Structure and function of molecular machines

June 10, 2020 | Duration: 58 mins.

At the beginning of this session, Suzanne Barbour, ASBMB Council member, dean of the graduate school and professor of biochemistry and biophysics at the University of North Carolina at Chapel Hill, gave remarks in reference to the June 10 #ShutDownAcademia, #ShutDownSTEM and #Strike4BlackLives activities. You can watch her remarks here.

Structure–function relationships are at the core of biology. How does the structure of a molecular machine affect its function in one of many diverse biological processes? In this virtual session we delve into the structure–function relationship of machines involved in transcription, G-protein coupled receptors, mitochondrial fission and disordered proteins.

The talks in this virtual event were originally programmed to take place as an in-person Spotlight Session at the 2020 ASBMB Annual Meeting.


Chair: Clement Chan

A module swapping approach to engineer allosterically regulated transcriptional regulators
Clement Chan, University of Texas at Tyler

Modulation of GPCR function by membrane lipids and water
Nipuna Weerasinghe, University of Arizona

Structural studies of human Fis1 reveals a dynamic region important for Drp1 recruitment and mitochondrial fission
Blake Hill, Medical College of Wisconsin