Large DNA virus produces rare sugars


In a recent Journal of Biological Chemistry paper, researchers reported finding that a nucleocytoplasmic large DNA virus from the Mimiviridae family encodes genes that allow it to produce a rare type of sugar. Nucleocytoplasmic large DNA viruses have large genomes, and some are known to carry genes that encode glycosylation systems, including genes for enzymes and substrates required for the production of complex carbohydrates.

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Unraveling the ligand-protein interaction between cocaine and the dopamine transporter


Rejwi Acharya Dahal of the University of North Dakota School of Medicine and Health Sciences and collaborators used computational and biochemical approaches to identify the site of cocaine binding to DAT.

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Taking aspirin plus fish oil? Consider this


A study in the Journal of Lipid Research recently focused on using natural compounds to combat inflammation. Researchers at the University of Western Australia showed that fish oil supplementation in healthy adults increased factors that help mitigate inflammation. What’s more, their results also indicated that aspirin may not have any additional benefits when it is taken with fish oil.

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A new epigenetic target for treating all cancers


What doesn’t kill you makes you stronger. This slogan for personal resilience is unfortunately the motto by which cancer cells exist. Reduced oxygen, which usually prompts cells to die, makes tumor cells harder to destroy and more resistant to cancer treatments. However, investigators at the Nanyang Technological University in Singapore recently reported in the journal Molecular & Cellular Proteomics a promising drug target that could stop the tumor before it builds its strength

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