Sept. 1, 2015
Phosphoinositides, phosphorylated forms of phosphatidylinositol, or PI, are minor components of the membrane lipids yet play important roles in the signaling of a broad range of cellular processes including cell migration, phagocytosis, cell-cycle regulation and membrane trafficking. Derangements in phosphoinositide signaling are implicated in diseases ranging from congenital malformations and metabolic syndromes to cancers.