2022 ASBMB Annual Meeting

Sessions

Deepen your knowledge of significant research trends during daily sessions curated by pioneers and innovators.

Education and professional development

Organizers:

  • Victoria Moore, Elon University
  • Erin Sayer, University of Nebraska–Lincoln

Inclusive and civil communication

Session Chair: Erin Sayer, University of Nebraska–Lincoln

  • Developing a collaborative environment to facilitate inclusive departmental communication
    Todd Weaver, University of Wisconsin–La Crosse
  • Creative strategies to perform an inclusive faculty search
    Anita Corbett, Emory University
  • Creative approaches to perform an inclusive faculty search
    Wendy Gilbert, Yale University

Strategies for assessment in higher education

Session Chair: Victoria Moore, Elon University

  • Peer collaboration and review: A guide to iterative improvement in learning
    Dan Bernstein, University of Kansas
  • What makes a competitive applicant? Assessing students for graduate/professional school applications
    Erin Sayer, University of Nebraska–Lincoln
  • Developing BMB assessment questions for use in the undergraduate classroom
    Victoria Moore, Elon University
EPD
Magazine

Responding to the needs of educators post-COVID-19

This 2022 ASBMB annual meeting session is powered by forward thinking.

Enzymology

Organizers:

  • Tadhg Begley, Texas A&M University
  • Catherine Drennan, Massachusetts Institute of Technology

Enzyme structure and function

Session chair: Catherine Drennan, Massachusetts Institute of Technology

  • Repairing enzymes using spare parts
    Catherine Drennan, Massachusetts Institute of Technology
  • Machinery in motion: New insights into mitochondrial proteostasis
    Gabriel Lander, Scripps Research Institute
  • Structural biology of natural product biosynthetic enzymes
    Janet Smith, University of Michigan
  • An aerobic strategy for C-H bond functionalization
    Jennifer Bridwell-Rabb, University of Michigan

Frontiers in enzymology

Session chair: Tadhg Begley, Texas A&M University

  • Riboflavin catabolism: The destruction of an icon
    Tadhg Begley, Texas A&M University
  • Correlated motions in enzymes
    Nozomi Ando, Cornell University
  • Nickel pincer nucleotide: biosynthesis and function
    Robert Hausinger, Michigan State University
  • Bacterial biosynthesis of natural products
    Katherine Ryan, University of British Columbia

Radical SAM enzymology

Session chair: Catherine Drennan, Massachusetts Institute of Technology

  • Radical SAMs and the vast unexplored chemistry of RiPP natural products
    Douglas Mitchell, University of Illinois Urbana-Champaign
  • The biosynthesis of lipoic acid: A saga of death, destruction and rebirth
    Squire Booker, Pennsylvania State University
  • Unraveling the secrets of radical SAM mechanisms
    Joan Broderick, Montana State University
  • How do aerobic organisms solve the oxygen sensitivity problem of [4Fe-4S] in radical SAM enzymes?
    Hening Lin, Cornell University; Howard Hughes Medical Institute
Enzymology
Magazine

Enzymes show off new moves

This 2022 ASBMB annual meeting session is powered by proteins, cofactors and coffee.

Glycobiology

Organizers:

  • Valerie Weaver, University of California, San Francisco
  • Stephen Withers, University of British Columbia

Structure/function and manipulation and imaging of the glycocalyx

Session chair: Stephen Withers, University of British Columbia

  • Nanoscale physical biology of the cellular glycocalyx
    Matthew J. Paszek, Cornell University
  • MALDI imaging mass spectrometry mapping of the glycocalyx
    Richard R. Drake, Medical University of South Carolina
  • Genetic and small molecule strategies to edit the glycocalyx
    Sriram Neelamegham, State University of New York at Buffalo
  • Enzymatic removal of cell surface antigens as a route towards universal O type blood and organs
    Stephen Withers, University of British Columbia

Glycans in cell biology

Session chair: Susan Bellis, University of Alabama at Birmingham

  • Hypersialylation of tumor cells promotes pancreatic cancer progression
    Susan Bellis, University of Alabama at Birmingham
  • Receptor N-glycosylation links metabolism with signaling
    James Dennis, Lunenfeld Tanenbaum Research Institute
  • Modeling the mucinous glycocalyx to unravel receptor pattern recognition by influenza A viruses
    Kamil Godula, University of California, San Diego
  • Cell surface glycan engineering reveals that matriglycan alone can recapitulate dystroglycan binding and function
    Geert-Jan Boons, University of Georgia

Physiological impact of glycans in tissue homeostasis and disease — focus on cell–ECM interactions

Session chair: Valerie Weaver, University of California, San Francisco

  • The glycocalyx in tumor progression and metastasis
    Valerie Weaver, University of California, San Francisco
  • The heparaase/syndecan-1 axis in cancer progression
    Ralph D. Sanderson, University of Alabama at Birmingham
  • Reprogramming T cells to target glycans and overcome glycan-mediated immunosuppression for cancer therapy
    Avery Posey, University of Pennsylvania
  • Orchestrated intragranular restructuring of mucins during secretory granule maturation 
    Kelly Ten Hagen, National Institute of Dental and Craniofacial Research
Glycobiology
Magazine

Sugar coating is, in fact, important

This 2022 ASBMB annual meeting session is powered by interdisciplinary science with a sweet touch.

Membranes/Lipids

Organizers:

  • Tamas Balla, National Institutes of Health
  • Lois Weisman, University of Michigan

Organizing signaling domains through non-vesicular lipid transfer and membrane contacts

Session chair: Orna Cohen-Fix, National Institute of Diabetes and Digestive and Kidney Diseases

  • Regulation of PIP2 homeostasis at ER-plasma membrane contacts by Nir proteins
    Jen Liou, University of Texas Southwestern Medical Center
  • Roles for inter-organelle contacts in organizing metabolism
    W. Mike Henne, University of Texas Southwestern Medical Center
  • Systematic analysis of membrane contact sites
    Maya Schuldiner, Weizmann Institute of Science
  • Novel pathways of intracellular membrane lipid transport and neurodegenerative diseases
    Pietro De Camilli, Yale University School of Medicine; Howard Hughes Medical Institute

Novel approaches to understand membrane composition and structure

Session chair: Lois Weisman, University of Michigan

  • Chemical tools for understanding phospholipase D signaling
    Jeremy Baskin, Cornell University
  • Control of the cellular lipid landscape by inositol lipids
    Tamas Balla, National Institutes of Health
  • Volume electron microscopy analysis reveals a new type of membrane junction required for mixing of parental genomes after fertilization
    Orna Cohen-Fix, National Institute of Diabetes and Digestive and Kidney Diseases
  • Automatic whole cell organelle segmentation in volumetric electron microscopy
    Aubrey Weigel, Howard Hughes Medical Institute Janelia Research Campus

Membrane dynamics in trafficking and signaling

Session chair: Tamas Balla, National Institutes of Health

  • Regulation of membrane dynamics via phosphoinositide signaling cascades 
    Lois Weisman, University of Michigan
  • Novel mechanisms in phosphoinositide turnover
    Raghu Padinjat, National Centre for Biological Sciences
  • Regulation of COPII dynamics in development and disease
    Anjon Audhya, University of Wisconsin-Madison
  • Intracellular trafficking during neutrophil chemotaxis
    Carole Parent, University of Michigan
Diversity, equity and inclusion
Magazine

Join the conversation on how cells talk to themselves and to each other

A 2022 annual meeting session on membranes and lipids.

Metabolism

Organizers:

  • Scott Dixon, Stanford University
  • Marian Walhout, University of Massachusetts Medical School

Metabolism and model systems

Session chair: Marian Walhout, University of Massachusetts Medical School

  • Interplay between metabolism and gene expression
    Marian Walhout, University of Massachusetts Medical School
  • Identifying toxic metabolites and their roles in disease
    Dohoon Kim, University of Massachusetts Medical School
  • Transcriptional regulation of primary and specialized metabolism
    Siobhan Brady, University of California, Davis
  • Interorgan crosstalk and metabolism regulation in Drosophila
    Norbert Perrimon, Harvard University

Complex metabolic interactions

Session chair: Stavroula Hatzios, Yale University

  • Metabolic adaptation to oxidative stress at the host-microbe interface
    Stavroula Hatzios, Yale University
  • Deconvoluting host-gut microbiota co-metabolism
    Pamela Chang, Cornell University
  • The tiny pharmacists within: how the human gut microbiome impacts drug metabolism and disposition
    Peter Turnbaugh, University of California, San Francisco
  • Metabolic outliers in human disease
    Ralph DeBerardinis, University of Texas Southwestern Medical center

Metabolic mechanisms

Session chair: Scott Dixon, Stanford University

  • Lipid metabolism and ferroptosis
    Scott Dixon, Stanford University
  • Too much and never enough: Synthetic excess and metabolic inefficiency of aneuploidy in tumorigenesis
    Emma Watson, Harvard Medical School
  • Uncovering conditional vulnerabilities in cancer
    Jason Cantor, University of Wisconsin
  • The genetics of tumor suppression by p53
    Maureen Murphy, Wistar Institute
Metabolism
Magazine

Connecting metabolism to development, disease and therapy

This 2022 ASBMB annual meeting session is powered by ATP. What else?

Protein machines and disorder

Organizers:

  • Martin Beck, Max Planck Institute of Biophysics
  • Tanja Mittag, St. Jude Children’s Research Hospital

Macromolecular complexes

Session chair: Martin Beck, Max Planck Institute of Biophysics

  • In situ structural analysis of the nuclear pore complex
    Martin Beck, Max Planck Institute of Biophysics
  • Molecular-scale structure of a high-curvature membrane
    Adam Frost, University of California, San Francisco
  • Structure and function of DNA transposition assemblies
    Orsolya Barabas, University of Geneva
  • Structural adventures in bacterial protein secretion and motility
    Susan Lea, National Institutes of Health

Phase transitions of structured complexes and cellular machinery

Session chair: Edward Lemke, Johannes Gutenberg University; Institute of Molecular Biolog

  • Building the microtubule cytoskeleton via phase transitions
    Sabine Petry, Princeton University
  • Structured and disordered proteins collaborate to drive membrane remodeling
    Jeanne Stachowiak, University of Texas at Austin
  • Phase separation shapes form and function of the nucleolus
    Richard Kriwacki, St. Jude Children’s Research Hospital
  • Decoding plasticity of the dark proteome
    Edward Lemke, Johannes Gutenberg University; Institute of Molecular Biology

Physiological and pathological phase transitions of disordered proteins

Session chair: Tanja Mittag, St. Jude Children’s Research Hospital

  • Phase behavior of intrinsically disordered prion-like domains
    Tanja Mittag, St. Jude Children’s Research Hospital
  • Regulation of translation and deadenylation via biomolecular condensates
    Julie Forman-Kay, Hospital for Sick Children
  • Polyubiquitin effects on phase transitions of shuttle protein UBQLN2
    Carlos Castañeda, Syracuse University
  • The role of phase transitions in transcription
    Ibrahim Cissé, California Institute of Technology
Protein machines and disorder
Magazine

Tension between structured complexes and disordered assemblies

This 2022 ASBMB annual meeting session is powered by vinaigrette and other immiscible fluids.

Organelles

Organizers:

  • Jeffrey Brodsky, University of Pittsburgh
  • Elizabeth Vierling, University of Massachusetts, Amherst

Quality control in the early secretory pathway

Session chair: Jeffrey Brodsky, University of Pittsburgh

  • The degradation of misfolded proteins in the ER
    Jeffrey Brodsky, University of Pittsburgh
  • Post-translational control of HMG CoA reductase, the rate-limiting enzyme of cholesterol synthesis
    Russell DeBose–Boyd, University of Texas Southwest Medical Center
  • Signaling principles, signal decoding and integration revealed by stress
    Diego Acosta-Alver, University of California, Santa Barbara
  • The role of rhomboid pseudoproteases in ERADicating misfolded membrane substrates
    Sonya Neal, University of California, San Diego

Organelles and cellular homeostasis

Session chair: Elizabeth Vierling, University of Massachusetts, Amherst

  • Mechanisms of membrane protein sorting
    Sichen (Susan) Shao, Harvard Medical School
  • Peroxisomal quality control in Arabidopsis
    Bonnie Bartel, Rice University
  • Mitochondrial-derived compartments protect cells from nutrient stress
    Adam Hughes, University of Utah
  • Regulation of mitochondrial genome synthesis in animal cells
    Samantha Lewis, University of California, Berkeley

Organizing the cytoplasm during stress

Session chair: Stephanie Moon, University of Michigan

  • Mechanisms of stress granule regulation by ribosome-associated quality control factors
    Stephanie Moon, University of Michigan
  • Control of translation by ubiquitin during oxidative stress
    Gustavo Silva, Duke University
  • Proteins directing lipid fluxes at the ER-lipid droplet continuum
    Elina Ikonen, University of Helsinki
  • The interconnected dynamics of ribonucleoprotein condensates and the endoplasmic reticulum
    Jason Lee, Baylor College of Medicine
Cells beat stress — so can you!
Magazine

Cells beat stress — so can you!

This 2022 ASBMB annual meeting session is powered by stressed-out cells and organelles

RNA/DNA

Organizers:

  • Chuan He, University of Chicago
  • Karolin Luger, University of Colorado, Boulder

Machines on chromatin

Session chair: Karolin Luger, University of Colorado, Boulder

  • Cracking the nucleus: Finding order in chaos
    Clodagh O'Shea, Salk Institute
  • EM structures of nucleosomes with chaperones
    Karolin Luger, University of Colorado Boulder
  • Structural mechanism of human telomerase holoenzyme
    Kelly Nguyen, Medical Research Council Laboratory of Molecular Biology
  • Studying DNA-related processes on DNA curtains
    Ilya Finkelstein, University of Texas at Austin

Noncoding RNA regulation of chromatin states and transcription

Session chair: Chuan He, University of Chicago

  • m6A in the action of regulating the regulators
    Kathy (Fange) Liu, University of Pennsylvania
  • Regulation of noncoding RNA in space and time
    John Rinn, University of Colorado Boulder
  • RNA methylation multitasking on chromatin
    Blerta Xhemalce, University of Texas at Austin
  • RNA methylation in gene expression regulation
    Chuan He, University of Pennsylvania

New approaches to visualize nucleic acids

Session chair: Timothy Stasevich, Colorado State University

  • Visualizing RNA in life cells
    Timothy Stasevich, Colorado State University
  • Visualizing the dynamic genome during development
    Alistair Boettiger, Stanford University
  • 3D in situ RNA sequencing
    Xiao Wang, Broad Institute; Massachusetts Institute of Technology
  • Engineering the repetitive 3D genome in human disease
    Jennifer Phillips–Cremins, University of Pennsylvania
Enzymology
Magazine

What’s new with DNA and RNA?

This 2022 ASBMB annual meeting session is powered by nucleic acids.

Signaling

Organizers:

  • Patrick Eyers, University of Liverpool
  • Anne-Claude Gingras, Lunenfeld–Tanenbaum Research Institute

Atypical signaling mechanisms

Session chair: Patrick Eyers, University of Liverpool

  • Expanding the kinome
    Vincent Tagliabracci, University of Texas Southwestern Medical Center
  • Structural basis for signaling by the HER3 pseudokinase
    Natalia Jura, University of California, San Francisco
  • Tracing copper utilization by kinase signal transduction pathways: Implications for cancer cell processes
    Donita C. Brady, University of Pennsylvania  
  • Non-canonical Ubiquitination
    Satpal Virdee, University of Dundee

New approaches for global cell signaling

Session chair: Anne-Claude Gingras, Lunenfeld–Tanenbaum Research Institute

  • Large scale phosphoproteomics, dynamics and function
    Judit Villén, University of Washington
  • CRISPR sensors for signaling
    Stéphane Angers, University of Toronto
  • Proximity-dependent sensors for signaling
    Anne-Claude Gingras, Lunenfeld–Tanenbaum Research Institute
  • Proteome-scale amino-acid resolution footprinting of protein-binding sites in the intrinsically disordered regions
    Ylva Ivarsson, Uppsala University

Bringing the dead to life: Pseudoenzymes

Session chair: Anne-Claude Gingras, Lunenfeld–Tanenbaum Research Institute

  • Catalytic degradation in pseudoenzymes
    Patrick Eyers, University of Liverpool
  • Cell signaling by protein tyrosine phosphatases
    Hayley Sharpe, Babraham Institute, Cambridge
  • Defining pseudoenzymes in glycosylation pathways
    Natarajan Kannan, University of Georgia
Signalling
Magazine

New kids on the signaling block

This 2022 ASBMB annual meeting session is powered by ligands and receptors.

Tackling adversity: tales of the epigenome

Organizers:

  • Sonia Flores, University of Colorado School of Medicine
  • Vahe Bandarian, University of Utah

Epigenetics and aging: Can we turn back the clock?

Session Chair: tbd

  • A sex-specific role for long noncoding RNA in depression susceptibility and resilience
    Orna Laster, Icahn School of Medicine at Mount Sinai
  • Rethinking the stress paradigm: Exploring new connections between epigenetic adaption and cellular stress
    Kaushik Ragunathan, University of Michigan
  • Live fast, die young: The role of epigenetics in stress and aging
    Anthony Zannas, University of North Carolina
  • Sex-dimorphism in aging: are we missing half of the picture?
    Bérénice Benayoun, University of Southern California

Epigenetic regulation of metabolism: from bench to bedside

Session chair: tbd

  • Intergenerational inheritance of altered metabolism phenotypes after early-life stress in Caenorhabditis elegans
    Sarah Hall, Syracuse University
  • Epigenetic Mediators of Risk for Metabolic Disease
    Mary Elizabeth Patti, Harvard University
  • Consequences of early-life starvation on adult lipid metabolism
    Ryan Baugh, Duke University
  • Extracellular vesicles as stress signals: Identifying novel systemic mechanisms of trauma programming
    Tracey Bale, University of Maryland

Translational epigenetics: The apple doesn’t fall too far from the tree

Session chair: tbd

  • Programmed epigenetic risk: Can stress exposures in utero predispose infants to obesity and metabolic diseases
    Kristen Boyle, Colorado University, Anschutz Medical School
  • The role of maternal factors in epigenetic programming of neurodevelopment
    Patrick McGowan, University of Toronto
  • Epigenetic marks identify asthma susceptibility in African Americans
    Ivanna Yang, Colorado University, Anschutz Medical School
  • Chronic stress, omics, and asthma
    Juan Celedon, Children's Hospital of Pittsburgh
  • Early-life stress and epigenomic regulation of behavior
    Julie-Anne Balouek, Princeton University Education and professional development
Diversity, equity and inclusion
Magazine

Tackling adversity: Tales of the epigenome

This 2022 ASBMB annual meeting session is powered by the need to let everyone know that stress doesn’t define us and that we are resilient in the face of adversity.