Aug. 1, 2012 — In the August issue of ASBMB Today, science writer Raj Mukhopadhyay explores the promise and challenges of targeted therapies. In this cover story, Journal of Biological Chemistry Associate Editor Richard Hanson of Case Western Reserve University shares his experiences with chronic lymphocytic leukemia and how a new targeted treatment has so far kept him out of “the big lab in the sky.” Meanwhile, four contributors address various issues related to the Ph.D. pipeline. ASBMB Public Affairs Director Benjamin Corb expresses frustration over the recent work-force report by the National Institutes of Health working group. Promega Corp.’s Martin Rosenberg raises concerns about what skills new grads aren’t gaining for today’s job opportunities. Jon Lorsch suggests academic mentors reassess what they consider good outcomes of graduate education. And Carolyn Machamer reports on one way Johns Hopkins University is exposing students to career options outside of the lab. Lastly, don’t miss contributor Cristy Gelling’s insightful and frank feature on the creative ways young researchers are balancing their careers and families. Read the August issue. All issues.