Motifs, modules, networks: Assembly and organization of regulatory signaling systems

July 11–14, 2023
Bolger Center, Potomac, Md.

Our understanding of how cellular signaling networks are organized has evolved substantially in recent years. Namely, the myriad components of signaling networks — receptors, signaling enzymes such as phosphatases and kinases, substrates and scaffolding proteins — often assemble through highly dynamic interactions involving intrinsically disordered regions and short linear sequence motifs (SLiMs). These dynamic interactions allow for rapid responses to signaling inputs and dictate systems-level properties of signaling networks. Understanding SLiM-mediated interactions has made it possible to define “substratomes” of signaling enzymes as well as interaction networks that provide novel insights into signaling platforms and cellular networking mechanisms.

This interdisciplinary conference will bring together researchers in structural biology, biochemistry, computational biology and proteomics who investigate cellular signaling networks and leverage these insights into the development of new therapeutic strategies.

Organizers

Wolfgang Peti
Wolfgang Peti
University of Connecticut Health Center
Arminja Kettenbach
Arminja Kettenbach
Dartmouth Geisel School of Medicine
Benjamin Turk
Benjamin Turk
Yale School of Medicine

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Speakers

  • Madan Babu, St. Jude Research Hospital
  • Norman Davey, Institute of Cancer Research
  • Ranajeet Ghose, City College of New York
  • Anne-Claude Gingras, Lunenfeld–Tanenbaum Research Institute
  • Ylva Ivarsson, Uppsala University
  • Amy Keating, Massachusetts Institute of Technology
  • Evangelia Petsalaki, EMBL–European Bioinformatics Institute
  • Jesse Rinehart, Yale University
  • John Scott, University of Washington
  • Neel Shah, Columbia University
  • Michael Yaffe, Massachusetts Institute of Technology
  • Jin Zhang, University of California, San Diego

Sponsors

Important dates

May 10 Early registration deadline*
May 10 Abstract submission deadline for oral and poster (authors are required to register for the conference upon submission of abstract)
June 12 Deadline for cancelations/refunds (no refunds after this date)
June 12 Regular registration deadline*

*Registration and housing are on a first-come, first-served basis and will remain open until capacity is reached. This may mean that the conference registration closes before the officially posted registration deadline. To secure your spot at the conference we encourage you to register early.

Conference information

  • Conference will begin around 4 p.m. on July 11.
  • Conference will conclude around 2 p.m. on July 14.

Registration and abstracts

  • There is no onsite registration, all attendees must be registered prior to arriving at the conference.
  • Registration for the conference is required at the time of abstract submission.
  • Please reach out to meetings@asbmb.org if you have questions.

Health and safety

  • Mask-wearing and other health and safety measures will be determined based on local, state and venue guidelines and will be communicated to attendees prior to the conference.

Abstracts

Abstracts will be reviewed and selected for short talks. Those not selected may be programmed as posters. Oral programming notifications, including the time and date of the presentation, will be sent via email by Friday, May 26, 2023.

Submit abstract

Abstract submission guidelines

  • Abstract title field allows 200 characters maximum.
  • Abstract body field allows for 350 words maximum (not including authors and affiliations).
  • Text may be typed or copied and pasted into the abstract title and body fields.

Presentation requirement

All speakers and poster presenters are required to present in person at the scheduled date and time of their sessions. If you have submitted an abstract or are planning to submit an abstract we encourage you to register at the time of abstract submission because space is limited. Registration is not guaranteed.

How to submit an abstract

ASBMB members
  1. Click “Submit Abstract" button.
  2. Enter the email address associated with your ASBMB member profile. (Don't remember the email associated with your member record? Contact membership@asbmb.org before proceeding.)
  3. Once your email address is validated by the system, enter the password associated with your ASBMB member profile. (Don't remember your password? Click "Forgot your password?" to have your password emailed to you. Check your junk mail and spam filter if you do not see the reminder email in your inbox.)
  4. Do NOT create a new profile if you do not remember either the email address or the password associated with your ASBMB membership account. Contact membership@asbmb.org and request this information prior to submitting.
  5. Select the, "Submit and Continue" button at the bottom of the page.
  6. Select the "Submit Abstract" button to enter your abstract submission.
Non-members
  1. Click “Submit Abstract" button.
  2. Click the "Create an ASBMB Account" button to set up your user profile.
  3. Complete the profile fields and select the, "Submit and Continue" button at the bottom of the page.
  4. Select the "Submit Abstract" button to enter your abstract submission.

Registration

ASBMB members will receive a $50 discount on their registration fee which will be applied during checkout.

Not a member? Join the ASBMB and save!

 
  Early registration
(by May 10)
Regular registration
(by June 12)
PI/regular academics, industry or equivalent
single, private room
$1,750 $1,800
PI/regular academics, industry or equivalent
double, shared room
$1,350 $1,400
PI/regular academics, industry or equivalent
commuter, no lodging
$700 $750
Trainee, graduate student, postdoc or equivalent
single, private room
$1,350 $1,400
Trainee, graduate student, postdoc or equivalent
double, shared room
$850 $900
Trainee, graduate student, postdoc or equivalent
commuter, no lodging
$400 $450
 

What’s included

The full conference package includes:

  • All scientific sessions, poster sessions, and meeting materials.
  • Three nights lodging at the Bolger Center (check in on July 11 and check out on July 14)
  • The following meals are included in your conference registration fee:
    • Tuesday, July 11: Dinner
    • Wednesday, July 12: Breakfast, lunch, dinner
    • Thursday, July 13: Breakfast, lunch, dinner
    • Friday, July 14: Breakfast and lunch

Note: Lodging is not included in the commuter registration rates.

Registration changes

Registration changes will be accepted as space allows until Monday, June 12, 2023, and can be made by contacting meetings@asbmb.org.

Cancelation policy

Cancelations received in writing on or before Monday, June 12, 2023, are subject to a $100 processing fee. No refunds will be issued for cancellations after June 12, due to final guarantee commitments. 


Getting to the Bolger Center

Airports

Getting from the airports to the Bolger Center

All attendees are responsible for their own transportation. There will not be a shuttle provided to/from the airports/Bolger Center.

Visas

All individuals traveling from outside of the United States should apply for a visa as soon as possible and at least four to five months prior to their date of travel.

Please do not wait until you receive your registration confirmation before applying for a visa. We encourage you to apply for your visa right away if you are considering attending to avoid delays and longer than anticipated wait times.

All visitors traveling to the U.S. from visa waiver countries must meet all requirements of the program. Find more information on the Electronic System for Travel Authorization (ESTA) and a list of visa waiver countries.


Tentative program schedule

Tuesday July 11
Wednesday July 12
Thursday July 13
Friday July 14

Tuesday agenda

4:00 PM - 5:00 PM

Badge pickup

7:00 PM - 7:15 PM

Welcome and opening remarks by the organizers

7:15 PM - 9:00 PM

Session I: New approaches to short linear motif discovery

9:00 PM - 10:00 PM

Pony express discussions

Wednesday agenda

8:30 AM - 11:45 AM

Session II: Biophysics of linear motif function

1:30 PM - 3:30 PM

Session III: Protein interaction networks

3:30 PM - 4:00 PM

Break

4:00 PM - 5:30 PM

Poster session I

7:00 PM - 9:00 PM

Session IV: Compartmentalization of cellular signaling

9:00 PM - 10:00 PM

Pony express discussions

Thursday agenda

8:30 AM - 11:45 AM

Session V: Computational modeling of signaling networks

1:30 PM - 3:30 PM

Session VI: Regulation of short linear motif interactions

3:30 PM - 4:00 PM

Break

4:00 PM - 5:30 PM

Poster session II

7:00 PM - 10:00 PM

Pony express discussions

Friday agenda

8:30 AM - 11:45 AM

Session VII: Control of essential biological processes by SLiM Modulation