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New Directions in Enzymology

Theme organizers:
Kate S. Carroll, The Scripps Res. Inst. and Liz Hedstrom, Brandeis Univ.

This theme is made up of four symposia, one scheduled each day of the meeting, Sun – Wed.  Please read below for invited speaker and session schedule information.  In addition to the invited talks listed below, short talks will be selected from the submitted abstracts.  To be considered for a volunteered talk in this theme, submit your abstract to an ASBMB topic category number: 2270-2287, by the November 8th submission deadline.  All volunteered abstracts will be programmed for poster presentation.  Those selected for oral presentation will also present a poster.  Programming notifications will be sent in mid-January.  We look forward to seeing you at the Boston Convention and Exhibition Center, BCEC, March 28 – April 1, 2015.

New Reactions of Old Cofactors

Sunday, March 29, 2015, Session time tba

Session Chair: Kate S. Carroll, The Scripps Res. Inst.

Invited Speakers:

Lizbeth Hedstrom, Brandeis Univ.
Cofactor dynamics in GMP reductase

Tadgh P. Begley, Texas A&M Univ.
The mechanistic enzymology of thiamin biosynthesis

Bradley Moore, UCSD
Natural product biosynthesis - A treasure trove of multitalented flavoenzymes

Discovering New Enzymes

Monday, March 30, 2015, Session time tba

Session Chair: Hening Lin, Cornell Univ.

Invited Speakers: Frank M. Raushel, Texas A&M Univ.
New Enzyme Discovery in the Amidohydrolase Superfamily

Karen N. Allen, Boston Univ.
Evolution of Function in a Superfamily of Phosphatases

Margaret A. Phillips, UT Southwestern Med. Ctr.
Pseudoenzymes as activators of enzyme function: the prozyme paradigm in trypanosomatid polyamine metabolism

Enzyme Modules and Complexes

Tuesday, March 31, 2015, Session time tba

Session Chair: Karen Allen, Boston Univ.

Invited Speakers:

Francisco J. Asturias, The Scripps Res. Inst.
Quaternary structure and activity modulation in human ribonucleotide reductase

Vicki Hopper Wysocki, The Ohio State Univ.
Characterization of Protein Complexes by Surface-Induced Dissociation Ion Mobility Mass Spectrometry

Eileen K. Jaffe, Fox Chase Cancer Ctr., Temple UHS
The morpheein model of protein allostery - an anomaly or an overlooked generalization

Strategies for Substrate Recognition

Wednesday, April 1, 2015, Session time tba

Session Chair: Liz Hedstrom, Brandeis Univ.

Invited Speakers: Kate S. Carroll, The Scripps Res. Inst.
Diverse Target Recognition and Disulfide Reduction by Thioredoxin

Hening Lin, Cornell Univ.
Sirtuins and novel protein posttranslational modifications

Wilfred van der Donk, Univ. of Illinois
Substrate recognition in Lanthipeptide Synthesis

 

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