May 1, 2013 — In the May issue of ASBMB Today, we explore what we know — and what we need to know — about sperm and how it relates to male infertility. The fourth and fifth installments of our personal essay series, “Derailed but Undeterred,” are by Christine Guthrie, who candidly tells how she prevailed through a particularly dark period when she was a young investigator, and by Jonathan Gitlin, who recalls the challenges he experienced as a noncitizen forging a career in U.S. science policy. You’ll also find a Retrospective article about the late Wm Wallace “Mo” Cleland and a feature by contributor Diedre Ribbens about the uptake of digital PCR by some researchers seeking to solve certain types of problems. And don’t miss our Journal News highlighting two new minireviews in The Journal of Biological Chemistry, a thematic series on microRNAs in the Journal of Lipid Research and a special issue of Molecular & Celullar Proteomics focused on glycoscience. Read the May issue.