Sept. 28 – Oct. 2, 2022 | Seattle

The interplay between epigenetic regulation and genome stability

The interplay between epigenetic regulation and genome stability
Sept. 28 – Oct. 2, 2022 | Sheraton Grand, Seattle

It is clear that epigenetic and chromatin states impact DNA replication and DNA repair, two key processes critical for maintaining genome integrity. However, most meetings on epigenetics and chromatin focus on transcription, while most meetings on genome integrity include little attention to epigenetics and chromatin. The goal of this conference is to bring together scientists who are interested in epigenetic regulation and genome integrity for discussion and interactions. This conference will bridge this gap to link researchers who are interested in epigenetic regulations and chromatin with those who are interested in genome integrity.

In addition to the scientific focus, we will promote interactions between two societies, the American Society for Biochemistry and Molecular Biology and the Biophysical Society of China. The first joint conference of the two societies was held in China in 2019 and was very successful, and we look forward to holding the conference in the U.S. in 2022.

The major focus of this meeting will be the dynamic interplay among chromatin, including histone modifications and high-order chromatin structure, and processes related to genome integrity, including DNA replication, repair and damage response. Moreover, we will determine how the interplay goes awry in cancer and aging cells.

Important dates

Aug. 2 Abstract submission deadline
Aug. 2 Early registration deadline
Aug. 29 Regular registration deadline

Travel grants

We are excited to offer a limited number opportunities to help defray the costs of travel for early career and underrepresented minority scientists to present research at the conference. We are committed to equity, inclusion and diversity and strongly encourage applications from individuals who belong to groups traditionally underrepresented in science. For more information and to apply, please visit our travel grant application page.

Sponsorship opportunities

The conference is offering a variety of sponsorship opportunities for your organization to optimize your visibility to attendees. Learn about sponsorship opportunities.


Jessica Tyler Cornell University
Zhiguo Zhang Columbia University Irving Medical Center
Guohong Li Institute of Biophysics, Chinese Academy of Sciences

Keynote speakers

Geneviève Almouzni Institut Curie
John Diffley Francis Crick Institute

COVID-19 vaccination requirement

For the health and safety of attendees, COVID-19 vaccination is required for anyone attending this conference. Mask-wearing and other requirements will be based on state and local guidelines and will be communicated with attendees before the start of the event.

Access the latest COVID-19 guidelines from:



ASBMB members will receive a $50 discount on their registration fee which will be applied during registration check-out.

Not a member? Join the ASBMB and save!

  Early registration
(by Aug. 2)
Regular registration
(by Aug. 29)
Trainee: Graduate student or postdoc (no lodging) $325 $375
PI, industry or equivalent (no lodging) $625 $675

What’s included

The registration rates include:

  • All scientific sessions, poster sessions and meeting materials.
  • Morning/afternoon refreshments on meeting days.
  • Dinner on final evening of the conference.

Note: Lodging is not included in the registration rates.

Registration changes

Registration changes will be accepted as space allows until Aug. 30, 2022, and can be made by contacting

Cancellation policy

Cancellations received in writing on or before Aug. 30, 2022, are subject to a $100 processing fee. No refunds will be issued for cancellations after Aug. 30 due to final guarantee commitments. Email and attach a copy of your meeting registration receipt/paid invoice.

Hotel accommodations

Participants are responsible for securing and paying for their own housing arrangements. A discounted rate of $169 + tax per night has been arranged at the Sheraton Grand Seattle.

Sheraton Grand Seattle
1400 Sixth Avenue
Seattle, WA 98101



By phone: Call 206-447-5547 and ask for the ASBMB Epigenetics Conference 2022 group rate. Rooms will be available at the group rate until Monday, Aug. 29, or the room block sells out, whichever comes first.


Abstract submission deadline: Aug. 2.

Submit abstract

Abstracts will be reviewed and selected for short talks and poster presentations. Programming notifications (for both oral and poster presentations) including time and date of presentation, will be sent via email by Aug. 11. Three poster presenters will also be selected during the meeting to conduct short talks (10 minute talks, 5 minute Q&A) on Sunday, Oct. 2.

Abstract submission guidelines

  • Abstract title field allows 200 characters maximum.
  • Abstract body field allows 350 words maximum (not including authors and affiliations).
  • Text may be typed or copied and pasted into the abstract title and body fields.

Presentation requirements

All speakers and poster presenters are required to present in-person at the scheduled date and time of their sessions.

How to submit an abstract

ASBMB members
  1. Click “Submit Abstract" button.
  2. Enter the email address associated with your ASBMB member profile. (Don't remember the email associated with your member record? Contact before proceeding.)
  3. Once your email address is validated by the system, enter the password associated with your ASBMB member profile. (Don't remember your password? Click "Forgot your password?" to have your password emailed to you. Check your junk mail and spam filter if you do not see the reminder email in your inbox.)
  4. Do NOT create a new profile if you do not remember either the email address or the password associated with your ASBMB membership account. Contact and request this information prior to submitting.
  5. Select the, "Submit and Continue" button at the bottom of the page.
  6. Select the "Submit Abstract" button to enter your abstract submission.
  1. Click “Submit Abstract" button.
  2. Click the "Create an ASBMB Account" button to set up your user profile.
  3. Complete the profile fields and select the, "Submit and Continue" button at the bottom of the page.
  4. Select the "Submit Abstract" button to enter your abstract submission.

Program schedule

Wednesday September 28
Thursday September 29
Friday September 30
Saturday October 1
Sunday October 2

Wednesday agenda

7:30 PM - 8:30 PM

Keynote address I

Investigating how DNA replication initiates in eukaryotes
John Diffley, Francis Crick Institute
8:30 PM - 10:00 PM

Session 1: Replicating the epigenome

3 short talks selected from abstracts
Reconstituting replication on chromatin templates
Dirk Remus, Memorial Sloan Kettering Cancer Center

Thursday agenda

9:00 AM - 12:30 PM

Session 2: Repairing the epigenome

Charting the response to DNA damage
Daniel Durocher, University of Toronto
3 short talks selected from abstracts
2 short talks selected from abstracts
Phase separation drives genome stability
Evi Soutoglou, University of Sussex
2:30 PM - 6:00 PM

Session 3: Modifying the epigenome to maintain genome integrity and its dysregulation in cancer

Onco-histone mutations reprogram cancer epigenomes
Zhiguo Zhang, Columbia University School of Medicine
3 short talks selected from abstracts 
Short talk: Specificity of histone acetylation antibodies and methods for their detection
Michael Keogh, EpiCypher
Short talk selected from abstracts
Chromosome instability triggers relocalization in cancer
Hongtao Yu, Westlake University
8:00 PM - 10:00 PM

Poster session 1

Friday agenda

9:00 AM - 12:30 PM

Session 4: Chromosome dynamics during genome maintenance

Visualizing chromatin within cells
Susan Gasser, Friedrich Miescher Institute for Biomedical Research
3 short talks selected from abstracts
2 short talks selected from abstracts
Highways for repair of heterochromatic DNA breaks
Irene Chiolo, University of Southern California
8:00 PM - 10:00 PM

Poster session 2

Saturday agenda

9:00 AM - 12:00 PM

Session 6: Genome maintenance during growth, development and carcinogenesis

DOT1L in leukemogenenic activity
Ruiming Xu, Institute of Biophysics
2 short talks selected from abstracts
2 short talks selected from abstracts
Genome-wide mapping of protein–DNA interactions
Steven Henikoff, Fred Hutchinson Cancer Research Center
1:00 PM - 2:00 PM

Panel discussion: Career choices and getting started

2:00 PM - 5:45 PM

Session 7: Chromatin remodeling to maintain genome integrity

Structural analysis of the replicating epigenome
Guohong Li, Institute of Biophysics
2 short talks selected from abstracts
Talk title TBD
Toshi Tsukiyama, Fred Hutchinson Cancer Center
2 short talks selected from abstracts
Studying DNA repair in chromatin and its link to human disease
Haico van Attikum, Leiden University

Sunday agenda

9:00 AM - 12:15 PM

Session 8: Nucleosome assembly during DNA replication and repair

Epigenetic regulation of DNA repair
Jessica Tyler, Weill Cornell Medicine
3 poster prize-winner talks
Chromatin assembly after DNA replication
Qing Li, Peking University
12:45 PM - 1:45 PM

Keynote address II

Regulation of chromatin organization
Geneviève Almouzni, Institut Curie

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