RNA structure and RNA binding proteins
The shape adopted by an RNA plays a key role in how that RNA interacts with proteins. The nature of many of these interactions and how they can lead to changes in RNA stability, sequestration or translation is still being elucidated. In this virtual event, researchers present findings on structure-dependent RNA interactions with proteins and small molecules and their downstream effects in disease.
The talks in this virtual event were originally programmed to take place as an in-person Spotlight Session at the 2020 ASBMB Annual Meeting.
Chair: Jacob Schwartz
Small molecule inhibits enterovirus 71 replication by targeting the IRES domain
Jesse Davila-Calderon, Case Western Reserve University
The phases that separate RNA and transcription
Jacob Schwartz, University of Arizona
Image of 5V16 (Tolbert, M., Morgan, C.E., Pollum, M., Crespo-Hernandez, C.E., Li, M.L., Brewer, G., Tolbert, B.S. (2017) J Mol Biol 429: 2841-2858) created with the PyMOL Molecular Graphics System, Version 2.0 Schrödinger, LLC.