The Human Microbiome

Theme organizers:

Andrew_Goodman Matthew Redinbo
Andrew Goodman
Yale Univ. Sch. of Med 
 Matthew Redinbo
UNC at Chapel Hill


Measuring and Predicting Microbial Community Dynamics

Sunday, March 29, 2015, 9:45 AM - 12:00 PM • Room 254A/B

Follow the conversation: #microbiome

Chaired: L. Hooper

9:45                        Chair’s Introduction.

9:50      91.1          Metagenomic Systems Biology: Metabolic Modeling and Multi-meta-omic Analysis of the Human Microbiome E. Borenstein. Univ. of Washington and Santa Fe Inst.

10:20                      Source Tracking of Fecal Contamination along San Luis Obispo Creek D.R. Shapiro, J.D. Kent, M.F. Zuleta, C.L. Kitts, M.W. Black and J. VanderKelen. California Polytech State Univ., San Luis Obispo. (575.12)

10:35    91.2          Think Globally, Act Locally: Regulated Deployment of Polysaccharide Degradation Abilities by Our Symbiotic Gut Bacteria E. Martens. Univ. of Michigan Med. Sch.

11:05                      Production of Antimicrobial Substances by Nonpathogenic Neisseria Species J. Ogle, A. Finck and E. Aho. Concordia Col., MN. (575.7)

11:20    91.3          The Extraordinary Evolution of the Great Ape Microbiome H. Ochman. Univ. of Texas at Austin.

11:50                      Discussion.

Microbe Host Interaction

Monday, March 30, 2015, 3:55 PM - 6:10 PM • Room 254A/B

Follow the conversation: #microbiome

Chaired: G. Dantas

3:55                        Chair’s Introduction.

4:00      235.1       Microbiome Resilience during Inflammation A. Goodman. Yale Univ.

4:30                        Quantifying Dynamic Host-Microbiota Signatures of Antibiotic-Associated GI Infection: What Can the Host Proteome Tell Us? J.E. Elias, J.S. Lichtman and J.L. Sonnenburg. Stanford Univ. (575.21)

4:45      235.2       Circadian Regulation of Intestinal Host-Microbe Interactions L. Hooper, X. Yu, K. Ruhn, J. Stubblefield, C. Green, M. Kashiwada, P. Rothman and J. Takahashi. Univ. of Texas Southwestern Med. Ctr. and Univ. of Iowa.

5:15                        A Potential Role of H. pylori PPIase in the Transformation of Gastric Epithelial Cell and the Development of Gastric Cancer J. Liu. West Virginia Univ. (575.22)

5:30      235.3       Sphingolipids of Commensals Modulate Host Immunity through Regulation of iNKT Cells D. Kasper. Harvard Med. Sch.

6:00                        Discussion.

Chemistry of Commensal Biology

Tuesday, March 31, 2015, 9:45 AM - 12:00 PM • Room 254A/B

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Chaired: S. Mani  

9:45                        Chair’s Introduction.

9:50      358.1       Expanding the Language of Bacterial Quorum Sensing Using Synthetic Ligands H. Blackwell. Univ. of Wisconsin-Madison.

10:20                      Functional Association Profiling of Metabolic Landscape and Microbiome in Chronic Pressure Ulcer Wounds M.C.B. Ammons and V. Copie. Montana State Univ. (575.19)

10:35    358.2       How Gut Bacteroides Eat Your Veggies N. Koropatkin. Univ. of Michigan Med. Sch.

11:05    358.3       Chemical Tools for Studying the Activation of the Intracellular Innate Immune Protein Nod2 C.L. Grimes and J. Melnyk. University of Delaware.

11:20    358.4       A Milk-Oriented Microbiota (MOM) in Infants: Lessons from your Other MOM D. Mills. Univ. of California, Davis.

11:50                      Discussion.

Gut Microbes, Drugs and Toxins

Wednesday, April 1, 2015, 1:15 PM - 3:30 PM • Room 254A/B

Follow the conversation: #microbiome

Chaired: A. Goodman

1:15                        Chair’s Introduction.

1:20      494.1       Networks of Exchanging Antibiotic Resistomes in Human and Environmental Microbiota G. Dantas. Washington Univ. Sch. of Med.

1:50                        Toxin-Antitoxin Systems and Their Role(s) in Persistence R. Page and W. Peti. Brown Univ. (575.23)

2:05                         Gut Reactions: Using Chemistry to Understand the Microbiota.  E. Balskus.  Harvard Univ.  

2:35                        Neonatal Antibiotic Exposure Alters Compositional Gut Microbiota Development during the First 6 Months of Life H. Kumar, S. Rautava, M.C. Collado, N. Borzykh, E. Löyttyniemi, E. Isolauri and S. Salminen. Fac. of Med., Univ. of Turku, Finland and IATA-CSIC, Spain. (575.3)

2:50      494.3       Engineering the microbiome to cure recurrent Clostridium difficile infection.  E. Alm. Broad Inst., MIT

3:20                        Discussion.