Register by Feb. 7 and save! Register

The 2022 ASBMB Annual Meeting, held in conjunction with Experimental Biology, will take place in person April 2–5 in Philadelphia.

Join thousands of scientists from multiple disciplines with shared research interests. Present your latest findings, hear inspiring lectures, participate in workshops, and form new bonds that will help you achieve the most important work of your career.

Experience four days of immersive and insightful exchange among life scientists from around the world.

View the program schedule

Program planning committee co-chairs

Vahe Bandarian
Vahe Bandarian
University of Utah
Martha Cyert
Martha Cyert
Stanford University

See full list of organizers >

About EB

The Experimental Biology conference — hosted by five scientific societies supporting studies in biochemistry and molecular biology, anatomy, pharmacology, physiology and pathology — attracts thousands of researchers and exhibitors.

Starting in 2023, the five societies will be parting ways. So don’t miss this last chance to converse and forge collaborations with scientists from multiple disciplines with shared research interests.

COVID-19 vaccine requirement

For the health and safety of our members and community, EB 2022 is requiring COVID-19 vaccines for anyone attending the event.

Learn more

Important dates

Registration

Register for the 2022 ASBMB Annual Meeting

Feb. 7 Early registration ends
Feb. 8 Advance registration begins
March 18 Advance registration ends
March 19 Regular registration begins

Abstracts

See list of ASBMB abstract topics

Jan. 27 Last-chance abstract submission deadline

What you need to know

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Abstracts

Submit a last-chance abstract to an ASBMB topic category for a chance to present a poster during the 2022 ASBMB Annual Meeting.

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Program schedule

Deepen your knowledge of significant research trends during daily sessions curated by pioneers and innovators.

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Award lectures

These high-profile speakers will cover impactful research and education and diversity initiatives.

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Workshops

Leading experts offer practical advice for adopting the latest tools, software, methodologies and best practices to propel your work from bench to publication.

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Undergraduate Poster Competition

The Undergraduate Poster Competition returns in person on Saturday, April 2.

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Interest groups

Share new findings and best practices and engage in activities and discussions that forge lasting and fruitful connections.

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Housing information

Reserve your room at the official EB hotel.

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Annual meeting travel awards

The ASBMB offers more than $270,000 in awards to assist first authors presenting research at the annual meeting.

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Exhibits and sponsorships

Information for exhibitors and sponsors.

Sign up for updates

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Registration

Register

Registration includes access to scientific sessions, poster sessions, exhibits, Career Central and more.

Students and trainees will be required to present credentials during registration. See requirements

Not a member? Join the ASBMB and save!

Registration type Early registration
(on/before Feb. 7)
Advance registration
(Feb. 8 – March 18)
Regular registration
(after March 18)
Members Nonmembers Members Nonmembers Members Nonmembers
Regular $430 $630 $570 $770 $595 $795
Postdoctoral trainee $335 $435 $435 $535 $460 $560
Graduate student $95 $135 $105 $145 $130 $170
Undergraduate student $25 $40 $35 $50 $50 $60
Retired $150 $185 $170 $205 $195 $230
1-day pass $285 $385 $295 $385 $310 $410

Eligibility requirements

Graduate students

You must have a department head or research advisor certify your student eligibility. If registering online, enter the name and email address of your department head. Postdoctoral fellows, hospital residents, interns and laboratory technicians do not qualify as students.

Undergraduate students

You must certify your student eligibility. If registering online, enter the name and email address of your department head.

Postdoctoral trainee

Trainees have obtained their doctoral degree within the last five years and are currently enrolled in a postdoctoral trainee program.

Program schedule

All sessions and events will take place at the Pennsylvania Convention Center unless otherwise noted.

Saturday April 2
Sunday April 3
Monday April 4
Tuesday April 5

Saturday agenda

9:00 AM - 11:00 AM

Research Education Interest Group — Connecting the community for the benefit of student outcomes

Organizers: Ellis Bell, University of San Diego, and Regina Stevens–Truss, Kalamazoo College

This session will present recent research on the impact of collaboration between students and institutions in course-based undergraduate research experiences. Attendees will have the opportunity to join a team of like-minded faculty to network and develop action items for future discussion and research. Attendees will be able to connect with colleagues.

Future challenges in education research
Daniel Dries, Juniata College
Bringing student research experiences to everyone
Betsy Martinez–Vas, Hamline College
Pedagogical research: It's not just for DBERs anymore
Jessica Bell, University of San Diego
Fostering student collaborations through CUREs
Kevin Callahan, St. John Fisher College
10:30 AM - 4:00 PM

Undergraduate Student Poster Competition

Open to selected candidates only.

  • 10:30 – 11:00 a.m.
    Orientation
  • 11:00 a.m. – 12:00 p.m.
    Check-in and poster setup
  • 11:00 a.m. – 12:00 p.m.
    Judges' orientation
  • 12:00 – 3:30 p.m.
    Undergraduate Student Poster Competition
  • 3:30 – 4:00 p.m.
    Poster removal
12:45 PM - 2:45 PM

Lipids Interest Group — Novel insight into roles of lipids in signaling and human disease

Organizers: Michael Airola, Stony Brook University, and John Burke, University of Victoria

This session will inform participants about the most cutting-edge lipid research being performed. Most of the speakers will be postdocs and graduate students. The session will cover a wide range of biochemical, biophysical and cellular approaches to study lipid signaling, in line with the organizers' approach for their successful ASBMB Lipid Research Division Seminar Series. By keeping a broad range of topics, we hope to provide novel collaborative opportunities.

Palmitoylation targets the calcineurin phosphatase to the phosphatidylinositol 4-kinase complex at the plasma membrane
Idil Ulengin–Talkish, Stanford University
Membrane phosphoinositides stabilize GPCR–arrestin complexes and offer temporal control of complex assembly and dynamics
John Janetzko, Stanford University
Ice2 promotes ER membrane biogenesis in yeast by inhibiting the conserved lipin phosphatase complex
Dimitris Papagiannidis, Heidelberg University
Imaging cytoplasmic lipid droplets in vivo with fluorescent perilipin 2 and perilipin 3 knock-in zebrafish
Meredith Wilson, Carnegie Institution for Science
12:45 PM - 2:45 PM

Chemical Biology Interest Group — Emerging chemical approaches to complex biology

Organizers: Minkui Luo, Memorial Sloan Kettering Cancer Center, and Jianmin Gao, Boston College

Chemical biology can be broadly defined as a research field relying on chemical tools to interrogate biology for discovery and perturbation. The ASBMB has the historical mission to advance the research of biochemistry and molecular biology through diverse approaches and platforms. Such a mission establishes a key common ground between the ASBMB and the chemical biology community given complementary strength and interest. The Chemical Biology Interest Group aims to better promote crosstalk between the two fields. Importantly, we will primarily dedicate speaking opportunities to emerging young investigators as well as people from historically marginalized groups. The talks will showcase the emerging technologies that chemical biologists are developing to tackle complex biological problems. Chemical biologists will benefit from the perspectives and questions raised by experts in biology. Biologists will mutually benefit by considering broad utilities of the chemical biology tools and methods.

Chemical biology applied to hematologic disorders
Laura Dassama, Stanford University
Protein-targeting cyclic peptides as chemical biology tools
Min Xue, University of California, Riverside
Interrogating novel acetylation substrates with probes based on fluorine-thiol displacement reaction
Rongsheng (Ross) Wang, Temple University
All roads lead to...? A journey along an untested route to inhibitor discovery and characterization in mycobacterium tuberculosis
Jessica Seeliger, Stony Brook University
12:45 PM - 2:45 PM

Signaling Interest Group — New paradigms in hormonal regulation of cancer and development

Organizers: Marina Holz, New York Medical College, and Mythreye Karthikeyan, University of Alabama, Birmingham

This session will cover the role of hormones in cancer and parallel developmental programs with emphasis on new insights, paradigms and mechanisms, and future directions. Attendees will learn about new areas of investigation and consideration of emerging paradigms in hormonal signaling.

Hormonal control of sex differences in neural gene expression
Jessica Tollkuhn, Cold Spring Harbor Laboratory
Novel insights into GnRH receptor signaling and the central control of fertility
Daniel Bernard, McGill University
Spatial metabolic regulation and endocrine resistance in metastatic breast tumors
Zeynep Madak–Erdogan, University of Illinois Urbana–Champaign
TLE3 ensures luminal epithelial cell fate in breast cancer by acting as a co-repressor for FOXA1
Ruth Keri, Case Western Reserve University
12:45 PM - 2:45 PM

Glycobiology Interest Group — Glycobiology at the cutting edge

Organizers: Nadine Samara, National Institute of Dental and Craniofacial Research, and Stacy Malaker, Yale University

The session will feature speakers from academia, industry, startups and funding agencies who perform high-risk/high-reward glycobiology research that will take the field forward. Attendees will learn about the future of glycobiology and appreciate its importance in biomedical research. Early-career glycoscientists will learn about the possible paths they can pursue.

12:45 PM - 2:45 PM

Protein Interest Group — Membrane proteins

Organizers: Matthias Buck, Case Western University, and Fran Barrera, University of Tennessee

The goal of this interest group session is to build a community of researchers in the field of membrane proteins. The study of membrane proteins is living a golden era, as strides are being made toward understanding how these key proteins function. This event will highlight recent advances in a broad range of membrane proteins that are central players in key cellular processes.

Delivery of recombinant SARS-CoV-2 envelope protein into the membranes of living human cells from amphipol solutions
Charles R. Sanders, Vanderbilt University
Bacterial outer membrane models: Learning from atomistic simulations
Thereza Soares, University of São Paulo
Candidalysin uses a unique mechanism to form membrane pores
Francisco Barrera, University of Tennessee, Knoxville
Activation mechanism of the EGF receptor
John Kuriyan, University of California, Berkeley
12:45 PM - 2:45 PM

Neuroscience Interest Group

Organizers: Jason Yi and Harrison Gabel, Washington University School of Medicine in St. Louis

This session will feature recent work in the field examining pathways and molecules that cause neurological dysfunction, with a particular emphasis on genetic neurodevelopmental disorders.

Function genetic dissection of disease-linked variants in UBE3A
Jason Yi, Washington University School of Medicine in St. Louis
Dissecting neuron-specific epigenetic mechanisms in neurodevelopmental disorders
Harrison Gabel, Washington University School of Medicine in St. Louis
The role of chromatin in neuronal function and neurodevelopmental disorders
Erica Korb, University of Pennsylvania
Optical interrogation of dopaminergic phenotypes in neurofibromatosis type 1
J. Elliott Robinson, Cincinnati Children’s Hospital
3:00 PM - 5:00 PM

Enzymology Interest Group

Organizers: Juan Mendoza, University of Chicago, and Kayunta Johnson, University of Texas at Arlington

The interest group session will be have talks by new and mid-career investigators and networking opportunities. The research to be presented will be focused on the structure–function of enzymes essential to cellular function and cellular regulation and relevant to human health and disease. Techniques and cutting-edge research include X-ray crystallography, cryo-EM, NMR, enzyme kinetics, enzymology and protein engineering. Attendees will be exposed to a diverse panel of researchers performing cutting-edge science. Participants will gain insights into how some scientists use combined structure and engineering approaches to elucidate key enzymatic processes of cells. New investigators will leave with insight related to their careers and respective fields through a Q&A session related to research, diversity, inclusion and promotion.

3:00 PM - 5:00 PM

Protein Interest Group — Post-translational modification: emerging topics and techniques

Organizers: Lauren Ball, Medical University of South Carolina, and Fangliang Zhang, University of Miami

The goal of this session is to provide a forum enabling interaction of scientists interested in the elucidating the impact of regulatory post-translational modifications on physiology, disease and drug response. Attendees will learn about discoveries relating to the role of PTMs in diseased or normal physiologies and have the opportunity to start new collaborative research.

Protein arginylation in animal cells
Anna Kashina, University of Pennsylvania
Detection of single protein molecules with quantum effects
Lan Yang, Washington University in St. Louis
Identifying regulators of protein O-GlcNAcylation
Natasha Zachara, Johns Hopkins School of Medicine
Protein posttranslational modifications at the virus–host interface
Ileana Cristea, Princeton University
3:00 PM - 5:00 PM

Mitochondria Interest Group

Organizers: Laura Lackner, Northwestern University, and Oleh Khalimonchuk, University of Nebraska–Lincoln

The session seeks to promote cross-talk across the areas of basic mitochondrial biology and molecular mechanisms of disease and aging, and provide an opportunity for biomedical researchers to explore and discover potentially unrecognized mechanisms of disease. Holding an interest group session that focuses on the diverse aspects of mitochondria and pathways that underlie the pathophysiologic mechanisms of age-associated diseases will provide a forum to uniquely gather the international community of scientists in mitochondria, cell metabolism and aging research. The overarching goal is to organize an exciting and interactive interest group session, expand the array of participants and trigger new synergy among researchers in the mitochondria and age-associated disease fields. We also aim to provide an excellent training experience for young scientists and foster professional connections between junior and more established investigators.

Uncovering novel circuits of electron flow in the mammalian electron transport chain
Jessica Spinelli, Whitehead Institute for Biomedical Research
Structure-based insights into control of heme biosynthesis
Breann Brown, Vanderbilt University
Phosphorylation-based regulation of mitochondrial metabolism
Natalie Niemi, Washington University in St. Louis
Expanding the set of genetically encoded tools for compartment-specific manipulation of redox metabolism in living cells
Valentin Cracan, Scintillion Institute; Scripps Research
3:00 PM - 5:00 PM

Signaling Interest Group — Emerging mechanisms of cellular communication in physiology and disease

Organizers: Michelle Mendoza, University of Utah Huntsman Cancer Institute, and Robert Zoncu, University of California, Berkeley

This session will cover new mechanisms in intra- and intercellular communication that have been uncovered through quantitative and structural biology. Attendees will get a broad overview of new signaling questions and approaches.

The tumor mechanical microenvironment instructs metastatic behavior of breast cancer cells
Ghassan Mouneimne, University of Arizona
Regulation of GPCR signaling at the Golgi
Roshanak Irannejad, University of California, San Francisco
High resolution insights into receptor tyrosine kinase signaling across the membrane
Natalia Jura, University of California, San Francisco
Unconventional GPCR-PKA signaling in the hedgehog pathway
Benjamin Myers, University of Utah
4:30 PM - 5:30 PM

Undergraduate student workshop: Speed networking

6:00 PM - 7:00 PM

Tang Lecture

7:00 PM - 8:30 PM

EB opening reception

Sunday agenda

7:00 AM - 8:00 AM

ASBMB member and first-time attendee orientation

8:00 AM - 8:45 AM

ASBMB welcome and business meeting

8:45 AM - 9:15 AM

Herbert Tabor Research Award lecture

My journey with cAMP-dependent protein kinase
Susan Taylor, University of California, San Diego
9:30 AM - 11:30 AM

Enzyme structure and function

Riboflavin catabolism: the destruction of an icon
Tadhg Begley, Texas A&M University
Repairing enzymes using spare parts
Catherine Drennan, Massachusetts Institute of Technology Chair
Machinery in motion: New insights into mitochondrial proteostasis
Gabriel Lander, Scripps Research Institute
An aerobic strategy for C-H bond functionalization
Jennifer Bridwell–Rabb, University of Michigan
9:30 AM - 11:30 AM

Structure/function and manipulation and imaging of the glycocalyx

Nanoscale physical biology of the cellular glycocalyx
Matthew J. Paszek, Cornell University
MALDI imaging mass spectrometry mapping of the glycocalyx
Richard R. Drake, Medical University of South Carolina
Genetic and small molecule strategies to edit the glycocalyx
Siriram Neelamegham, State University of New York at Buffalo
Enzymatic removal of cell surface antigens as a route towards universal O type blood and organs
Stephen Withers, University of British Columbia Chair
9:30 AM - 11:30 AM

Macromolecular complexes

In situ structural analysis of the nuclear pore complex
Martin Beck, Max Planck Institute of Biophysics Chair
Molecular-scale structure of a high-curvature membrane
Adam Frost, University of California, San Francisco
Structure and function of DNA transposition assemblies
Orsolya Barabas, University of Geneva
9:30 AM - 11:30 AM

Machines on chromatin

Cracking the nucleus: Finding order in chaos
Clodagh O'Shea, Salk Institute
EM structures of nucleosomes with chaperones
Karolin Luger, University of Colorado Boulder Chair
Structural mechanism of human telomerase holoenzyme
Kelly Nguyen, Medical Research Council Laboratory of Molecular Biology
Studying DNA-related processes on DNA curtains
Ilya Finkelstein, University of Texas at Austin
9:30 AM - 11:30 AM

Epigenetics and aging: can we turn back the clock?

A sex-specific role for long noncoding RNA in depression susceptibility and resilience
Orna Laster, Icahn School of Medicine at Mount Sinai
Rethinking the stress paradigm: Exploring new connections between epigenetic adaption and cellular stress
Kaushik Ragunathan, University of Michigan Medical School
Extracellular vesicles as stress signals: Identifying novel systemic mechanisms of trauma programming
Tracy Bale, University of Maryland School of Medicine
Sex-dimorphism in aging: are we missing half of the picture?
Bérénice Benayoun, University of Southern California
9:30 AM - 11:30 AM

Quality control in the early secretory pathway

The degradation of misfolded proteins in the ER
Jeffrey Brodsky, University of Pittsburgh Chair
Post-Translational control of HMG CoA reductase, the rate-limiting enzyme of cholesterol synthesis
Russell DeBose–Boyd, University of Texas Southwest Medical Center
Signaling principles, signal decoding and integration revealed by stress
Diego Acosta–Alver, University of California, Santa Barbara
The role of rhomboid pseudoproteases in ERADicating misfolded membrane substrates
Sonya Neal, University of California, San Diego
9:30 AM - 11:30 AM

Inclusive and civil communication

Chair: Erin Sayer, University of Nebraska–Lincoln

Seeing equity in courses from data to faculty learning communities
Chad Brassil, University of Nebraska–Lincoln
Creative strategies to perform an inclusive faculty search
Anita Corbett, Emory University
Creative approaches to perform an inclusive faculty search
Wendy Gilbert, Yale University
9:30 AM - 11:30 AM

Atypical signaling mechanisms

Chair: Patrick Eyers, University of Liverpool

Expanding the kinome
Vincent Tagliabracci, University of Texas Southwestern Medical Center
Structural basis for signaling by the HER3 pseudokinase
Natalia Jura, University of California, San Francisco
Tracing copper utilization by kinase signal transduction pathways: Implications for cancer cell processes
Donita C. Brady, University of Pennsylvania
Non-canonical Ubiquitination
Satpal Virdee, University of Dundee
9:30 AM - 11:30 AM

Metabolism and model systems

Identifying toxic metabolites and their roles in disease
Dohoom Kim, University of Massachusetts Medical School
Transcriptional regulation of primary and specialized metabolism
Siobhan Brady, University of California, Davis
Interorgan crosstalk and metabolism regulation in Drosophila
Norbert Perrimon, Harvard University
9:30 AM - 11:30 AM

Organizing signaling domains through non-vesicular lipid transfer and membrane contacts

Chair: Orna Cohen-Fix, National Institute of Diabetes and Digestive and Kidney Diseases

Regulation of PIP2 homeostasis at ER-plasma membrane contacts by Nir proteins
Jen Liou, University of Texas Southwestern Medical Center
Roles for inter-organelle contacts in organizing metabolism
W. Mike Henne, University of Texas Southwestern Medical Center, Dept. of Cell Biology
Systematic analysis of membrane contact sites
Maya Schuldiner, Weizmann Institute of Science
Novel pathways of intracellular membrane lipid transport and neurodegenerative diseases
Pietro De Camilli, Yale University School of Medicine/Howard Hughes Medical Institute
11:45 AM - 12:15 PM

Meet the experts

12:15 PM - 1:45 PM

Advocacy Town Hall

Sponsored by the ASBMB Public Affairs Advisory Committee

Join the ASBMB Public Affairs Advisory Committee to hear about the intersection of policy and science. What policies has the Biden administration enacted to support the nation’s biomedical research enterprise? And how can federal agencies support researchers still struggling with the impacts of COVID-19 and related university and laboratory shutdowns. ASBMB Public Affairs Director Sarina Neote will be joined by the PAAC chair, Rick Page, who will field your questions on politics, science policy and getting involved in advocacy.

12:30 PM - 1:00 PM

Meet the experts

12:45 PM - 2:00 PM

Poster sessions

1:00 PM - 2:00 PM

Accreditation program Q&A session

2:15 PM - 2:45 PM

ASBMB–Merck Award lecture

The phase of fat: mechanisms and physiology of lipid storage
Robert V. Farese & Tobias Walther, Harvard University
2:45 PM - 3:15 PM

William C. Rose Award lecture

Progress toward understanding protein control of reaction outcome in the diverse reactivity of iron (II) — and 2-oxoglutarate-dependent oxygenases
J. Martin Bollinger, Pennsylvania State University
3:30 PM - 4:30 PM

Spotlight Sessions

Oral presentations selected from volunteer abstracts.

3:30 PM - 4:50 PM

JBC Herbert Tabor Early Career Investigator Awards

Chair: George DeMartino, University of Texas Southwestern Medical Center

The evolution and mechanism of GPCR proton sensing
Jacob Rowe, University of Miami Miller School of Medicine
Structures and kinetics of Thermotoga maritima MetY reveal new insights into the predominant sulfurylation enzyme of bacterial methionine biosynthesis
Jodi Brewster, University of Wollongong
SARS-CoV-2 infects cells after viral entry via clathrin-mediated endocytosis
Armin Bayati, McGill University
Molnupiravir promotes SARS-CoV-2 mutagenesis via the RNA template
Calvin Gordon, University of Alberta
3:30 PM - 4:30 PM

Walter A. Shaw Young Investigator Award in Lipid Research lecture and spotlight session

Snapshots of lipid synthesis and fat storage
Michael Airola, Stony Brook University
3:30 PM - 5:00 PM

ASBMB Award for Exemplary Contributions to Education lecture and session

It's all about the students
Joseph Provost, University of San Diego
4:45 PM - 5:45 PM

Spotlight Sessions

Oral presentations selected from volunteer abstracts.

6:00 PM - 7:30 PM

Control of inflammation by dietary interventions

Organizer: Michael N. Sack, National Heart, Lung and Blood Institute

This workshop will explore how different dietary components and/or temporal dietary intake strategies play a role in modulating inflammation and disease pathophysiology. Explore how specific nutrients via diverse regulatory mechanisms — transcription, GPCR signaling, post-translational modification and metabolic signaling — alter immune cell responsiveness.

Attendees will learn about integration of environmental cues with intracellular regulatory pathways to drive immune cell responsiveness.

Target audience: Scientists focusing on cardiometabolic risk, nutrient signaling, inflammation and effects of dietary interventions on health.

6:00 PM - 7:30 PM

Approaches to teaching in the biosciences using different course modalities

Organizer: Monica Rieth, Southern Illinois University, Edwardsville

Become familiar with new modes of instruction. Learn to work outside of your teaching comfort zone by incorporating new exercises and lessons that align with other teaching modalities.

The workshop will include ways to incorporate new teaching modalities into biochemistry education both in the classroom and in the lab using examples and evidence-based practices reported in the current literature. Exercises and sample lessons will be implemented to help attendees adapt new techniques to their current and future practices.

For example, a lesson on amino acids and protein structure may be taught in a lecture-style format and attendees would be asked to adapt this lesson to a flipped-style classroom or problem-based learning exercise. How would each person change the format/content using examples to illustrate these changes?

Attendees will also be asked to identify and/or anticipate any advantages or disadvantages to changing to a new teaching modality, such as increased/decreased student engagement. Open discussions will further introduce attendees to teaching practices as of yet unreported in the literature.

Attendees will develop a network of peers who can provide support to them.

Target audience: Instructors teaching undergraduate- or graduate-level biochemistry courses or labs both for majors and nonmajors. Those interested in exploring different teaching styles and modalities in their courses.

6:00 PM - 7:30 PM

Increasing diversity through master's degree programs

Organizer: Bob Rose, North Carolina State University

Network with other faculty members contributing to programs for research-based master's degrees.

We developed a research-based master's program in biochemistry from an NSF S-STEM training grant to fund low-income students and increase diversity of associated departments. Our funding is ending, and we are looking for ideas for continued funding of the program and developing support in a Ph.D.-focused department.

Target audience: Graduate faculty involved with STEM education.

6:00 PM - 7:30 PM

The power of storytelling

Storytelling is an essential component of communication. It can be used to connect with a diverse audience and make challenging subjects more accessible. Mastering storytelling requires creative flexibility, dexterity with language and willingness to get personal. Learn how to incorporate yourself as a scientist into your science story in a way that strengthens your message without sacrificing scientific integrity. This interactive session will lead participants through hands-on storytelling training that is based on one of the modules from the ASBMB course The Art of Science Communication.

6:00 PM - 7:30 PM

Success in scientific publishing workshop

Will my data stand the test of time?

Is my writing clear, compelling and engaging?

Will I be able to reach an audience that will give my research its greatest impact? 

These are questions authors ask themselves when preparing manuscripts for publication. 

The American Society for Biochemistry and Molecular Biology is home to the Journal of Biological Chemistry, the Journal of Lipid Research, and Molecular & Cellular Proteomics. In this 90-minute workshop, members of the society’s publications staff will offer insights into the publication pipeline and provide you with tips on three essential topics: presenting data, writing well and sharing your work.

Presenting:

  • Ken Farabaugh, Developmental Editor
  • Stephanie Paxson, Journal Marketing Associate
6:00 PM - 7:30 PM

Women scientists networking event — The evolution of work–life integration in the time of COVID-19

Integrating work and personal life is challenging and has been made even more so for women during the COVID-19 pandemic. The ASBMB Women in Biochemistry and Molecular Biology Committee is hosting its annual networking dinner and a panel discussion titled “The evolution of work–life Integration in the time of COVID-19.” Lea Vacca Michel of the Rochester Institute of Technology, winner of the society’s Early-Career Leadership Award, and Marlene Belfort of the University at Albany, winner of the Mid-Career Leadership Award, will be panelists. 

They will be joined by members at various career levels to discuss their experiences with integrating work and their personal lives during the pandemic. Attendees are encouraged to weigh in during the discussion.

6:00 PM - 7:00 PM

ASBMB Student Chapters event

7:00 PM - 9:00 PM

ASBMB welcome reception

Sponsored by the ASBMB Minority Affairs Committee
7:00 PM - 9:00 PM

ASBMB Student Chapters reception

Monday agenda

8:00 AM - 8:30 AM

DeLano Award for Computational Biosciences lecture

Hyperbolic geometry in biological systems
Tatyana Sharpee, Salk Institute for Biological Studies
8:30 AM - 9:00 AM

Avanti Award in Lipids lecture

PI 3-Kinase signaling: A journey in three AKTs
Alex Toker, Beth Israel Deaconess Medical Center
9:15 AM - 11:15 AM

Frontiers in enzymology

Chair: Tadhg Begley, Texas A&M University

Structural biology of natural product biosynthetic enzymes
Janet Smith, University of Michigan
Correlated motions in enzymes
Nozomi Ando, Cornell University
Nickel pincer nucleotide: biosynthesis and function
Robert Hausinger, Michigan State University
Bacterial biosynthesis of natural products
Katherine Ryan, University of British Columbia
9:15 AM - 11:15 AM

Glycans in cell biology

Hypersialylation of tumor cells promotes pancreatic cancer progression
Susan Bellis, University of Alabama at Birmingham Chair
Receptor N-glycosylation links metabolism with signaling
James Dennis, Lunenfeld–Tanenbaum Research Institute
Modeling the mucinous glycocalyx to unravel receptor pattern recognition by influenza A viruses
Kamil Godula, University of California, San Diego
Cell surface glycan engineering reveals that matriglycan alone can recapitulate dystroglycan binding and function
Geert-Jan Boons, University of Georgia
9:15 AM - 11:15 AM

Phase transitions of structured complexes and cellular machinery

Building the microtubule cytoskeleton via phase transitions
Sabine Petry, Princeton University
Understanding how oncogenic fusion proteins drive aberrant gene expression through phase separation
Richard Kriwacki, St. Jude Children’s Research Hospital
Decoding plasticity of the dark proteome
Edward Lemke, Johannes Gutenberg University; Institute of Molecular Biology Chair
9:15 AM - 11:15 AM

Noncoding RNA regulation of chromatin states and transcription

m6A in the action of regulating the regulators
Kathy (Fange) Liu, University of Pennsylvania
Jeannie Lee, Massachusetts General Hospital
RNA methylation multitasking on chromatin
Blerta Xhemalce, University of Texas at Austin
RNA methylation in gene expression regulation
Chuan He, University of Pennsylvania Chair
9:15 AM - 11:15 AM

Epigenetic regulation of metabolism: from bench to bedside

Intergenerational inheritance of altered metabolism phenotypes after early-life stress in Caenorhabditis elegans
Sarah Hall, Syracuse University
Epigenetic mediators of risk for metabolic disease
Mary Elizabeth Patti, Harvard Medical School
Early-life stress and epigenomic regulation of behavior
Julie-Anne Balouek, Princeton University
Live fast, die young: The role of epigenetics in stress and aging
Anthony Zannas, University of North Carolina
9:15 AM - 11:15 AM

Organelles and cellular homeostasis

Chair: Elizabeth Vierling, University of Massachusetts, Amherst

Mechanisms of membrane protein sorting
Sichen (Susan) Shao, Harvard Medical School
Peroxisomal quality control in Arabidopsis
Bonnie Bartel, Rice University
Mitochondrial-derived compartments protect cells from nutrient stress
Adam Hughes, University of Utah
Regulation of mitochondrial genome synthesis in animal cells
Samantha Lewis, University of California, Berkeley
9:15 AM - 11:15 AM

Strategies for assessment in higher education

Peer collaboration and review: A guide to iterative improvement in learning
Dan Bernstein, University of Kansas
What makes a competitive applicant? Assessing students for graduate/professional school applications
Erin Sayer, University of Nebraska–Lincoln
Developing BMB assessment questions for use in the undergraduate classroom
Victoria Moore, Elon University Chair
9:15 AM - 11:15 AM

New approaches for global cell signalling

Chair: Vincent Tagliabracci, University of Texas Southwestern Medical Center

Large scale phosphoproteomics, dynamics and function
Judit Villén, University of Washington
CRISPR sensors for signaling
Stéphane Angers, University of Toronto
Proximity-dependent sensors for signaling
Anne-Claude Gingras, Lunenfeld–Tanenbaum Research Institute
Proteome-scale amino acid resolution footprinting of protein-binding sites in the intrinsically disordered regions
Ylva Ivarsson, Uppsala University
9:15 AM - 11:15 AM

Complex metabolic interactions

Metabolic adaptation to oxidative stress at the host–microbe interface
Stavroula Hatzios, Yale University Chair
Deconvoluting host–gut microbiota co-metabolism
Pamela Chang, Cornell University
The tiny pharmacists within: how the human gut microbiome impacts drug metabolism and disposition
Peter Turnbaugh, University of California, San Francisco
Metabolic outliers in human disease
Ralph D. DeBarardinis, University of Texas Southwestern Medical Center
9:15 AM - 11:15 AM

Novel approaches to understand membrane composition and structure

Chair: Lois Weisman, University of Michigan

Chemical tools for understanding phospholipase D signaling
Jeremy Baskin, Cornell University
Control of the cellular lipid landscape by inositol lipids
Tamas Balla, National Institutes of Health
Volume electron microscopy analysis reveals a new type of membrane junction required for mixing of parental genomes after fertilization
Orna Cohen-Fix, National Institute of Diabetes and Digestive and Kidney Diseases
Automatic whole cell organelle segmentation in volumetric electron microscopy
Aubrey Weigel, Howard Hughes Medical Institute Janelia Research Campus
11:30 AM - 12:00 PM

Meet the experts

12:00 PM - 2:00 PM

ASBMB career programming at EB Career Central

Bite-size sessions focused on developing key skills to support your career progression and exploring different career paths available to those with scientific training.

The art of the interview: Ask great questions, give great answers and enjoy the process

No matter where you are in your career, having great interview skills can help you make the next step. When it comes down to brass tacks, an interview is just a conversation. Laurel Oldach, a scientist-turned-science-writer at the ASBMB, will talk about both sides of interviewing: how you can make the most of informational interviews that you conduct and how you can feel more relaxed and prepared when you’re the interviewee.

Exploring careers in science publishing

Ever wonder what it is like to work behind the scenes to bring research to publication? Join members of the ASBMB publications staff to explore the variety of positions in publishing that benefit from scientific training. Speakers will share insights into the different roles, the day-to-day and how to make the leap from research to publishing.

Managing your mentoring relationships through mentoring up

Once you have found a mentor, what comes next in making the most of this relationship? Richard McGee of Northwestern University Feinberg School of Medicine will focus on the essential and critical elements of effective mentoring relationships, with an emphasis on mentoring up — how students and postdocs can use these principles to guide and help their mentors provide what they are seeking from them.

Science policy skills — helpful for scipol and beyond

Whether you are interested in science policy as a possible career or enjoy advocacy to support your science, there is a subset of skills necessary to make you an attractive job candidate or skilled advocate. But did you know that those same skills can help you be a better scientist too? Join ASBMB Public Affairs Director Sarina Neote and members of the society’s Public Affairs Advisory Committee to learn about how to improve those soft skills — and apply them no matter where your career takes you.

12:15 PM - 12:45 PM

Meet the experts

12:30 PM - 1:45 PM

Poster sessions

2:00 PM - 2:30 PM

Earl and Thressa Stadtman Young Scholar Award lecture

Telomerase holoenzymes
Kathleen Collins, University of California, Berkeley
2:30 PM - 3:00 PM

Mildred Cohn Award in Biological Chemistry lecture

Flavivirus NS1: Structure and function of an enigmatic virulence factor
Janet Smith, University of Michigan
3:15 PM - 4:15 PM

Spotlight Sessions

Oral presentations selected from volunteer abstracts.

3:15 PM - 4:30 PM

Exciting biological insights revealed by proteomics: A Molecular & Cellular Proteomics presentation

Chair: Pierre Thibault, Institute for Research in Immunology and Cancer

Michal Bassani–Sternberg, Ludwig Institute for Cancer Research
Susan Klaeger, Broad Institute
Victor Engelhard, University of Virginia School of Medicine
3:15 PM - 5:15 PM

The Alice and C.C. Wang Award in Molecular Parasitology symposium

How one eukaryote invades and co-opts the cells of another: The story of the truly audacious toxoplasma gondii
John Boothroyd, Stanford University
4:30 PM - 5:30 PM

Spotlight Sessions

Oral presentations selected from volunteer abstracts.

5:45 PM - 7:15 PM

RNA export at the nuclear pore complex

Organizer: Mary Dasso, Eunice Kennedy Shriver National Institute of Child Health and Human Development

RNA export is a complicated and critical stage of gene expression, which remains poorly understood. It involves components of both the RNA processing and nuclear trafficking machinery. This workshop seeks to bring together different emerging approaches and model systems that are being applied to untangle the sequence and logic of RNA processing and export events.

The focus of this workshop will be on nuclear pore proteins as guardians of mRNA export and their role in the selectivity of RNA export in health and disease. The workshop will bring together laboratories using cryo-EM, X-ray crystallography, biochemistry, nuclear microinjection, genetics, cell biology, CRISPR/Cas9-AID gene editing, live imaging, viral and animal models to elucidate interactions between nucleoporins, mRNA and RNA-accessory proteins at the nuclear pore complex.

Attendees will learn about cutting-edge tools and techniques and their application to the process of mRNA export. They will learn up-to-date progress, explore unresolved questions in the field and meet world-class experts.

Target audience: This workshop will appeal to a diverse group of scientists (students, postdoctoral researchers and group leaders) who are interested in RNA processing and export, the regulation of gene expression, nuclear trafficking and nucleoporins.

5:45 PM - 7:15 PM

Pedagogical lessons learned during the time of COVID-19

Organizer: Phillip Ortiz, State University of New York

This workshop will include a presentation of and discussions about pedagogical approaches used during the shift to teaching at a distance during the COVID-induced closing of some campuses. As we often learn more from failure than success, this workshop will include approaches that worked and that didn't.

Attendees will hear about creative and innovative approaches to teaching and learning. In addition, as it has been noted by people who were successful at shifting some or all of their teaching to different modalities that some content is better taught by those modalities (which leaves time in their courses to expand the content that requires face-to-face instruction), the workshop may lead to productive conversations about educational innovation.

Target audience: Primarily BMB educators, but also all educators at the undergraduate and graduate levels, including new and established faculty members at all types of colleges and universities, teaching assistants and postdoctoral researchers who are interested in careers at primarily undergraduate institutions. Undergraduate and graduate students also are welcome attend so that they may share their insights and experiences during the Q&A and open discussion portions of the session.

5:45 PM - 7:15 PM

Becoming the boss of your career

Organizer: Erica Gobrogge, Van Andel Institute

Establishing career goals, navigating challenging conversations associated with those goals, and working outside the laboratory to advance your career can be challenging for scientists at all career stages. In addition, these conversations can be particularly difficult for international scientists, whose cultural norms may be different than those commonly found in the U.S.

Participants will develop their own goals, draft plans for achieving them and practice navigating conversations they might encounter while advocating for those goals. The mission of this workshop is to encourage, support and empower scientists to take charge of their careers.

Target audience: This workshop primarily will be of interest to undergraduate students, graduate students and postdoctoral researchers, but scientists at career stages are welcome.

5:45 PM - 7:15 PM

Transforming scientific research into equitable outreach

How do you transform your passion for science into equitable outreach? This interactive session will cover the importance of science outreach and its impacts on enhancing diversity, equity and inclusion within the biomedical science research workforce. Chelsey Spriggs, co-founder of Black in Microbiology (#BlackInMicro) and a member of the first cohort of the ASBMB MOSAIC program, will share her journey as a role model for underrepresented students interested in biological research. She will describe how she has engaged in outreach and mentorship and how, through her work as a board member of the Black in Microbiologists Association, she aims to enhance the visibility of Black scientists in the field. Be ready to have a thoughtful discussion with your peers and brainstorm ways to use science outreach as a vehicle to equity and inclusion.

Tuesday agenda

8:00 AM - 8:30 AM

Ruth Kirschstein Diversity in Science Award lecture

Beyond diversity: Building a culture of inclusion in science
Tracy Johnson, University of California, Los Angeles
8:30 AM - 9:00 AM

Bert and Natalie Vallee Award in Biomedical Science lecture

Tissue stem cells: survival of the fittest
Elaine Fuchs, Rockefeller University
9:15 AM - 11:15 AM

Radical SAM enzymology

Chair: Tadhg Begley, Texas A&M University

Radical SAMs and the vast unexplored chemistry of RiPP natural products
Douglas Mitchell, University of Illinois Urbana-Champaign
The biosynthesis of lipoic acid: A saga of death, destruction and rebirth
Squire Booker, Pennsylvania State University
Unraveling the secrets of radical SAM mechanisms
Joan Broderick, Montana State University
How do aerobic organisms solve the oxygen sensitivity problem of [4Fe-4S] in radical SAM enzymes?
Hening Lin, Cornell University; Howard Hughes Medical Institute
9:15 AM - 11:15 AM

Physiological impact of glycans in tissue homeostasis and disease – focus on cell-ECM interactions

The glycocalyx in tumor progression and metastasis
Valerie Weaver, University of California, San Francisco Chair
The heparaase/syndecan-1 axis in cancer progression
Ralph D. Sanderson, University of Alabama at Birmingham
Reprogramming T cells to target glycans and overcome glycan-mediated immunosuppression for cancer therapy
Avery Posey, University of Pennsylvania
Orchestrated intragranular restructuring of mucins during secretory granule maturation
Kelly G. Ten Hagen, National Institute of Dental and Craniofacial Research
9:15 AM - 11:15 AM

Physiological and pathological phase transitions of disordered proteins

Phase behavior of intrinsically disordered prion-like domains
Tanja Mittag, St. Jude Children’s Research Hospital Chair
Regulation of translation and deadenylation via biomolecular condensates
Julie Forman–Kay, Hospital for Sick Children
Polyubiquitin effects on phase transitions of shuttle protein UBQLN2
Carlos Castañeda, Syracuse University
The role of phase transitions in transcription
Ibrahim Cissé, California Institute of Technology
9:15 AM - 11:15 AM

New approaches to visualize nucleic acids

Visualizing RNA in life cells
Timothy Stasevich, Colorado State University Chair
Visualizing the dynamic genome during development
Allistair Bottiger, Stanford University
3D in situ RNA sequencing
Xiao Wang, Broad Institute; Massachusetts Institute of Technology
Engineering the repetitive 3D genome in human disease
Jennifer Phillips–Cremins, University of Pennsylvania
9:15 AM - 11:45 AM

Translational epigenetics: The apple doesn’t fall too far from the tree

Programmed epigenetic risk: Can stress exposures in utero predispose infants to obesity and metabolic diseases?
Kristen Boyle, University of Colorado Anschutz Medical Campus
The role of maternal factors in epigenetic programming of neurodevelopment
Patrick McGowan, University of Toronto
Epigenetic marks identify asthma susceptibility in African Americans
Ivanna Yang, University of Colorado Anschutz Medical Campus
Chronic stress, omics and asthma
Juan Celedon, Children's Hospital of Pittsburgh
9:15 AM - 11:15 AM

Organizing the cytoplasm during stress

Mechanisms of stress granule regulation by ribosome-associated quality control factors
Stephanie Moon, University of Michigan Chair
Control of translation by ubiquitin during oxidative stress
Gustavo Silva, Duke University
Proteins directing lipid fluxes at the ER-lipid droplet continuum
Elina Ikonen, University of Helsinki
The interconnected dynamics of ribonucleoprotein condensates and the endoplasmic reticulum
Jason Lee, Baylor College of Medicine
9:15 AM - 11:15 AM

Bringing the dead to life: pseudoenzymes

Chair: Anne-Claude Gingras, Lunenfeld–Tanenbaum Research Institute

Catalytic degradation in pseudoenzymes
Patrick Eyers, University of Liverpool
Cell signaling by protein tyrosine phosphatases
Hayley Sharpe, Babraham Institute
Defining pseudoenzymes in glycosylation pathways
Natarajan Kannan, University of Georgia
9:15 AM - 11:15 AM

Metabolic mechanisms

Lipid metabolism and ferroptosis
Scott Dixon, Stanford University Chair
Too much and never enough: Synthetic excess and metabolic inefficiency of aneuploidy in tumorigenesis
Emma Watson, Harvard Medical School
Uncovering conditional vulnerabilities in cancer
Jason Cantor, University of Wisconsin
The genetics of tumor suppression by p53
Maureen Murphy, Wistar Institute
9:15 AM - 11:15 AM

Membrane dynamics in trafficking and signaling

Chair: Tamas Balla, National Institutes of Health

Regulation of membrane dynamics via phosphoinositide signaling cascades
Lois Weisman, University of Michigan
Novel mechanisms in phosphoinositide turnover
Raghu Padinjat, National Centre for Biological Sciences
Regulation of COPII dynamics in development and disease
Anjon Audhya, University of Wisconsin–Madison
Intracellular trafficking during neutrophil chemotaxis
Carole Parent, University of Michigan
11:30 AM - 12:00 PM

Meet the experts

12:15 PM - 12:45 PM

Meet the experts

12:30 PM - 1:45 PM

Poster sessions

2:00 PM - 2:30 PM

ASBMB Young Investigator Award lecture

Chromatin-based modulations underlying gene regulation and pathogenesis
Greg G. Wang, University of North Carolina
2:45 PM - 3:45 PM

Thermodynamics in the everyday life of biologists

Organizer: Assen Marintchev, Boston University School of Medicine

This workshop will introduce the concepts of thermodynamic coupling and binding kinetics in the context of biochemical experiments, with emphasis on practical applications and common mistakes.

Learn how to properly plan, perform and analyze binding experiments and avoid everyday errors:

  • How to use thermodynamic coupling to indirectly calculate a binding KD from the KD's of coupled interactions, if direct determination is impossible or difficult.
  • How to compare binding constants to determine whether they are mutually consistent.
  • How to determine whether and when two or more molecules bind to each other in vivo.
  • How to quantitatively evaluate experimental binding constants: what they mean for the underlying biological process and whether they are physically possible.

Target audience: Ph.D. students, postdocs and faculty members.

2:45 PM - 3:45 PM

Lipid diversity and disease: Spotlight on Journal of Lipid Research Junior Associate Editors

Chair: George Carman, Rutgers University

The role of Dennd5b in intestinal lipid absorption
Scott Gordon, University of Kentucky
Judi Simcox, University of Wisconsin–Madison
Lessons and surprises from mice with humanized bile acid composition
Rebecca A. Haeusler, Columbia University Medical Center
2:45 PM - 3:45 PM

Spotlight Sessions

Oral presentations selected from volunteer abstracts.

2:45 PM - 4:15 PM

Race and mental health in STEM

STEM graduate students and postdoctoral fellows, particularly those of color, often experience microaggressions, discrimination and harassment in the workplace, which can lead to adverse mental health outcomes. We must support these scientists by encouraging dialogue and taking action. In this session, sponsored by the ASBMB’s Maximizing Opportunities for Scientific and Academic Independent Careers program, or MOSAIC, panelists Cirleen DeBlaere of Georgia State University, Carlota Ocampo of Trinity Washington University and Stephen Quaye of Ohio State University will lead insightful discussions pertaining to the intersectionality of race and mental health of STEM trainees.

4:00 PM - 5:00 PM

Spotlight Sessions

Oral presentations selected from volunteer abstracts.