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DNA Replication and Repair

Theme organizers:

 
Michael G. Fried, Univ. of Kentucky   Myron F. Goodman, USC

 

This theme is made up of four symposia, one scheduled each day of the meeting, Sun – Wed.  Please read below for invited speaker and session schedule information.  In addition to the invited talks listed below, short talks will be selected from the submitted abstracts.  To be considered for a volunteered talk in this theme, submit your abstract to an ASBMB topic category number: 2000-2022, by the November 6th submission deadline.  All volunteered abstracts will be programmed for poster presentation.  Those selected for oral presentation will also present a poster.  Programming notifications will be sent in mid-January.  We look forward to seeing you at the Boston Convention and Exhibition Center, BCEC, March 28 – April 1, 2015.

Engaging Stalled Replication Forks           

Sunday, March 29, 2015, 3:55 PM - 6:10 PM
Room 258B

Session Chair: Michael G. Fried, Univ. of Kentucky

Invited Speakers:

Peter M. J. Burgers, Washington Univ. Sch. Of Med., St. Louis
Biochemical regulation of lesion bypass

Myron F. Goodman, USC
Biochemical determinants of translesion DNA synthesis

Wei Yang, NIDDK, NIH
Translesion DNA synthesis

Super-resolution Replication Studies

Monday, March 30, 2015, 9:45 AM - 12:00 PM
Room 258B

Session Chair: Myron F. Goodman, USC

Invited Speakers:

Lorena Beese, Duke Univ. Med. Ctr.
Structural aspects of replication fidelity and mismatch repair

David Sheratt, Univ. of Oxford
Live cell imaging studies of proteins involved in 3R

Antoine M. van Oijen, Univ. of Groningen
Live Cell Imaging Studies of Damaged-induced DNA Polymerases

DNA Topology and Repair

Tuesday, March 31, 2015, 3:55 PM - 6:10 PM
Room 258B

Session Chair: Laura Lindsey-Boltz, UNC at Chapel Hill

Invited Speakers:

Steven Kowalczykowski, UC, Davis
Visualizing replication and recombination on single molecules of DNA

Yves Pommier, NCI, NIH
Topoisomerase-induced DNA cleavage at ribonucleotide misincorporation sites

Deborah S. Wuttke, Univ. of Colorado, Boulder
Tying up the Ends: Recognition of ssDNA at Telomeres

Cooperativity and Crosstalk

Wednesday, April 1, 2015, 9:00 AM - 11:15 AM
Room 258B

Session Chair: Deborah S. Wuttke, Univ. of Colorado, Boulder

Invited Speakers:

Michael G. Fried, Univ. of Kentucky
Crosstalk in DNA-alkyltransferase and MutS functions

Laura Lindsey-Boltz, UNC at Chapel Hill
Coupling of human DNA excision repair and the ATR-mediated DNA damage checkpoint

Evgeny Nudler, HHMI/NYU Langone Med. Ctr.
A new look at transcription-coupled DNA repair