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RNA Expression and Posttranscriptional Regulatory Events

Theme organizers:
Grace Gill, Tufts Univ. Sch. of Med. and Yan Jessie Zhang, Univ. of Texas, Austin

This theme is made up of four symposia, one scheduled each day of the meeting, Sun – Wed.  Please read below for invited speaker and session schedule information.  In addition to the invited talks listed below, short talks will be selected from the submitted abstracts.  To be considered for a volunteered talk in this theme, submit your abstract to an ASBMB topic category number: 2040-2063, by the November 8th submission deadline.  All volunteered abstracts will be programmed for poster presentation.  Those selected for oral presentation will also present a poster.  Programming notifications will be sent in mid-January.  We look forward to seeing you at the Boston Convention and Exhibition Center, BCEC, March 28 – April 1, 2015.

Structure and Function of the Transcription Machinery

Sunday, March 29, 2015, Session time tba

Session Chair: Grace Gill, Tufts Univ. Sch. of Med.           

Invited Speakers:

Jeff L. Corden, John Hopkins Univ.
Genome-wide mapping of RNA polymerase II termination sites

Dong Wang, UCSD
Functional interplay between epigenetic DNA modifications and RNA polymerase II transcriptional machinery

Yan Jessie Zhang, Univ. of Texas, Austin
Cross-talk of CTD phosphorylation and isomerization

Making Mature RNA

Monday, March 30, 2015, Session time tba

Session Chair: John T. Lis, Cornell Univ.

Invited Speakers:

David Bentley, Univ. of Colorado
Coupling of transcription with mRNA processing in time and space

Akiko Hata, Cardiovascular Res. Inst. UCSF
Role of microRNA processing enzyme in vascular development 

Ian Mac Rae, The Scripps Res. Inst.
Structural basis for gene silencing by argonaute proteins

Cross-talk between RNA, Transcription and Chromatin

Tuesday, March 31, 2015, Session time tba

Session Chair: David Bentley, Univ. of Colorado, Denver

Invited Speakers:

Jeannie T. Lee, HHMI, Mass. Gen. Hosp., Harvard Med. Sch.
X-inactivation as a model for epigenetic regulation by long noncoding RNA

Danesh Moazed, Harvard Med. Sch.
Regulation of chromatin by noncoding RNA and RNAi

Ramin Shiekhattar, Univ. of Miami
Biogenesis and mechanism of action of enhancer RNAs

RNA Expression and Cell Fate

Wednesday, April 1, 2015, Session time tba

Session Chair: Yan Jessie Zhang, Univ. of Texas, Austin

Invited Speakers:

Xiang-Dong Fu, UCSD
Efficient conversion of human fibroblasts to functional neurons by sequential inactivation of PTB/nPTB-regulated RNA programs

Grace Gill, Tufts Univ. Sch. of Med.
Transcriptional repression and cell identity

John T. Lis, Cornell Univ.
Probing mechanisms of transcription regulation in vivo


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