In this virtual session, we dive into the molecular characteristics of alpha synuclein–mediated microglial activation, pathogenic mutations associated with frontotemporal dementia, and how phage counter their host’s defensive response.
The talks in this virtual event were originally programmed to take place as an in-person Spotlight Session at the 2020 ASBMB Annual Meeting.
Chair: Sourvarish Sarkar
Molecular signatures of neuroinflammation induced by α-synuclein aggregates in microglial cells
Souvarish Sarkar, Harvard Medical School
Network analysis of the brain proteome of Grn knockout mice reveals pathogenic mechanisms shared in human frontotemporal dementia caused by GRN mutations
Meixiang Huang, Emory University
Proteomics analysis of a phage-bacterium interaction reveals both hijacking and suppression of host metabolic processes
Ikenna Okekeogbu, Purdue University