• ASBMB 2016 Annual Meeting

Chemical Biology

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Theme Organizers: Erin Carlson, Univ. of Minnesota and Joseph Jez, Washington Univ. in St. Louis 
The most up-to-date program information, view abstracts and plan your itinerary, download the EB2016 app or view online here: http://app.core-apps.com/eb2016

Sunday, April 3, 2016
San Diego Convention Center, Room 6C
9:45 am - 12:00 pm
Welcome to the Post-Antibiotic Era 

Session Chair: Jennifer Prescher, Univ. of California, Irvine 

9:45                  Chair’s Introduction.

9:50    100.1    Chemical   Probes   for   Histidine   Kinase   Profiling and Inhibitor Discovery. E. Carlson. Univ. of Minnesota, Minneapolis.

10:15                 Acetylating    Polymyxin    Antibiotics:    Clues toward Substrate Specificity of PA3944 Gcn5-Related N-Acetyltransferase of Unknown Function. M.L. Kuhn, L. Joe, B. Amsler, B. Zhang, K. Majorek, R. Yen, W. Wu, G. Gassner, T. Baird, W. Minor. San Francisco State Univ. and Univ. of Virginia. (615.1)

10:30    100.2   The Ying and Yang of Antibiotic Discovery and Resistance. G. Wright. McMaster Univ., Canada.

10:55                 Menaquinone  Biosynthesis:  An  Antibacterial Target? J. Matarlo. Stony Brook Univ. (612.2)

11:10                 Elucidating  the  Molecular  Basis   of  Protein and Polymer Display in Pathogenic Bacteria for Novel Anti- virulence Drug Development. M. Kattke, M. Sawaya, D. Cascio, A. Duong, M. Elliot, R. Clubb. UCLA and McMaster Univ., Canada. (613.3)

11:25    100.3    New  Antibiotics  for  the  Post-antibiotic   Era. S. Mobashery. Univ. of Notre Dame.

11:50                  Discussion.

Monday, April 4, 2016
San Diego Convention Center, Room 6C
4:00 pm - 6:15 pm
The Greening of Chemical Biology

Session Chair: Michael Burkhart, Univ. of California, San Diego 

4:00                         Chair’s Introduction.

4:05      253.1        Chemical  Biology   and   Endomembrane Trafficking in Plants.G.R. Hicks, C. Zhang,W. Van de Ven, R. Li, N. Raikhel. Univ. of California, Riverside.

4:30                         Molecular Cloningand Expression of a Putative Oleate Hydratase Isozyme from Nocardia cholesterolicum NRRL 5767. J-K. Huang, H.B. Alhmadi, D.R. Vanderway, C.A. Hoerner, L. Wen. Western IllinoisUniv. (838.1)

4:45       253.2        Alkaloid Biosynthesis in Plants. S.  O’Connor. John Innes Ctr., Norwich, U.K.

5:10                         Digging  into  Rice  Diterpenoid  Biosynthesis. R. Peters. Iowa State Univ. (1146.1)

5:25                         Structural   Basis   of   Distinct  Salicylic  Acid Glucosylation in Arabidopsis Thaliana by Two Homologous Enzymes: Implications forPlant Stress Response. A.M. George Thompson, C.V. Iancu, J. Dean, J-y. Choe. Rosalind Franklin Univ. and DePaul Univ. (1142.3)

5:40       253.3        Molecular Controlsin Plant HormoneSignaling.J. Jez. Washington Univ. in St. Louis.

 6:05                        Discussion.  


Tuesday, April 5, 2016
San Diego Convention Center, Room 6C
9:45 am - 12:00 pm
Chemical Communication, Biological Regulation

Session Chair: Erin Carlson, Univ. of Minnesota 

9:45                    Chair’s Introduction.

9:50     380.1     Imaging    Cell-Cell    Interactions    with Bioluminescent Probes. J. Prescher. Univ. of California, Irvine.

10:15                  Design and Development of Chemically Gated Artificial Regulatory Domains. D.T. Cunningham-Bryant. Univ. of Washington. (809.1)

10:30   380.2     Understanding the Regulation of   Ferroptosis. S. Dixon. Stanford Univ.

10:55                  Engineered       Caspases       with       Altered Specificities Enable Identification of Exosites. J.A. Hardy, M. Hill, D.J. MacPherson, P. Wu, O. Julien, J.A. Wells. Univ. of Massachusetts Amherst and UCSF. (842.10)

11:10                  Determination  of HNO-Derived Modifications on the Cardiac Protein Phospholamban. G. Keceli, A. Majumdar, C.N. Thorpe, J.E. Mahaney, N. Paolocci, J.P. Toscano. Johns Hopkins Univ., Edward Via Col. of Osteo. Med., VA and Johns Hopkins Med. Inst. (1092.7)

11:25     380.4   Metabolic    Control    via    Protein-Protein    Interaction. M. Burkart. UCSD.

11:50                  Discussion.

Wednesday, April 6, 2016
San Diego Convention Center, Room 6C
2:15 pm - 4:30 pm
Chemistry, Biology, and Sustainability
Session Chair: Joseph Jez, Washington Univ. in St. Louis 

2:15                  Chair’s Introduction.

2:20    508.1   The Future of Biobased Chemicals. B. Shanks. Iowa State Univ.

2:45                  A  Novel  Thermotolerant β-Glucosidase from Aspergillus nidulans Has Activity across a Broad pH Profile and a Likely Bacterial Origin. R. Auta, I. Radecka, P. Hooley. Univ. of Wolverhampton, U.K. and Kaduna State Univ., Nigeria. (1070.1)

3:00     508.2   Engineering Microbial Fatty Acid Biosynthesis as an Industrial Biotechnology Platform. A. Schirmer. REG Life Sci., South San Francisco.

3:25                  Optimization and Lipid Quantitation of Potential Algal Biofuels Feedstocks. S.J. Brad, B.E. Umbach, E.D. Gehlhausen, C.R. Sweet. U.S. Naval Acad., Annapolis. (838.5) 3:40    Comparison of Stability and Kinetic Properties of DszB from N. asteroides A3H1 and R. erythropolis   IGTS8. A.    Hutchinson-Lundy, A. Crithary, J.M. Schmitz, L. Watkins. James Madison Univ. (1087.2)

3:55    508.3    Expanding   the   Boundaries   of Biocatalysis. H. Zhao. Univ. of Illinois at Urbana-Champaign.

4:20                  Discussion.