Biochemistry of lipids and membranes

July 1, 2020 | Duration: 1 hr. 45 mins.

Cells produce an array of lipids using tightly controlled enzymes to ensure proper physical properties of membranes. This virtual session covers the biochemistry of lipid production in a variety of contexts. Learn, for example, about gut bacteria as they scavenge fatty acids to build new membranes and chloroplasts as they sense and adapt to cold. Other talks cover homeostatic control of lipid-synthesis enzymes and metabolic engineering through systems biology.

The talks in this virtual event were originally programmed to take place as an in-person Spotlight Session at the 2020 ASBMB Annual Meeting.


Chair: Joanna Kwiatek

Membrane phospholipid composition governs Pah1 phosphatidate phosphatase activity
Joanna Kwiatek, Rutgers University

Unique aspects of lipid metabolism in the human gut microbiome
Christopher Radka, St. Jude Children's Research Hospital

Twin enzymes, divergent control: The cholesterogenic enzymes DHCR14 and LBR are differentially regulated transcriptionally and post-translationally
Isabelle Capell-Hattam, UNSW Sydney

How SFR2 is regulated to confer freezing tolerance of the chloroplast envelope membrane
Rebecca Roston, University of Nebraska-Lincoln, Center for Plant Science Innovation

Evidence for a novel interaction between key enzymes in the lipid biosynthesis pathway in S. cerevisiae
Brianna Greenwood, University of Alberta

Elimination of the "essential" Warburg effect in mammalian cells through a multiplex genome engineering strategy
Hooman Hefzi, University of California, San Diego

Unraveling the metabolic and machinery constraints on protein secretion through a novel systems biology framework
Nathan Lewis, University of California, San Diego