Motifs, modules, networks: Assembly and organization of regulatory signaling systems
July 11–14, 2023
Bolger Center, Potomac, Md.
Our understanding of how cellular signaling networks are organized has evolved substantially in recent years. Namely, the myriad components of signaling networks — receptors, signaling enzymes such as phosphatases and kinases, substrates and scaffolding proteins — often assemble through highly dynamic interactions involving intrinsically disordered regions and short linear sequence motifs (SLiMs). These dynamic interactions allow for rapid responses to signaling inputs and dictate systems-level properties of signaling networks. Understanding SLiM-mediated interactions has made it possible to define “substratomes” of signaling enzymes as well as interaction networks that provide novel insights into signaling platforms and cellular networking mechanisms.
This interdisciplinary conference will bring together researchers in structural biology, biochemistry, computational biology and proteomics who investigate cellular signaling networks and leverage these insights into the development of new therapeutic strategies.
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- Madan Babu, St. Jude Research Hospital
- Norman Davey, Institute of Cancer Research
- Ranajeet Ghose, City College of New York
- Anne-Claude Gingras, Lunenfeld–Tanenbaum Research Institute
- Ylva Ivarsson, Uppsala University
- Amy Keating, Massachusetts Institute of Technology
- Evangelia Petsalaki, EMBL–European Bioinformatics Institute
- Jesse Rinehart, Yale University
- John Scott, University of Washington
- Neel Shah, Columbia University
- Michael Yaffe, Massachusetts Institute of Technology
- Jin Zhang, University of California, San Diego
- Conference will begin around 4 p.m. on July 11.
- Conference will conclude around 2 p.m. on July 14.
Registration and abstract information
- There is no onsite registration, all attendees must be registered prior to arriving at the conference.
- Registration for the conference is required at the time of abstract submission.
- Please reach out to firstname.lastname@example.org if you have questions.
Getting to the Bolger Center
- Reagan National Airport (DCA) — 19.6 miles
- Dulles International Airport (IAD) — 24.5 miles
- Baltimore/Washington International Thurgood Marshall Airport (BWI) — 39.8 miles
Getting from the airports to the Bolger Center
All attendees are responsible for their own transportation. There will not be a shuttle provided to/from the airports/Bolger Center.
All individuals traveling from outside of the United States should apply for a visa as soon as possible and at least four to five months prior to their date of travel.
- The most up-to-date information about traveling to the U.S. can be found at the U.S. State Department website.
- Scientists visiting the U.S. may find helpful information at the National Academies of Sciences website.
- Find visa appointment wait times here.
Please do not wait until you receive your registration confirmation before applying for a visa. We encourage you to apply for your visa right away if you are considering attending to avoid delays and longer than anticipated wait times.
All visitors traveling to the U.S. from visa waiver countries (Europe, Japan, Australia, etc.) must meet all requirements of the program. Find more information on the Electronic System for Travel Authorization (ESTA) and a list of visa waiver countries.