The structure and applications of isolated alpha helices


A recent minireview in the Journal of Biological Chemistry focuses on the isolated, stable single α-helical, or SAH, domains of proteins.

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The importance of iron in birch allergies


Seasonal allergies affect millions of people every year, causing itching, sneezing and runny noses. While many of the molecules responsible for provoking allergic reactions have been identified, the way these molecules sensitize our immune systems and cause allergic reactions has remained mysterious. However, a research group with members from the Technical University of Madrid and the Medical University of Vienna has begun to shed some light on this mystery.

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Metabolic clearance of cholesterol


In a recent minireview in the Journal of Biological Chemistry, Michael Phillips at the Perelman School of Medicine at the University of Pennsylvania discusses the molecular mechanisms of cellular cholesterol efflux. He explains this basic mechanism of cholesterol turnover in the body and covers the latest developments in the field.

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Stop the fat


A research team at the University of Utah recently discovered a protein in zebrafish that apparently determines how long the intestine stores dietary lipids before they are delivered to tissues and the bloodstream. This delay, it seems, ultimately reduces blood cholesterol and triglyceride levels. The team’s findings were reported in the Journal of Lipid Research.

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