In the cover story of the March 2014 issue, contributor Diedre Ribbens explores the causes of seasonal affective disorder, or the “winter blues.” Also, we offer two Q&As by science writer Rajendrani Mukhopadhyay: one with John Denu, a new associate editor at the Journal of Biological Chemistry, and one with Jonathan Weissman, the plenary lecturer for the ASBMB annual meeting next month in San Diego. In his “President’s Message,” Jeremy Berg analyzes the effects of the across-the-board federal budget cuts on investigators seeking R-series grants from the National Institutes of Health. And, on a related note, ASBMB’s public affairs director, Benjamin Corb, writes about why it’s so hard to secure increased research-funding appropriations even when politicians throughout the political spectrum agree on science’s value to the nation and humanity. Finally, we begin our coverage of the ASBMB annual award winners. We will feature the remaining winners next month.