• ASBMB 2016 Annual Meeting

Lipids and Lipid Signaling

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Theme Organizers: James Ntambi, Univ. of Wisconsin, Madison and Tobias Walther, Harvard Univ. 

Sunday, April 3, 2016
San Diego Convention Center, Room 6F
4:00 pm - 6:15 pm
Membrane Contact Sites and Lipid Trafficking

Session Chair: Tobias Walther, Harvard Univ.

4:00                         Chair’s Introduction.

4:05   115.1   Broadband   Connections   within   the   Cell:   How Mitochondria Talk to the Endomembrane. B. Kornman. ETH Zurich.

4:30                         An   EE-Golgi   Tether    Facilitates   Ceramide Transfer Out of the ER and Alleviates  Ceramide  Toxicity.  L-K. Liu, A. Toulmay, W. Prinz. NIDDK, NIH. (660.1)

4:45   115.2   Extended-Synaptotagmins   as    Lipid Transporters at ER-PM Contact Sites. K.M. Reinisch, C. Schauder, X. Wu, Y. Saheki, P. Narayanaswamy, F. Torta,M. Wenk, P. De Camilli. Yale Univ. Sch. of Med., Natl. Univ. of Singapore and HHMI, New Haven, CT.

5:10                         Phosphatidylserine  Productionat Membrane ContactsSites Enhances Its Transport Out of the Endoplasmic Reticulum. M. Kannan, S. Lahiri, L-K. Liu, W.A. Prinz.NIDDK, NIH and Univ. of Virginia. (660.2)

5:25                         A  Conserved  Family  of  Proteins  Facilitates Nascent Lipid Droplet Budding from the ER. V. Choudhary, N. Ojha,A. Golden, W.A. Prinz. NIDDK, NIH. (1132.1)

5:40 115.3  ER-Plasma Membrane Contact Sites Regulate Sterol Import in Yeast. A. Menon, Y.Y. Sere, J. Johansen, E. Quon, N. Chauhan, C.T. Beh. Weill Cornell Med. Col. and Simon Fraser Univ., Canada.

6:05                         Discussion. 

Monday, April 4, 2016
San Diego Convention Center, Room 6F
9:45 am - 12:00 pm
Lipid Signaling

Session Chair: George Carman, Rutgers Univ.  

9:45                        Chair’s Introduction.

9:50     243.1         Sphingosine-1-Phosphate:   A   Bridge   from  Bench to Clinic. S. Spiegel. VCU Sch. of Med.     

10:15                      Tracking   Diacylglycerol   Pools   in   Budding Yeast. S. Ganesan, M.L. Sosa Ponce, V. Zaremberg. Univ. of Calgary, Canada. (872.3)

10:30   243.2         Transcriptional Control of Lipid   Homeostasis. P. Totonoz. UCLA.

10:55                       HPV16-E7 Oncoprotein Enhances Ceramide- Mediated Lethal Mitophagy by Regulating the Rb/E2F5/Drp1 Signaling Axis. R. Thomas, N. Oleinik, B. Ogretmen. Med. Univ. of South Carolina. (872.6)

11:10                      Cysteinyl  Leukotriene  2 Receptor Enhances Angiogenesis, Vascular Permeability and Tumor   Metastasis. E. Duah, V. Kondeti, N. Al-Azzam, R. Adapala, P. Patil, C. Thodeti, S. Paruchuri. Univ. of Akron and Northeast Ohio Med. Univ. (872.4)

11:25     (moved from 504.3)  Discovery of a Novel Class of Naturally-Occurring Lipids with Anti-diabetic and Anti-inflammatory Effects. B.   Kahn, M.M. Yore, I. Syed, P.M. Moraes-Vieira, T. Zhang, M.A. Herman, E. Homan, J. Lee, S. Chen, O.D. Peroni, A. Hammarstedt, R. Patel, T.E. McGraw, U. Smith, A. Saghatelian. Beth Israel Deaconess Med. Ctr. and Harvard Med. Sch. 

11:50                      Discussion.

Tuesday, April 5, 2016
San Diego Convention Center, Room 6F
4:00 pm - 6:15 pm
Membrane Lipid Regulation

Session Chair: James Ntambi, Univ. of Wisconsin, Madison

4:00                        Chair’s Introduction.

4:05                        Walter A.  Shaw  Young  Investigator Award in Lipid Research Introduction and Presentation.

4:10                        Functional Lipidomics: From Lipid Timelines to Regulation of Metabolic Networks. C.S. Ejsing. Univ. of So. Denmark. (393.1)

4:35     394.3         Dynamic Regulation of the Signaling Lipid Phosphatidylinositol 3,5-Bisphosphate. L.S. Weisman, N. Jin. Univ. of Michigan.

5:00                         Alterations     in    Acyl    Phosphatidylglycerol Levels in ΔpagP, ΔpldB, and Δcls Escherichia coli Leads to Phenotypic Variance. M. Pourmaleki, T.A. Garrett. Vassar Col., NY. (1133.2)

5:15     394.2         Regulation  of  Lipid  Metabolism  by SREBPs.  P. Espenshade. Johns Hopkins Univ. Sch. of Med.

5:40     394.1         Regulation of Yeast Pah1 Phosphatidate Phosphatase in Lipid Synthesis. G.M. Carman. Rutgers Univ.                    

6:05                         Discussion. 

Wednesday, April 6, 2016
San Diego Convention Center, Room 6F
9:45 am - 12:00 pm
Lipids and Energy Metabolism
Session Chair: Karin M. Reinisch, Yale Univ. Sch of Med
9:45                        Chair’s Introduction.

9:50     504.1         Regulation and Function of  Fatty  Acid  Desaturases.J. Ntambi, M.S. Burhans,C-A. Guo, L.M. Bond. Univ. of Wisconsin-Madison.

10:15                      Multifaceted   Regulation   of  Hepatic  G0/G1 Switch Gene 2 Expression and Relevance to Lipid Metabolism. B. Heckmann, X. Zhang, A. Saarinen, J. Liu. Mayo Clin., Scottsdale. (1134.4)

10:30   504.2         A Potential Mediator of Diabetes-Associated Cardiovascular Disease: The Enzyme FMO3. S. Biddinger. Boston Children’s Hosp.

10:55                      A Novel Mouse Model with Targeted and Inducible Deletion of Intestinal CTP:Phosphocholine Cytidylyltransferase α. J.P. Kennelly, J. van der Veen, R. Nelson, R. da Silva,K. Kelly, K. Leonard,S. Wan, R. Jacobs. Univ. of Alberta. (1134.6)

11:10                      Evidence of a Perilipin-5 Splice Variant. B.L. Ranzau, D.M. DuBreuil, T. Hubbell, J.T. Tansey. Otterbein Univ. (1134.7)

11:25   (moved from 243.3) The Phase of Fat: Mechanisms and Physiology of Lipid Synthesis and Storage. R.V. Farese, T. Walther. Harvard Univ., Boston.

11:50                      Discussion.