ASBMB Nobel Prize Winners

1992 - Edmond H. Fischer

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Fischer

Edmond H. Fischer (1920 - present) was the co-recipient of the 1992 Nobel Prize for Physiology or Medicine for his discoveries concerning reversible phosphorylation, the addition of a phosphate group to a protein and one of the biochemical mechanisms that governs the activities of proteins.  Fischer and fellow Nobel Laureate Edwin G. Krebs were the first to purify and characterize one of the enzymes, called phosphorylase, involved in phosphorylation.  They also discovered the enzymes that catalyze the attachment and removal of phosphate groups, known as protein kinases and phosphatase, respectively.