ASBMB Nobel Prize Winners

1977 – Andrew V. Schally



Andrew Victor Schally (1926- present) was awarded one-quarter of the 1977 Nobel Prize in Physiology or Medicine for his work in isolating and synthesizing hormones that are produced by the hypothalamus and control the activities of other hormone-producing glands. Schally synthesized the thyrotropin-releasing hormone (TRH), isolated and synthesized the luteinizing hormone-releasing hormone (LHRH), and studied somatostatin, a peptide hormone that regulates the endocrine system. Also, while collaborating with fellow Nobel Laureate Roger Guillemin, Schally described the brain hormone Gonadotropin-releasing hormone (GnRH), which controls two hormones essential for reproduction: follicle stimulating hormone (FSH) and luteinizing hormone (LH).