On our cover, we feature biochemist Peggy A. Whitson, who will head out again next year to the International Space Station, where she will conduct experiments for many Earth-bound scientists. This issue contains two installments in our Defying Stereotypes series about people with scientific training who have careers away from the bench: One story is about sportswriter Jay Jaffe, and the other is about bestselling romance novelist Stephanie Laurens. This issue includes tips for undergraduates embarking upon their first research experiences and words of wisdom for new Ph.D. recipients. In the President's Message, Steve McKnight takes a look at the scoring criteria for National Institutes of Health grants and proposes a new approach to NIH grant review. For Lipid News enthusiasts, Symeon Siniossoglou discusses the "many faces of lipins." Finally, don't miss this issue's three contributions to the "Generations" series. We hope you enjoy the May issue!