2022 ASBMB Annual Meeting

Interest groups

A unique feature of the ASBMB annual meeting is its interest group networking events. During these gatherings, researchers and practitioners with aligned affinities share new findings and best practices and engage in activities and discussions that forge lasting and fruitful connections.

Sessions on the following topics will take place on Saturday, April 2, 2022.

Organizers, speakers, panelists and participants must register for the ASBMB Annual Meeting/Experimental Biology 2022 to access these events.

April 2, 2022, 12:45 p.m. – 2:45 p.m.

Chemical Biology Interest Group — Emerging chemical approaches to complex biology

Organizers: Minkui Luo, Memorial Sloan Kettering Cancer Center, and Jianmin Gao, Boston College

Chemical biology can be broadly defined as a research field relying on chemical tools to interrogate biology for discovery and perturbation. The ASBMB has the historical mission to advance the research of biochemistry and molecular biology through diverse approaches and platforms. Such a mission establishes a key common ground between the ASBMB and the chemical biology community given complementary strength and interest. The Chemical Biology Interest Group aims to better promote crosstalk between the two fields. Importantly, we will primarily dedicate speaking opportunities to emerging young investigators as well as people from historically marginalized groups. The talks will showcase the emerging technologies that chemical biologists are developing to tackle complex biological problems. Chemical biologists will benefit from the perspectives and questions raised by experts in biology. Biologists will mutually benefit by considering broad utilities of the chemical biology tools and methods.

Join the Chemical Biology Interest Group Slack channel

Chemical biology applied to hematologic disorders
Laura Dassama, Stanford University
Protein-targeting cyclic peptides as chemical biology tools
Min Xue, University of California, Riverside
Interrogating novel acetylation substrates with probes based on fluorine-thiol displacement reaction
Rongsheng (Ross) Wang, Temple University
Activity-based probes for an ancient family of RNA modifying enzymes
Ralph Kleiner, Princeton University
April 2, 2022, 3 p.m. – 5 p.m.

Enzymology Interest Group

Organizers: Juan Mendoza, University of Chicago, and Kayunta Johnson, University of Texas at Arlington

The interest group session will be have talks by new and mid-career investigators and networking opportunities. The research to be presented will be focused on the structure–function of enzymes essential to cellular function and cellular regulation and relevant to human health and disease. Techniques and cutting-edge research include X-ray crystallography, cryo-EM, NMR, enzyme kinetics, enzymology and protein engineering. Attendees will be exposed to a diverse panel of researchers performing cutting-edge science. Participants will gain insights into how some scientists use combined structure and engineering approaches to elucidate key enzymatic processes of cells. New investigators will leave with insight related to their careers and respective fields through a Q&A session related to research, diversity, inclusion and promotion.

Join the Enzymology Interest Group Slack channel

Illuminating the natural biochemistry of lanthanides and leveraging it for biomining, bioseparations, biosensing, and health applications
Joseph Cotruvo, Jr., Pennsylvania State University
An affinity-matured DLL4 ligand for broad-spectrum activation and inhibition of Notch signaling
Vince Luca, Moffitt Cancer Center
Molecular mechanisms of biased signaling at the angiotensin receptor
Laura Wingler, Duke University
Allosteric regulation of metabolic enzymes ACLY and G6PD
Ronen Marmorstein, University of Pennsylvania
April 2, 2022, 12:45 p.m. – 2:45 p.m.

Glycobiology Interest Group — Glycobiology at the cutting edge

Organizers: Nadine Samara, National Institute of Dental and Craniofacial Research, and Stacy Malaker, Yale University

The session will feature speakers from academia, industry, startups and funding agencies who perform high-risk/high-reward glycobiology research that will take the field forward. Attendees will learn about the future of glycobiology and appreciate its importance in biomedical research. Early-career glycoscientists will learn about the possible paths they can pursue.

Join the Glycobiology Interest Group Slack channel

Adventures with bacterial peptidoglycans
Catherine Grimes, University of Delaware
Inspiring glycoscience innovation: A story of chembind glycoscience
Yunpeng Liu, Chembind LLC
New protein tools for generation and enrichment of O-linked glycopeptides
Christopher Taron, New England Biolabs
Mucins, glycans and coronavirus transmission
Jessica Kramer, University of Utah
April 2, 2022, 12:45 p.m. – 2:45 p.m.

Lipids Interest Group — Novel insight into roles of lipids in signaling and human disease

Organizers: Michael Airola, Stony Brook University, and John Burke, University of Victoria

This session will inform participants about the most cutting-edge lipid research being performed. Most of the speakers will be postdocs and graduate students. The session will cover a wide range of biochemical, biophysical and cellular approaches to study lipid signaling, in line with the organizers' approach for their successful ASBMB Lipid Research Division Seminar Series. By keeping a broad range of topics, we hope to provide novel collaborative opportunities.

Join the Lipids Interest Group Slack channel

Palmitoylation targets the calcineurin phosphatase to the phosphatidylinositol 4-kinase complex at the plasma membrane
Idil Ulengin–Talkish, Stanford University
Membrane phosphoinositides stabilize GPCR–arrestin complexes and offer temporal control of complex assembly and dynamics
John Janetzko, Stanford University
Ice2 promotes ER membrane biogenesis in yeast by inhibiting the conserved lipin phosphatase complex
Dimitris Papagiannidis, Heidelberg University
Imaging cytoplasmic lipid droplets in vivo with fluorescent perilipin 2 and perilipin 3 knock-in zebrafish
Meredith Wilson, Carnegie Institution for Science
April 2, 2022, 3 p.m. – 5 p.m.

Mitochondria Interest Group — Multifaceted mitochondria

Organizers: Laura Lackner, Northwestern University, and Oleh Khalimonchuk, University of Nebraska–Lincoln

The session seeks to promote cross-talk across the areas of basic mitochondrial biology and molecular mechanisms of disease and aging, and provide an opportunity for biomedical researchers to explore and discover potentially unrecognized mechanisms of disease. Holding an interest group session that focuses on the diverse aspects of mitochondria and pathways that underlie the pathophysiologic mechanisms of age-associated diseases will provide a forum to uniquely gather the international community of scientists in mitochondria, cell metabolism and aging research. The overarching goal is to organize an exciting and interactive interest group session, expand the array of participants and trigger new synergy among researchers in the mitochondria and age-associated disease fields. We also aim to provide an excellent training experience for young scientists and foster professional connections between junior and more established investigators.

Join the Mitochondria Interest Group Slack channel

Uncovering novel circuits of electron flow in the mammalian electron transport chain
Jessica Spinelli, Whitehead Institute for Biomedical Research
Structure-based insights into control of heme biosynthesis
Breann Brown, Vanderbilt University
Phosphorylation-based regulation of mitochondrial metabolism
Natalie Niemi, Washington University in St. Louis
Expanding the set of genetically encoded tools for compartment-specific manipulation of redox metabolism in living cells
Valentin Cracan, Scintillion Institute; Scripps Research
April 2, 2022, 12:45 p.m. – 2:45 p.m.

Neuroscience Interest Group

Organizers: Jason Yi and Harrison Gabel, Washington University School of Medicine in St. Louis

This session will feature recent work in the field examining pathways and molecules that cause neurological dysfunction, with a particular emphasis on genetic neurodevelopmental disorders.

Join the Neuroscience Interest Group Slack channel

Function genetic dissection of disease-linked variants in UBE3A
Jason Yi, Washington University School of Medicine in St. Louis
Dissecting neuron-specific epigenetic mechanisms in neurodevelopmental disorders
Harrison Gabel, Washington University School of Medicine in St. Louis
The role of chromatin in neuronal function and neurodevelopmental disorders
Erica Korb, University of Pennsylvania
Optical interrogation of dopaminergic phenotypes in neurofibromatosis type 1
J. Elliott Robinson, Cincinnati Children’s Hospital
April 2, 2022, 12:45 p.m. – 2:45 p.m.

Protein Interest Group — Membrane proteins

Organizers: Matthias Buck, Case Western University, and Fran Barrera, University of Tennessee

The goal of this interest group session is to build a community of researchers in the field of membrane proteins. The study of membrane proteins is living a golden era, as strides are being made toward understanding how these key proteins function. This event will highlight recent advances in a broad range of membrane proteins that are central players in key cellular processes.

Join the Membrane Proteins Interest Group Slack channel

Delivery of recombinant SARS-CoV-2 envelope protein into the membranes of living human cells from amphipol solutions
Charles R. Sanders, Vanderbilt University
TRPV channels gating by endogenous and exogenous modulators
Vera Moiseenkova, University of Pennsylvania
Candidalysin uses a unique mechanism to form membrane pores
Francisco Barrera, University of Tennessee, Knoxville
Activation mechanism of the EGF receptor
John Kuriyan, University of California, Berkeley
April 2, 2022, 3 p.m. – 5 p.m.

Protein Interest Group — Post-translational modification: emerging topics and techniques

Organizers: Lauren Ball, Medical University of South Carolina, and Fangliang Zhang, University of Miami

The goal of this session is to provide a forum enabling interaction of scientists interested in the elucidating the impact of regulatory post-translational modifications on physiology, disease and drug response. Attendees will learn about discoveries relating to the role of PTMs in diseased or normal physiologies and have the opportunity to start new collaborative research.

Join the Post-translational Modification Interest Group Slack channel

Protein arginylation in animal cells
Anna Kashina, University of Pennsylvania
Detection of single protein molecules with quantum effects
Lan Yang, Washington University in St. Louis
Identifying regulators of protein O-GlcNAcylation
Natasha Zachara, Johns Hopkins School of Medicine
Protein posttranslational modifications at the virus–host interface
Ileana Cristea, Princeton University
April 2, 2022, 9 a.m. – 11 a.m.

Research Education Interest Group — Connecting the community for the benefit of student outcomes

Organizers: Ellis Bell, University of San Diego, and Regina Stevens–Truss, Kalamazoo College

This session will present recent research on the impact of collaboration between students and institutions in course-based undergraduate research experiences. Attendees will have the opportunity to join a team of like-minded faculty to network and develop action items for future discussion and research. Attendees will be able to connect with colleagues.

Join the Research Education Interest Group Slack channel

Future challenges in education research
Daniel Dries, Juniata College
Bringing student research experiences to everyone
Betsy Martinez–Vas, Hamline College
Pedagogical research: It's not just for DBERs anymore
Jessica Bell, University of San Diego
Fostering student collaborations through CUREs
Kevin Callahan, St. John Fisher College
April 2, 2022, 3 p.m. – 5 p.m.

Signaling Interest Group — Emerging mechanisms of cellular communication in physiology and disease

Organizers: Michelle Mendoza, University of Utah Huntsman Cancer Institute, and Robert Zoncu, University of California, Berkeley

This session will cover new mechanisms in intra- and intercellular communication that have been uncovered through quantitative and structural biology. Attendees will get a broad overview of new signaling questions and approaches.

Join the cellular communication Signaling Interest Group Slack channel

The tumor mechanical microenvironment instructs metastatic behavior of breast cancer cells
Ghassan Mouneimne, University of Arizona
Regulation of GPCR signaling at the Golgi
Roshanak Irannejad, University of California, San Francisco
High resolution insights into receptor tyrosine kinase signaling across the membrane
Natalia Jura, University of California, San Francisco
Unconventional GPCR-PKA signaling in the hedgehog pathway
Benjamin Myers, University of Utah
April 2, 2022, 12:45 p.m. – 2:45 p.m.

Signaling Interest Group — New paradigms in hormonal regulation of cancer and development

Organizers: Marina Holz, New York Medical College, and Mythreye Karthikeyan, University of Alabama, Birmingham

This session will cover the role of hormones in cancer and parallel developmental programs with emphasis on new insights, paradigms and mechanisms, and future directions. Attendees will learn about new areas of investigation and consideration of emerging paradigms in hormonal signaling.

Join the hormonal regulation Signaling Interest Group Slack channel

Hormonal control of sex differences in neural gene expression
Jessica Tollkuhn, Cold Spring Harbor Laboratory
Novel insights into GnRH receptor signaling and the central control of fertility
Daniel Bernard, McGill University
Spatial metabolic regulation and endocrine resistance in metastatic breast tumors
Zeynep Madak–Erdogan, University of Illinois Urbana–Champaign
TLE3 ensures luminal epithelial cell fate in breast cancer by acting as a co-repressor for FOXA1
Ruth Keri, Case Western Reserve University