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Molecular Mechanisms of Infection and Immunity

Abstract deadline extended to Monday, November 10 at 5PM, EST

Theme organizers:

Brian Baker Eric Sundberg
Brian Baker
Univ. of Notre Dame 
Eric Sundberg
Univ. of Maryland
School of Medicine 

This theme is made up of four symposia, one scheduled each day of the meeting, Sun – Wed.  Please read below for invited speaker and session schedule information.  In addition to the invited talks listed below, short talks will be selected from the submitted abstracts.  To be considered for a volunteered talk in this theme, submit your abstract to an ASBMB topic category number: 2200-2265, by the November 6th submission deadline.  All volunteered abstracts will be programmed for poster presentation.  Those selected for oral presentation will also present a poster.  Programming notifications will be sent in mid-January.  We look forward to seeing you at the Boston Convention and Exhibition Center, BCEC, March 28 – April 1, 2015.

Glycobiology in Infection and Immunity

Sunday, March 29, 2015, 3:55 PM - 6:10 PM
Room 257A/B

Session Chair: Brian Baker, Univ. of Notre Dame

Invited Speakers:

Peter Kwong, NIH
Antibody recognition of HIV glycans/vaccine design

Eric Sundberg, Univ. of Maryland Sch. of Med.
Microbial manipulation of antibody effector functions

Yvette van Kooyk, Vrije Univ. Med. Ctr., Amsterdam
Glycan targeted vaccines for the induction of immunity

Antigen Presentation and Recognition in Cellular Immunity

Monday, March 30, 2015, 9:45 AM - 12:00 PM
Room 257A/B

Session Chair: Eric Sundberg, Univ. of Maryland Sch. of Med.

Invited Speakers:

Erin Adams, Univ. of Chicago
The molecular signals that regulate gamma delta T cells

Brian Baker, Univ. of Notre Dame
T cell receptor recognition and the composite peptide/MHC surface

David M. Kranz, Univ. of Illinois
Engineering T cell receptors for optimal affinities and desired  

Biochemistry and Systems Biology of Host-Pathogen Interactions

Tuesday, March 31, 2015, 3:55 PM - 6:10 PM
Room 257A/B

Session Chair: David M. Kranz, Univ. of Illinois

Invited Speakers:

Alan Aderem, Univ. of Washington
A Systems Approach to Dissecting Immunity

Nir Hacohen, Harvard Med. Sch., Massachusetts Gen. Hosp.
Genes, networks and variations of the innate immune system

Visualizing Multicomponent Structures in Infection and Immunity

Wednesday, April 1, 2015, 9:00 AM - 11:15 AM
Room 257A/B

Session Chair: Erin Adams, Univ. of Chicago

Invited Speakers:

Edward H. Egelman, Univ. of Virginia
Cryo-EM at near-atomic resolution of bacterial and host filaments

Thomas Marlovits, Inst. Of Molecular Biotechnology, Vienna
EM of pathogen secretion systemsEM of pathogen secretion systems: Unfolded protein transport across membranes in action

Daniela Nicastro, Brandeis Univ.                
Analyzing macromolecular complexes in situ using cellular cryo-electron microscopy