Overview

LOCATION: Granlibakken Resort and Conference Center, Tahoe City, CA

DATE: October 21 - October 24, 2010

ORGANIZER:  Katalin Medzihradszky, University of California, San Francisco
                      Gerald Hart, Johns Hopkins University School of Medicine

REGISTRATION:  Available in February 2010    PROGRAM

MEETING SUMMARY

This meeting is supported through generous contributions by:

        

With the completion of the human genome and rapid progress in understanding the proteome, it is now clear that the next phase of molecular bioscience will by necessity largely focus on post-translational modifications (PTMs) and their regulation of protein functions. Currently, there are over four hundred known PTMs, and almost without exception, virtually all polypeptides are post-translationally modified. Given the relatively small numbers of genes and polypeptides in complex organisms, PTMs create the enormous and highly dynamic structural and functional diversity required to regulate essential cellular functions. In recent years, the technologies to quantitatively study PTMs at the molecular and structural level have developed rapidly, particularly in the area of mass spectrometry. This biannual meeting brings together leading experts in the study of a wide variety different PTMs to allow cross fertilization, presentation of the most exciting breakthroughs in the methodology and biological functions of PTMs, and to generate lively discussions of new concepts and approaches.     

Based upon the enormous success of the first meeting held two years ago at Granlibakken, this meeting will not only benefit newcomers to the field of PTMs, but also will provide a forum for sharing current breakthroughs in both methodology and biology to established investigators in the field.