center.


All individuals traveling from outside of the United States should apply for a visa as soon as possible and at least four to five months prior to their date of travel.

Please do not wait until you receive your registration confirmation before applying for a visa. We encourage you to apply for your visa right away if you are considering attending to avoid delays and longer than anticipated wait times.

All visitors traveling to the U.S. from visa waiver countries (Europe, Japan, Australia, etc.) must meet all requirements of the program. Find more information on the Electronic System for Travel Authorization (ESTA) and a list of visa waiver countries.