From signatures to systems: Multi-omics architecture of MASLD

Speaker

Silvia Sookoian
Department Head, CONICET-UMAI

Silvia Sookoian, M.D., Ph.D., is a senior research scientist at CONICET, head of clinical and molecular hepatology, and dean of health sciences at Maimonides University, Argentina. A graduate of the University of Buenos Aires, she is a physician–scientist dedicated to translating scientific discovery into clinical care. Her research focuses on the genetic, epigenetic and molecular mechanisms driving the pathogenesis and progression of metabolic dysfunction-associated steatotic liver disease (MASLD). Sookoian’s work bridges the gap between laboratory innovation and patient-centered outcomes in the field of hepatology.

Register

The ASBMB Breakthroughs webinar series offers a window into the cutting-edge biochemistry and molecular biology research driving discovery.

This webinar explores the shift from identifying isolated molecular markers to understanding the integrated biological networks that drive metabolic dysfunction-associated steatotic liver disease. By synthesizing data across the genomic, transcriptomic, proteomic and lipidomic layers, the session will deconstruct how genetic susceptibility and metabolic flux converge to trigger lipotoxicity and disease progression. It is designed for biochemists, systems biologists, hepatologists, and multi-omics researchers interested in the mechanistic intersections of lipid metabolism, precision phenotyping and the translation of complex datasets into targeted therapeutic interventions.