Award

Sabatini honored for ‘providing critical insights into the linkages between energy, nutrient metabol

He won ASBMB's Earl and Thressa Stadtman Award
Geoff Hunt
March 27, 2012

The American Society for Biochemistry and Molecular Biology has named David Sabatini, associate professor of biology at the Massachusetts Institute of Technology and a Howard Hughes Medical Institute investigator, the winner of the society’s inaugural Earl and Thressa Stadtman Scholar Award

awards_sabatiniDavid Sabatini

About the award

The Earl and Thressa Stadtman Scholar Award was established by their friends and colleagues to preserve their legacies as scientists and mentors. It is awarded to a scientist with 10 or fewer years of post-postdoctoral experience, including medical residency and fellowship. The award is given every other year, alternating with the Earl and Thressa Stadtman Distinguished Scientist Award. The award consists of a plaque, a $10,000 cash award and travel expenses for the ASBMB annual meeting to present a lecture.

Sabatini received the award for his work identifying the mTOR pathway, a major regulator of mammalian cell growth and a central component of pathways relating to metabolism and aging. Susan Lindquist, a professor at MIT, praised Sabatini’s work on mTOR for “providing critical insights into the linkages between energy, nutrient metabolism and cancer.”

The work done by Sabatini’s lab has led to the development of several drugs aimed at treating cancer. His lab also recently has demonstrated the ability of diet to affect aging and cell growth.

Solomon Snyder from Johns Hopkins University was not bashful in his praise for his former graduate student. “Virtually all of the major breakthroughs relating to signaling pathways whereby growth factors and nutrient amino acids regulate protein translation can be attributed to one individual: David Sabatini,” Snyder said.

Upon completing his M.D./Ph.D. at Johns Hopkins, Sabatini was invited to become a fellow at the prestigious Whitehead Institute in 1997. He was elevated to full member in 2002. Sabatini also began a professorship in the department of biology at MIT in 2005.

In addition to his experimental insights, Sabatini has earned praise for his technological inventions, including the reverse transfection microarray, a rapid, high-scale throughput technique in which cells expressing defi ned cDNAs are screened for select phenotypes, thereby enabling investigation into the effects of varying gene expression levels on a cellular rather than population level. This technology also allows for simultaneous screening of the efficacy of multiple small-molecule compounds that serve as potential drug candidates.

“I am delighted to receive this honor from my colleagues and am humbled to receive an award named for pioneering biochemists whose work has influenced all of us who pretend to be one,” said Sabatini.

Geoff Hunt

Geoff Hunt is the ASBMB's former outreach manager. 

Join the ASBMB Today mailing list

Sign up to get updates on articles, interviews and events.

Latest in People

People highlights or most popular articles

Agarwal elected; Bassler honored; remembering Jane Park
Member News

Agarwal elected; Bassler honored; remembering Jane Park

January 27, 2020

Awards, promotions and more. Find out what's going on in the lives of ASBMB members.

Premed from day 1 — researcher from day 3
Student Chapters

Premed from day 1 —
researcher from day 3

January 27, 2020

In his senior year, Koushik Muralidharan was elected ASBMB Student Chapter president at Monmouth University.

Understanding how arsenic changes chromatin and causes cancer
Research Spotlight

Understanding how arsenic changes chromatin and causes cancer

January 23, 2020

Yvonne Fondufe–Mittendorf, who took a winding path from the Republic of Cameroon to the bluegrass of Kentucky, calls herself “an academic tourist.”

Kensal E. van Holde (1928 – 2019)
Retrospective

Kensal E. van Holde (1928 – 2019)

January 22, 2020

One of the world’s premier physical biochemists and a longtime associate editor of the Journal of Biological Chemistry is remembered by his friend and colleague Christopher Mathews.

Honoring undergrads who promote diversity
Diversity

Honoring undergrads
who promote diversity

January 20, 2020

Meet the 2019 recipients of the Marion B. Sewer Scholarship, which is open to all American Society for Biochemistry and Molecular Biology undergraduate members. This year’s deadline is June 1.

Dahms honored; Agre joins board; TWAS fellows
Member News

Dahms honored; Agre joins board; TWAS fellows

January 20, 2020

Awards, promotions and more. Find out what's going on in the lives of ASBMB members.