Webinars
Quantitative proteomics for understanding epigenetic mechanisms
June 10, 2026 | 12:15–1 p.m. Eastern | Free registration required
Speaker
Benjamin Garcia
Raymond H. Wittcoff Distinguished Professor and Head of the Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine in St. Louis
The Garcia lab has been developing novel proteomic approaches for interrogating protein modifications, especially those involved inepigenetic mechanisms during human disease, publishing over 475 publications. Ben has been recognized with many honors and awards for his research including the American Society for Mass Spectrometry Biemann Medal, the HUPO Discovery in Proteomic Sciences Award, and is a Fellow of the American Chemical Society, the Royal Society of Chemistry and the American Association for the Advancement of Science.
The ASBMB Breakthroughs webinar series offers a window into the cutting-edge biochemistry and molecular biology research driving discovery.
Histones are small proteins that package DNA into chromosomes, and a large number of studies have showed that several post-translational modification sites on histones are associated with gene regulation. Dysregulation of these chromatin networks underlie several human diseases such as cancer. Here I will give an update on advancements that have allowed for high-throughput quantitative mass spectrometry analyses of histone PTMs, and how we are applying these methods to understand epigenetic reprogramming found in some biomedical and biological investigations.
